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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 30
1947 24
1948 37
1949 19
1950 39
1951 45
1952 50
1953 52
1954 56
1955 52
1956 56
1957 62
1958 54
1959 72
1960 67
1961 79
1962 89
1963 128
1964 180
1965 94
1966 99
1967 260
1968 479
1969 694
1970 864
1971 1091
1972 1230
1973 1174
1974 1214
1975 1027
1976 763
1977 805
1978 772
1979 759
1980 693
1981 779
1982 789
1983 829
1984 1036
1985 1284
1986 1433
1987 1304
1988 1442
1989 1607
1990 1662
1991 1870
1992 2042
1993 2328
1994 2465
1995 2821
1996 2731
1997 2927
1998 3120
1999 3090
2000 3104
2001 3077
2002 3121
2003 3315
2004 3353
2005 3461
2006 3622
2007 3739
2008 3955
2009 4000
2010 4232
2011 4313
2012 4395
2013 4439
2014 4321
2015 4299
2016 4418
2017 4309
2018 4193
2019 4390
2020 4272
2021 3860
2022 2779
2023 2385
2024 2891
2025 3275
2026 1488

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137,078 results

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Page 1
Stages of embryonic development of the zebrafish.
Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Kimmel CB, et al. Dev Dyn. 1995 Jul;203(3):253-310. doi: 10.1002/aja.1002030302. Dev Dyn. 1995. PMID: 8589427 Free article.
These divisions highlight the changing spectrum of major developmental processes that occur during the first 3 days after fertilization, and we review some of what is known about morphogenesis and other significant events that occur during each of the periods. Stages subdi …
These divisions highlight the changing spectrum of major developmental processes that occur during the first 3 days after fertilization, and …
Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.
Wang S, Matsumoto K, Lish SR, Cartagena-Rivera AX, Yamada KM. Wang S, et al. Cell. 2021 Jul 8;184(14):3702-3716.e30. doi: 10.1016/j.cell.2021.05.015. Epub 2021 Jun 15. Cell. 2021. PMID: 34133940 Free PMC article.
Many embryonic organs undergo epithelial morphogenesis to form tree-like hierarchical structures. However, it remains unclear what drives the budding and branching of stratified epithelia, such as in the embryonic salivary gland and pancreas. Here, we …
Many embryonic organs undergo epithelial morphogenesis to form tree-like hierarchical structures. However, it remains u …
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
Spence JR, Mayhew CN, Rankin SA, Kuhar MF, Vallance JE, Tolle K, Hoskins EE, Kalinichenko VV, Wells SI, Zorn AM, Shroyer NF, Wells JM. Spence JR, et al. Nature. 2011 Feb 3;470(7332):105-9. doi: 10.1038/nature09691. Epub 2010 Dec 12. Nature. 2011. PMID: 21151107 Free PMC article.
Studies in embryonic development have guided successful efforts to direct the differentiation of human embryonic and induced pluripotent stem cells (PSCs) into specific organ cell types in vitro. ...Here we establish a robust and efficient process to direct the diff …
Studies in embryonic development have guided successful efforts to direct the differentiation of human embryonic and induced p …
Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids.
Liu L, Oura S, Markham Z, Hamilton JN, Skory RM, Li L, Sakurai M, Wang L, Pinzon-Arteaga CA, Plachta N, Hon GC, Wu J. Liu L, et al. Cell. 2023 Aug 31;186(18):3776-3792.e16. doi: 10.1016/j.cell.2023.07.018. Epub 2023 Jul 20. Cell. 2023. PMID: 37478861 Free article.
In vitro stem cell models that replicate human gastrulation have been generated, but they lack the essential extraembryonic cells needed for embryonic development, morphogenesis, and patterning. Here, we describe a robust and efficient method that prompts human exte …
In vitro stem cell models that replicate human gastrulation have been generated, but they lack the essential extraembryonic cells needed for …
Signaling mechanisms that direct cell fate specification and morphogenesis in human embryonic stem cells-based models of human gastrulation.
