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8,326 results

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Page 1
History of cannabis and the endocannabinoid system.
Crocq MA. Crocq MA. Dialogues Clin Neurosci. 2020 Sep;22(3):223-228. doi: 10.31887/DCNS.2020.22.3/mcrocq. Dialogues Clin Neurosci. 2020. PMID: 33162765 Free PMC article. Review.
This article retraces the story of cannabis from the earliest contacts of humans with the plant to its subsequent global expansion, its medicinal uses, and the discovery of the endocannabinoid system in the 20(th) century. Cannabis was attested to around 12 000 year …
This article retraces the story of cannabis from the earliest contacts of humans with the plant to its subsequent global expansion, its medi …
The Endocannabinoid System: A Potential Target for the Treatment of Various Diseases.
Lowe H, Toyang N, Steele B, Bryant J, Ngwa W. Lowe H, et al. Int J Mol Sci. 2021 Aug 31;22(17):9472. doi: 10.3390/ijms22179472. Int J Mol Sci. 2021. PMID: 34502379 Free PMC article. Review.
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a balance in internal environment (temperature, mood, and immune system) and energy input and output in living, biological systems. ...The distribution of the compon …
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a balance in internal environment (temp …
The Endocannabinoid System and Physical Exercise.
Matei D, Trofin D, Iordan DA, Onu I, Condurache I, Ionite C, Buculei I. Matei D, et al. Int J Mol Sci. 2023 Jan 19;24(3):1989. doi: 10.3390/ijms24031989. Int J Mol Sci. 2023. PMID: 36768332 Free PMC article. Review.
The endocannabinoid system (ECS) is involved in various processes, including brain plasticity, learning and memory, neuronal development, nociception, inflammation, appetite regulation, digestion, metabolism, energy balance, motility, and regulation of stress and em …
The endocannabinoid system (ECS) is involved in various processes, including brain plasticity, learning and memory, neuronal d …
Cannabinoids and the expanded endocannabinoid system in neurological disorders.
Cristino L, Bisogno T, Di Marzo V. Cristino L, et al. Nat Rev Neurol. 2020 Jan;16(1):9-29. doi: 10.1038/s41582-019-0284-z. Epub 2019 Dec 12. Nat Rev Neurol. 2020. PMID: 31831863 Review.
The discovery of CB2 and of endogenous cannabinoid receptor ligands (endocannabinoids) raised new possibilities for safe targeting of this endocannabinoid system. However, clinical success has been limited, complicated by the discovery of an expanded endoc …
The discovery of CB2 and of endogenous cannabinoid receptor ligands (endocannabinoids) raised new possibilities for safe targeting of …
Endocannabinoid System Components: Overview and Tissue Distribution.
Joshi N, Onaivi ES. Joshi N, et al. Adv Exp Med Biol. 2019;1162:1-12. doi: 10.1007/978-3-030-21737-2_1. Adv Exp Med Biol. 2019. PMID: 31332731 Review.
Evidence based research and remarkable biotechnological advances demonstrate that phytocannabinoids and endocannabinoid (eCBs) acting on cannabinoid receptors (CBRs) regulate various aspects of human physiological, behavioral, immunological and metabolic functions. The dis …
Evidence based research and remarkable biotechnological advances demonstrate that phytocannabinoids and endocannabinoid (eCBs) acting …
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System.
Zou S, Kumar U. Zou S, et al. Int J Mol Sci. 2018 Mar 13;19(3):833. doi: 10.3390/ijms19030833. Int J Mol Sci. 2018. PMID: 29533978 Free PMC article. Review.
The CB1R is the prominent subtype in the central nervous system (CNS) and has drawn great attention as a potential therapeutic avenue in several pathological conditions, including neuropsychological disorders and neurodegenerative diseases. ...In this review, we briefly su …
The CB1R is the prominent subtype in the central nervous system (CNS) and has drawn great attention as a potential therapeutic avenue …
The Endocannabinoid System and its Modulation by Phytocannabinoids.
Di Marzo V, Piscitelli F. Di Marzo V, et al. Neurotherapeutics. 2015 Oct;12(4):692-8. doi: 10.1007/s13311-015-0374-6. Neurotherapeutics. 2015. PMID: 26271952 Free PMC article. Review.
The endocannabinoid system is currently defined as the ensemble of the two 7-transmembrane-domain and G protein-coupled receptors for delta(9)-tetrahydrocannabinol (but not for most other plant cannabinoids or phytocannabinoids)-cannabinoid receptor type-1 (CB1R) an …
The endocannabinoid system is currently defined as the ensemble of the two 7-transmembrane-domain and G protein-coupled recept …
Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions.
Spanagel R. Spanagel R. Dialogues Clin Neurosci. 2020 Sep;22(3):241-250. doi: 10.31887/DCNS.2020.22.3/rspanagel. Dialogues Clin Neurosci. 2020. PMID: 33162767 Free PMC article. Review.
The last decades have seen a major gain in understanding the action of cannabinoids and the endocannabinoid system in reward processing and the development of addictive behavior. Cannabis-derived psychoactive compounds such as delta(9)-tetrahydrocannabinol and synth …
The last decades have seen a major gain in understanding the action of cannabinoids and the endocannabinoid system in reward p …
Cannabis, the Endocannabinoid System and Immunity-the Journey from the Bedside to the Bench and Back.
Almogi-Hazan O, Or R. Almogi-Hazan O, et al. Int J Mol Sci. 2020 Jun 23;21(12):4448. doi: 10.3390/ijms21124448. Int J Mol Sci. 2020. PMID: 32585801 Free PMC article. Review.
The phyto-cannabinoid activity is mediated by the endocannabinoid system. Cannabinoids affect the nervous system and play significant roles in the regulation of the immune system. ...In this contemporary review, we discuss the roles of the endocanna …
The phyto-cannabinoid activity is mediated by the endocannabinoid system. Cannabinoids affect the nervous system and pl …
Molecular Mechanism and Cannabinoid Pharmacology.
Schurman LD, Lu D, Kendall DA, Howlett AC, Lichtman AH. Schurman LD, et al. Handb Exp Pharmacol. 2020;258:323-353. doi: 10.1007/164_2019_298. Handb Exp Pharmacol. 2020. PMID: 32236882 Free PMC article.
These pharmacological tools were instrumental in the ultimate discovery of the endogenous cannabinoid system, which consists of CB(1) and CB(2) cannabinoid receptors and endogenously produced ligands (endocannabinoids), which bind and activate both cannabinoid recep …
These pharmacological tools were instrumental in the ultimate discovery of the endogenous cannabinoid system, which consists of CB(1) …
8,326 results