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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 2
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1,447 results

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Page 1
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis.
Wang Y, Nakayama M, Pitulescu ME, Schmidt TS, Bochenek ML, Sakakibara A, Adams S, Davy A, Deutsch U, Lüthi U, Barberis A, Benjamin LE, Mäkinen T, Nobes CD, Adams RH. Wang Y, et al. Nature. 2010 May 27;465(7297):483-6. doi: 10.1038/nature09002. Nature. 2010. PMID: 20445537
Here we show with genetic experiments in mouse and zebrafish that ephrin-B2, a transmembrane ligand for Eph receptor tyrosine kinases, promotes sprouting behaviour and motility in the angiogenic endothelium. We link this pro-angiogenic function to a crucial r …
Here we show with genetic experiments in mouse and zebrafish that ephrin-B2, a transmembrane ligand for Eph receptor ty …
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry.
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS. Zhang H, et al. Nat Microbiol. 2018 Feb;3(2):1-8. doi: 10.1038/s41564-017-0080-8. Epub 2018 Jan 1. Nat Microbiol. 2018. PMID: 29292383
To understand the mechanisms through which EBV infects epithelial cells, we integrated microarray and RNA interference screen analyses and found that Ephrin receptor A2 (EphA2) is important for EBV entry into the epithelial cells. EphA2 short interfering RNA knockdo …
To understand the mechanisms through which EBV infects epithelial cells, we integrated microarray and RNA interference screen analyses and f …
Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology.
Madasu C, Liao Z, Parks SE, Sharma KL, Bohren KM, Ye Q, Li F, Palaniappan M, Tan Z, Yuan F, Creighton CJ, Tang S, Masand RP, Guan X, Young DW, Monsivais D, Matzuk MM. Madasu C, et al. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2322934121. doi: 10.1073/pnas.2322934121. Epub 2024 May 3. Proc Natl Acad Sci U S A. 2024. PMID: 38701119 Free PMC article.
EPH receptors (EPHs), the largest family of tyrosine kinases, phosphorylate downstream substrates upon binding of ephrin cell surface-associated ligands. ...Kinome profiling revealed that CDD-2693 bound to most EPH family and SRC …
EPH receptors (EPHs), the largest family of tyrosine kinases, phosphorylate downstream substrates upon binding o …
NMR resonance assignment of a ligand-binding domain of ephrin receptor A2.
Mineev KS, Gande SL, Linhard V, Moghaddam SK, Schwalbe H. Mineev KS, et al. Biomol NMR Assign. 2025 Jun;19(1):23-28. doi: 10.1007/s12104-024-10211-4. Epub 2024 Dec 19. Biomol NMR Assign. 2025. PMID: 39695021 Free PMC article.
Ephrin receptor A2 (EphA2), in particular, is overexpressed in a variety of cancers and is a proven target for anti-cancer drugs. The N-terminal ligand-binding domain of ephrin receptors is responsible for the recognition of their ligands, ephri …
Ephrin receptor A2 (EphA2), in particular, is overexpressed in a variety of cancers and is a proven target for anti-cancer dru …
Structural Role of Conformational Heterogeneity and Juxtamembrane Regions in the Ephrin A1 Interactions With the EphA2 Receptor Ligand-binding Domain.
Mineev KS, Gande SL, Wenzel A, Linhard V, Andrews-Clark H, Witt K, Köster S, Segarra M, McDowell MA, Acker-Palmer A, Schwalbe H. Mineev KS, et al. J Mol Biol. 2025 Dec 15;437(24):169454. doi: 10.1016/j.jmb.2025.169454. Epub 2025 Sep 23. J Mol Biol. 2025. PMID: 40998111 Free article.
Ephrin growth factors are attached to the membrane by either GPI-anchor or transmembrane domains and are known to signal bi-directionally: cells, expressing the ephrins experience the downstream signaling in response to ephrin recognition by their receptor, …
Ephrin growth factors are attached to the membrane by either GPI-anchor or transmembrane domains and are known to signal bi-direction …
Interferon-induced transmembrane protein-1 competitively blocks Ephrin receptor A2-mediated Epstein-Barr virus entry into epithelial cells.
