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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1933 1
1950 1
1955 2
1957 1
1958 1
1959 1
1960 2
1961 1
1962 1
1963 4
1964 8
1966 6
1967 5
1968 2
1969 6
1971 1
1972 2
1973 5
1974 4
1975 5
1976 4
1977 6
1978 4
1979 1
1980 2
1981 3
1982 1
1984 3
1985 4
1986 1
1987 1
1988 2
1989 2
1990 3
1991 4
1992 4
1993 4
1994 3
1995 5
1996 3
1997 5
1998 9
1999 7
2000 4
2001 3
2002 5
2003 4
2004 7
2005 17
2006 4
2007 3
2008 5
2009 6
2010 5
2011 5
2012 9
2013 4
2014 6
2015 8
2016 3
2017 8
2018 6
2019 9
2020 10
2021 10
2022 8
2023 9
2024 2

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284 results

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Page 1
Ephedrine causes liver toxicity in SD rats via oxidative stress and inflammatory responses.
Wen S, Liao T. Wen S, et al. Hum Exp Toxicol. 2021 Jan;40(1):16-24. doi: 10.1177/0960327120943938. Epub 2020 Jul 30. Hum Exp Toxicol. 2021. PMID: 32729338
The mechanism of ephedrine-induced toxicity still remains unclear. This study was performed to investigate the effects of ephedrine treatment on the liver and explore the underlying mechanisms. ...Our study demonstrated that short-term treatment of ephedri …
The mechanism of ephedrine-induced toxicity still remains unclear. This study was performed to investigate the effects of e …
Plant Alkaloids Toxicity.
Vezikov LV, Simpson M. Vezikov LV, et al. 2023 Apr 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Apr 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 36508538 Free Books & Documents.
In certain cases, one alkaloid may serve as the antidote for the toxicity of another. Since the discovery of morphine by modern chemistry, through repurposing and metabolic engineering, plant alkaloids have been exploited for their immense medicinal properties in a wealth …
In certain cases, one alkaloid may serve as the antidote for the toxicity of another. Since the discovery of morphine by modern chemi …
Effects of Chronic Ephedrine Toxicity on Functional Connections, Cell Apoptosis, and CREB-Related Proteins in the Prefrontal Cortex of Rhesus Monkeys.
Duan S, Ma Y, Xie L, Zheng L, Huang J, Guo R, Sun Z, Xie Y, Lv J, Lin Z, Ma S. Duan S, et al. Neurotox Res. 2020 Mar;37(3):602-615. doi: 10.1007/s12640-019-00146-3. Epub 2019 Dec 20. Neurotox Res. 2020. PMID: 31858422
The mechanism of ephedrine toxicity is still unclear. To explore the possible neural mechanisms of ephedrine toxicity, this study established a non-human primate model of ephedrine exposure, analyzed the functional connectivity changes in its pr …
The mechanism of ephedrine toxicity is still unclear. To explore the possible neural mechanisms of ephedrine toxicit …
Ephedrae herba: A comprehensive review of its traditional uses, phytochemistry, pharmacology, and toxicology.
Zheng Q, Mu X, Pan S, Luan R, Zhao P. Zheng Q, et al. J Ethnopharmacol. 2023 May 10;307:116153. doi: 10.1016/j.jep.2023.116153. Epub 2023 Jan 11. J Ethnopharmacol. 2023. PMID: 36641108 Review.
Ephedrae herba possesses multiple pharmacological activities, including diuretic effect, anti-allergic effect, blood pressure regulatory, anti-inflammatory effect, anti-oxidation effect and anti-viral effects. Ephedrine hydrochloride and pseudoephedrine hydrochlo …
Ephedrae herba possesses multiple pharmacological activities, including diuretic effect, anti-allergic effect, blood pressure regulatory, an …
Aqueous chlorination of ephedrine: Kinetic, reaction mechanism and toxicity assessment.
