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36 results

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Page 1
Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827.
Fraguas Bringas C, Ahangar MS, Cuenco J, Liu H, Addinsall AB, Lindahl M, Ovens AJ, Febbraio MA, Foretz M, Göransson O, Scott JW, Zeqiraj E, Sakamoto K. Fraguas Bringas C, et al. Among authors: zeqiraj e. Sci Adv. 2025 Aug 22;11(34):eadx2434. doi: 10.1126/sciadv.adx2434. Epub 2025 Aug 22. Sci Adv. 2025. PMID: 40845097 Free PMC article.
A programmed decline in ribosome levels governs human early neurodevelopment.
Ni C, Wei Y, Vona B, Park D, Wei Y, Schmitz DA, Ding Y, Sakurai M, Ballard E, Li L, Liu Y, Kumar A, Xing C, Qin S, Kim S, Foglizzo M, Zhao J, Kim HG, Ekmekci C, Karimiani EG, Imannezhad S, Eghbal F, Badv RS, Schwaibold EMC, Dehghani M, Mehrjardi MYV, Metanat Z, Eslamiyeh H, Khouj E, Alhajj SMN, Chedrawi A, Ramzan K, Hashmi JA, Alluqmani MM, Basit S, Veltra D, Marinakis NM, Niotakis G, Vorgia P, Sofocleous C, Lee H, Jeong WC, Umair M, Bilal M, Alves CAPF, Sieber M, Kruer M, Houlden H, Alkuraya FS, Zeqiraj E, Greenberg RA, Cenik C, Yu L, Maroofian R, Wu J, Buszczak M. Ni C, et al. Among authors: zeqiraj e. Nat Cell Biol. 2025 Aug;27(8):1240-1255. doi: 10.1038/s41556-025-01708-8. Epub 2025 Aug 4. Nat Cell Biol. 2025. PMID: 40760247 Free PMC article.
Molecular glues that inhibit deubiquitylase activity and inflammatory signaling.
Chandler F, Reddy PAN, Bhutda S, Ross RL, Datta A, Walden M, Walker K, Di Donato S, Cassel JA, Prakesch MA, Aman A, Datti A, Campbell LJ, Foglizzo M, Bell L, Stein DN, Ault JR, Al-Awar RS, Calabrese AN, Sicheri F, Del Galdo F, Salvino JM, Greenberg RA, Zeqiraj E. Chandler F, et al. Among authors: zeqiraj e. Nat Struct Mol Biol. 2025 Sep;32(9):1812-1824. doi: 10.1038/s41594-025-01517-5. Epub 2025 Mar 17. Nat Struct Mol Biol. 2025. PMID: 40097626 Free PMC article.
Structure and function of MDM2 and MDM4 in health and disease.
Zhu IY, Lloyd A, Critchley WR, Saikia Q, Jade D, Divan A, Zeqiraj E, Harrison MA, Brown CJ, Ponnambalam S. Zhu IY, et al. Among authors: zeqiraj e. Biochem J. 2025 Feb 17;482(4):BCJ20240757. doi: 10.1042/BCJ20240757. Biochem J. 2025. PMID: 39960347 Free PMC article. Review.
Molecular glues that inhibit deubiquitylase activity and inflammatory signalling.
Chandler F, Reddy PAN, Bhutda S, Ross RL, Datta A, Walden M, Walker K, Di Donato S, Cassel JA, Prakesch MA, Aman A, Datti A, Campbell LJ, Foglizzo M, Bell L, Stein DN, Ault JR, Al-Awar RS, Calabrese AN, Sicheri F, Del Galdo F, Salvino JM, Greenberg RA, Zeqiraj E. Chandler F, et al. Among authors: zeqiraj e. bioRxiv [Preprint]. 2024 Nov 15:2024.09.07.611787. doi: 10.1101/2024.09.07.611787. bioRxiv. 2024. Update in: Nat Struct Mol Biol. 2025 Sep;32(9):1812-1824. doi: 10.1038/s41594-025-01517-5. PMID: 39282282 Free PMC article. Updated. Preprint.
36 results