Stringa B, Solnica-Krezel L. Stringa B, et al. Emerg Top Life Sci. 2023 Dec 18;7(4):383-396. doi: 10.1042/ETLS20230084. Emerg Top Life Sci. 2023. PMID: 38087898 Review.
This is changing with the unprecedented progress in modeling aspects of human development, using human pluripotent stem cells (hPSCs), including embryonic stem cells (hESC)-based embryo-like models (SCEMs). In one approach, hESCs of various pluripotency are aggregated to s …
This is changing with the unprecedented progress in modeling aspects of human development, using human pluripotent stem cells (hPSCs), inclu …
Whole Mount Immunohistochemistry in Zebrafish Embryos and Larvae.
Hammond-Weinberger DR, ZeRuth GT. Hammond-Weinberger DR, et al. J Vis Exp. 2020 Jan 29;(155). doi: 10.3791/60575. J Vis Exp. 2020. PMID: 32065134
This protocol is broadly applicable to the study of many developmental stages and embryonic structures....
This protocol is broadly applicable to the study of many developmental stages and embryonic structures....
How the cytoskeleton helps build the embryonic body plan: models of morphogenesis from Drosophila.
Harris TJ, Sawyer JK, Peifer M. Harris TJ, et al. Curr Top Dev Biol. 2009;89:55-85. doi: 10.1016/S0070-2153(09)89003-0. Curr Top Dev Biol. 2009. PMID: 19737642 Review.
One key challenge for cell and developmental biologists is to determine how the cytoskeletal toolkit is used to build embryonic tissues and organs. Here, we review recent progress in meeting this challenge, focusing on epithelial morphogenesis in the Drosophila embr …
One key challenge for cell and developmental biologists is to determine how the cytoskeletal toolkit is used to build embryonic tissu …
Exploring the principles of embryonic mammary gland branching morphogenesis.
Satta JP, Lindström R, Myllymäki SM, Lan Q, Trela E, Prunskaite-Hyyryläinen R, Kaczyńska B, Voutilainen M, Kuure S, Vainio SJ, Mikkola ML. Satta JP, et al. Development. 2024 Aug 1;151(15):dev202179. doi: 10.1242/dev.202179. Epub 2024 Aug 2. Development. 2024. PMID: 39092607
Branching morphogenesis is a characteristic feature of many essential organs, such as the lung and kidney, and most glands, and is the net result of two tissue behaviors: branch point initiation and elongation. Each branched organ has a distinct architecture customized to …
Branching morphogenesis is a characteristic feature of many essential organs, such as the lung and kidney, and most glands, and is th …
Embryonic stem cell model systems for vascular morphogenesis and cardiac disorders.
Doetschman T, Shull M, Kier A, Coffin JD. Doetschman T, et al. Hypertension. 1993 Oct;22(4):618-29. doi: 10.1161/01.hyp.22.4.618. Hypertension. 1993. PMID: 8406668 Review.
Production of this model is based on the ability of blastocyst-derived embryonic stem cells, which can be genetically altered in vitro by a technique called gene targeting, to reconstitute an entire animal when reintroduced into a blastocyst and allowed to colonize the ger …
Production of this model is based on the ability of blastocyst-derived embryonic stem cells, which can be genetically altered in vitr …
Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage.
Chandramohan D, Yan R, Kruse K, Brinkmann H, Jeong HW, Hou Y, Adachi K, Schöler HR, Bedzhov I. Chandramohan D, et al. Dev Cell. 2026 Mar 11;61(3):621-637.e5. doi: 10.1016/j.devcel.2025.11.003. Epub 2025 Dec 2. Dev Cell. 2026. PMID: 41338198 Free article.
A key driver of embryonic morphogenesis is the establishment of epithelial polarity, which organizes and structures the early cell layers. ...Thus, Oct4 and Sox2 simultaneously govern developmental capacity and regulate the developmental timing of tissue m …
A key driver of embryonic morphogenesis is the establishment of epithelial polarity, which organizes and structures the …
137,078 results
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