Zhang H, Guo C, Lv J, Hou S, Zhang Y, Gao J, Xu J. Zhang H, et al. Sci Total Environ. 2020 Oct 20;740:140146. doi: 10.1016/j.scitotenv.2020.140146. Epub 2020 Jun 12. Sci Total Environ. 2020. PMID: 32563881
The reaction mechanism involved in the EPH degradation included dehydration, hydroxylation, deamination and demethylation. Toxicity assays by V. qinghaiensis sp. nov proved that the EPH transformation products were much more toxic than the parent compound. Results i …
The reaction mechanism involved in the EPH degradation included dehydration, hydroxylation, deamination and demethylation. Toxicity a …
Natural Sympathomimetic Drugs: From Pharmacology to Toxicology.
Costa VM, Grando LGR, Milandri E, Nardi J, Teixeira P, Mladěnka P, Remião F, On Behalf Of The Oemonom. Costa VM, et al. Biomolecules. 2022 Nov 30;12(12):1793. doi: 10.3390/biom12121793. Biomolecules. 2022. PMID: 36551221 Free PMC article. Review.
., tyramine, tryptamine, histamine and octopamine), illicit drugs (e.g., ephedrine, cathinone, and cocaine), or even caffeine and synephrine. ...Although synthetic sympathomimetic agents are mostly seen as toxic, natural sympathomimetic agents are considered more co …
., tyramine, tryptamine, histamine and octopamine), illicit drugs (e.g., ephedrine, cathinone, and cocaine), or even caffeine and syn …
Toxicity as prime selection criterion among SARS-active herbal medications.
Oesch F, Oesch-Bartlomowicz B, Efferth T. Oesch F, et al. Phytomedicine. 2021 May;85:153476. doi: 10.1016/j.phymed.2021.153476. Epub 2021 Jan 28. Phytomedicine. 2021. PMID: 33593628 Free PMC article. Review.
We rank these medicines according to their toxicity versus safety as basis for preferential rapid research on their potential in the treatment of COVID-19. ...Glycyrrhiza spec. and Panax ginseng are ranked in second priority and ephedrine-free Herba Ephedrae extract …
We rank these medicines according to their toxicity versus safety as basis for preferential rapid research on their potential in the …
Toxicity of amphetamines: an update.
Carvalho M, Carmo H, Costa VM, Capela JP, Pontes H, Remião F, Carvalho F, Bastos Mde L. Carvalho M, et al. Arch Toxicol. 2012 Aug;86(8):1167-231. doi: 10.1007/s00204-012-0815-5. Epub 2012 Mar 6. Arch Toxicol. 2012. PMID: 22392347 Review.
Although amphetamines are widely acknowledged as synthetic drugs, of which amphetamine, methamphetamine, and 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) are well-known examples, humans have used natural amphetamines for several millenniums, through the consumption of amphet …
Although amphetamines are widely acknowledged as synthetic drugs, of which amphetamine, methamphetamine, and 3,4-methylenedioxymethamphetami …
Toxicity of over-the-counter stimulants.
Pentel P. Pentel P. JAMA. 1984 Oct 12;252(14):1898-903. JAMA. 1984. PMID: 6471321
Over-the-counter stimulants (phenylpropanolamine hydrochloride, ephedrine, pseudoephedrine, caffeine) are used widely as decongestants, anorectic agents, amphetamine substitutes, and "legal stimulants." ...Toxic reactions from caffeine are characterized by ag …
Over-the-counter stimulants (phenylpropanolamine hydrochloride, ephedrine, pseudoephedrine, caffeine) are used widely as decon …
Ephedra-associated cardiomyopathy.
Naik SD, Freudenberger RS. Naik SD, et al. Ann Pharmacother. 2004 Mar;38(3):400-3. doi: 10.1345/aph.1D408. Epub 2004 Jan 23. Ann Pharmacother. 2004. PMID: 14742827
Both of these cases have been reported to MedWatch. DISCUSSION: Ephedrine is a potent sympathomimetic agent with direct and indirect effects on adrenergic receptors to cause increases in heart rate, blood pressure, cardiac output, and vascular resistance. The adverse effec …
Both of these cases have been reported to MedWatch. DISCUSSION: Ephedrine is a potent sympathomimetic agent with direct and indirect …
284 results