Yang Y, Ding T, Cong Y, Luo X, Liu C, Gong T, Zhao M, Zheng X, Li C, Zhang Y, Zhou J, Ni C, Zhang X, Ji Z, Wu T, Yang S, Zhou Q, Wu D, Gong X, Zheng Q, Li X. Yang Y, et al. Nat Microbiol. 2024 May;9(5):1256-1270. doi: 10.1038/s41564-024-01659-0. Epub 2024 Apr 22. Nat Microbiol. 2024. PMID: 38649412 Free PMC article.
Epstein-Barr virus (EBV) can infect both B cells and epithelial cells (ECs), causing diseases such as mononucleosis and cancer. It enters ECs via Ephrin receptor A2 (EphA2). The function of interferon-induced transmembrane protein-1 (IFITM1) in EBV infection of ECs …
Epstein-Barr virus (EBV) can infect both B cells and epithelial cells (ECs), causing diseases such as mononucleosis and cancer. It enters EC …
Ephrin-A binding and EphA receptor expression delineate the matrix compartment of the striatum.
Janis LS, Cassidy RM, Kromer LF. Janis LS, et al. J Neurosci. 1999 Jun 15;19(12):4962-71. doi: 10.1523/JNEUROSCI.19-12-04962.1999. J Neurosci. 1999. PMID: 10366629 Free PMC article.
Ephrin-A1 and ephrin-A4 selectively bind to EphA receptors on neurons restricted to the matrix compartment. ...In contrast, ephrin-A2, ephrin-A3, and ephrin-A5 exhibit a different mosaic binding pattern that appears to define a sub …
Ephrin-A1 and ephrin-A4 selectively bind to EphA receptors on neurons restricted to the matrix compartment. ...In contr …
Eph receptor signaling complexes in the plasma membrane.
Pasquale EB. Pasquale EB. Trends Biochem Sci. 2024 Dec;49(12):1079-1096. doi: 10.1016/j.tibs.2024.10.002. Epub 2024 Nov 12. Trends Biochem Sci. 2024. PMID: 39537538 Free PMC article. Review.
Upon ephrin binding, Eph receptors assemble into oligomers that can further aggregate into large complexes. Eph receptors also mediate ephrin-independent signaling through interplay with intracellular kinases or other cell-surface …
Upon ephrin binding, Eph receptors assemble into oligomers that can further aggregate into large complexes. E …
Ephrin and Eph receptor signaling in female reproductive physiology and pathology .
Adu-Gyamfi EA, Czika A, Liu TH, Gorleku PN, Fondjo LA, Djankpa FT, Ding YB, Wang YX. Adu-Gyamfi EA, et al. Biol Reprod. 2021 Jan 4;104(1):71-82. doi: 10.1093/biolre/ioaa171. Biol Reprod. 2021. PMID: 32940657 Review.
Ephrins are ligands of Eph receptors (Ephs); both of which are sorted into two classes, A and B. There are five types of ephrin-As (ephrin-A1-5) and three types of ephrin-Bs (ephrin-B1-3). Also, there are 10 types of EphAs (EphA1-10) and …
Ephrins are ligands of Eph receptors (Ephs); both of which are sorted into two classes, A and B. There are five types of ep …
Binding and function of phosphotyrosines of the Ephrin A2 (EphA2) receptor using synthetic sterile alpha motif (SAM) domains.
Borthakur S, Lee H, Kim S, Wang BC, Buck M. Borthakur S, et al. J Biol Chem. 2014 Jul 11;289(28):19694-703. doi: 10.1074/jbc.M114.567602. Epub 2014 May 13. J Biol Chem. 2014. PMID: 24825902 Free PMC article.
The sterile alpha motif (SAM) domain of the ephrin receptor tyrosine kinase, EphA2, undergoes tyrosine phosphorylation, but the effect of phosphorylation on the structure and interactions of the receptor is unknown. ...However, phosphorylation at Tyr(921) and …
The sterile alpha motif (SAM) domain of the ephrin receptor tyrosine kinase, EphA2, undergoes tyrosine phosphorylation, but th …
1,447 results