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Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y. Zou G, et al. Theranostics. 2020 May 22;10(15):6839-6853. doi: 10.7150/thno.43622. eCollection 2020. Theranostics. 2020. PMID: 32550907 Free PMC article.
Results: We identified emodin that could greatly increase SerRS expression in TNBC cells, consequently reducing VEGFA transcription. ...We also identified nuclear receptor corepressor 2 (NCOR2) to be the direct target of emodin. Once bound by emodin, NCOR2 go …
Results: We identified emodin that could greatly increase SerRS expression in TNBC cells, consequently reducing VEGFA transcription. …
Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation.
Liu Q, Hodge J, Wang J, Wang Y, Wang L, Singh U, Li Y, Yao Y, Wang D, Ai W, Nagarkatti P, Chen H, Xu P, Murphy EA, Fan D. Liu Q, et al. Theranostics. 2020 Jul 9;10(18):8365-8381. doi: 10.7150/thno.45395. eCollection 2020. Theranostics. 2020. PMID: 32724475 Free PMC article.
The effects of emodin on TGF-beta1 signaling pathways in breast cancer cells were examined by western blots and immunofluorescent imaging. ...Conclusion: Natural compound emodin suppresses EMT and CSC formation of breast cancer cells by blocking TGF-be …
The effects of emodin on TGF-beta1 signaling pathways in breast cancer cells were examined by western blots and immunofluoresc …
Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.
Shrimali D, Shanmugam MK, Kumar AP, Zhang J, Tan BK, Ahn KS, Sethi G. Shrimali D, et al. Cancer Lett. 2013 Dec 1;341(2):139-49. doi: 10.1016/j.canlet.2013.08.023. Epub 2013 Aug 17. Cancer Lett. 2013. PMID: 23962559 Review.
As an anti-cancer agent, emodin has been shown to suppress the growth of various tumor cell lines including hepatocellular carcinoma, pancreatic, breast, colorectal, leukemia, and lung cancers. ...This review summarizes reported anti-inflammatory and anti- …
As an anti-cancer agent, emodin has been shown to suppress the growth of various tumor cell lines including hepatocellular car …
ACSL4 promotes colorectal cancer and is a potential therapeutic target of emodin.
Dai G, Wang D, Ma S, Hong S, Ding K, Tan X, Ju W. Dai G, et al. Phytomedicine. 2022 Jul 20;102:154149. doi: 10.1016/j.phymed.2022.154149. Epub 2022 May 6. Phytomedicine. 2022. PMID: 35567995
Several studies have demonstrated that emodin, the main ingredient of Rheum palmatum, fights cancer but its potential anti-tumor effect on CRC is still unknown. ...A docking simulation assay and an MST assay were performed to explore the potential mode of emodin …
Several studies have demonstrated that emodin, the main ingredient of Rheum palmatum, fights cancer but its potential anti-tum …
Emodin Induced Necroptosis and Inhibited Glycolysis in the Renal Cancer Cells by Enhancing ROS.
Wang KJ, Meng XY, Chen JF, Wang KY, Zhou C, Yu R, Ma Q. Wang KJ, et al. Oxid Med Cell Longev. 2021 Jan 19;2021:8840590. doi: 10.1155/2021/8840590. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 33532038 Free PMC article.
Flow cytometry assay with Annexin V-FITC and PI demonstrated that emodin induces necroptosis, but not apoptosis, in renal cancer cells. ...Our findings revealed the potential mechanisms by which emodin suppresses renal cancer cell growth and will help …
Flow cytometry assay with Annexin V-FITC and PI demonstrated that emodin induces necroptosis, but not apoptosis, in renal cancer …
The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin.
Cui Y, Chen LJ, Huang T, Ying JQ, Li J. Cui Y, et al. Chin J Nat Med. 2020 Jun;18(6):425-435. doi: 10.1016/S1875-5364(20)30050-9. Chin J Nat Med. 2020. PMID: 32503734 Review.
Based on the fundamental properties, such as anticancer, anti-inflammatory, antioxidant, antibacterial, antivirs, anti-diabetes, immunosuppressive and osteogenesis promotion, emodin is expected to become an effective preventive and therapeutic drug of cancer, myocar …
Based on the fundamental properties, such as anticancer, anti-inflammatory, antioxidant, antibacterial, antivirs, anti-diabetes, immunosuppr …
Emodin - A natural anthraquinone derivative with diverse pharmacological activities.
Semwal RB, Semwal DK, Combrinck S, Viljoen A. Semwal RB, et al. Phytochemistry. 2021 Oct;190:112854. doi: 10.1016/j.phytochem.2021.112854. Epub 2021 Jul 24. Phytochemistry. 2021. PMID: 34311280 Review.
Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone derivative that is present in numerous globally renowned herbal medicines. ...Although reviews on the anticancer activity of emodin have been published, none coherently unite all the pharmac …
Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone derivative that is present in numerous globally renowned …
Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer.
Gao J, Yang S, Xie G, Pan J, Zhu F. Gao J, et al. Drug Des Devel Ther. 2022 Jun 20;16:1947-1961. doi: 10.2147/DDDT.S360790. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35757520 Free PMC article.
PURPOSE: This study was designed to evaluate the pharmacological mechanisms of Aloin against gastric cancer (GC) via network pharmacology analysis combined with experimental verification. ...GO enrichment analysis involved 93 biological processes, 19 cellular components, a …
PURPOSE: This study was designed to evaluate the pharmacological mechanisms of Aloin against gastric cancer (GC) via network pharmaco …
Emodin induces apoptosis and suppresses non-small-cell lung cancer growth via downregulation of sPLA2-IIa.
Zhang FY, Li RZ, Xu C, Fan XX, Li JX, Meng WY, Wang XR, Liang TL, Guan XX, Pan HD, Liu L, Yao XJ, Wu QB, Leung EL. Zhang FY, et al. Phytomedicine. 2022 Jan;95:153786. doi: 10.1016/j.phymed.2021.153786. Epub 2021 Oct 1. Phytomedicine. 2022. PMID: 34785104
BACKGROUND: Lung cancer has become the principal cause of cancer-related deaths. Emodin is a Chinese herb-derived compound extracted from the roots of Rheum officinale that exhibits numerous pharmacological characteristics. Secretory phospholipase A2-IIa (sPL …
BACKGROUND: Lung cancer has become the principal cause of cancer-related deaths. Emodin is a Chinese herb-derived compo …
Advances in Understanding the Role of Aloe Emodin and Targeted Drug Delivery Systems in Cancer.
Şeker Karatoprak G, Küpeli Akkol E, Yücel Ç, Bahadır Acıkara Ö, Sobarzo-Sánchez E. Şeker Karatoprak G, et al. Oxid Med Cell Longev. 2022 Jan 18;2022:7928200. doi: 10.1155/2022/7928200. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35087619 Free PMC article. Review.
The anticancer property of aloe emodin, a broad-spectrum inhibitory agent of cancer cells, has been detailed in many biological pathways. ...In accordance with the strategy of developing potential drug candidates from natural products, aloe emodin's lo …
The anticancer property of aloe emodin, a broad-spectrum inhibitory agent of cancer cells, has been detailed in many biologica …
795 results

Searches related to "emodin cancer"