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Recent advances on physiological functions and biotechnological production of epilactose.
Mu W, Li Q, Fan C, Zhou C, Jiang B. Mu W, et al. Appl Microbiol Biotechnol. 2013 Mar;97(5):1821-7. doi: 10.1007/s00253-013-4687-2. Epub 2013 Jan 15. Appl Microbiol Biotechnol. 2013. PMID: 23318840 Review.
Epilactose (4-O-beta-D-galactopyranosyl-D-mannose), an epimer of lactose, is a rare disaccharide existing extremely small quantities in heat-treated milk, in which epilactose is produced by non-enzymatic catalysis from lactose. ...In addition, the biochemical proper
Epilactose (4-O-beta-D-galactopyranosyl-D-mannose), an epimer of lactose, is a rare disaccharide existing extremely small quantities
Epilactose as a Promising Butyrate-Promoter Prebiotic via Microbiota Modulation.
Cardoso BB, Amorim C, Franco-Duarte R, Alves JI, Barbosa SG, Silvério SC, Rodrigues LR. Cardoso BB, et al. Life (Basel). 2024 May 18;14(5):643. doi: 10.3390/life14050643. Life (Basel). 2024. PMID: 38792663 Free PMC article.
Epilactose is a disaccharide composed of galactose and mannose, and it is currently considered an "under development" prebiotic. ...The production of several metabolites (lactate, short-chain fatty acids, and gases) confirmed the prebiotic properties of epilactose.
Epilactose is a disaccharide composed of galactose and mannose, and it is currently considered an "under development" prebiotic. ...T
Prebiotic properties of epilactose.
Watanabe J, Nishimukai M, Taguchi H, Senoura T, Hamada S, Matsui H, Yamamoto T, Wasaki J, Hara H, Ito S. Watanabe J, et al. J Dairy Sci. 2008 Dec;91(12):4518-26. doi: 10.3168/jds.2008-1367. J Dairy Sci. 2008. PMID: 19038926 Free article.
In addition, oral administration of epilactose did not elevate the plasma glucose concentration in ddY mice. These results clearly indicate that epilactose is a promising prebiotic. We also showed that cellobiose 2-epimerase converted lactose in cow milk and a spray …
In addition, oral administration of epilactose did not elevate the plasma glucose concentration in ddY mice. These results clearly in …
Epilactose production by 2 cellobiose 2-epimerases in natural milk.
Krewinkel M, Gosch M, Rentschler E, Fischer L. Krewinkel M, et al. J Dairy Sci. 2014;97(1):155-61. doi: 10.3168/jds.2013-7389. Epub 2013 Nov 7. J Dairy Sci. 2014. PMID: 24210487 Free article.
The enzymes showed different operational stabilities over a 24-h time-course. A conversion yield of about 30 to 33% epilactose was achieved with both enzymes. No side products were detected other than epilactose. Therefore, CE may introduce an added value for partic …
The enzymes showed different operational stabilities over a 24-h time-course. A conversion yield of about 30 to 33% epilactose was ac …
Effects of epilactose on calcium absorption and serum lipid metabolism in rats.
Nishimukai M, Watanabe J, Taguchi H, Senoura T, Hamada S, Matsui H, Yamamoto T, Wasaki J, Hara H, Ito S. Nishimukai M, et al. J Agric Food Chem. 2008 Nov 12;56(21):10340-5. doi: 10.1021/jf801556m. Epub 2008 Oct 7. J Agric Food Chem. 2008. PMID: 18837503
Epilactose also increased the calcium absorption in everted small intestinal sacs. ...Cecal microbes may efficiently utilize epilactose and contribute to these biological activities....
Epilactose also increased the calcium absorption in everted small intestinal sacs. ...Cecal microbes may efficiently utilize epila
Supplemental epilactose prevents metabolic disorders through uncoupling protein-1 induction in the skeletal muscle of mice fed high-fat diets.
Murakami Y, Ojima-Kato T, Saburi W, Mori H, Matsui H, Tanabe S, Suzuki T. Murakami Y, et al. Br J Nutr. 2015 Dec 14;114(11):1774-83. doi: 10.1017/S0007114515003505. Epub 2015 Sep 23. Br J Nutr. 2015. PMID: 26395755
Obesity is one of the major health problems throughout the world. The present study investigated the preventive effect of epilactose--a rare non-digestible disaccharide--on obesity and metabolic disorders in mice fed high-fat (HF) diets. Feeding with HF diets increased bod …
Obesity is one of the major health problems throughout the world. The present study investigated the preventive effect of epilactose- …
Enzymatic production of lactulose and epilactose in milk.
Rentschler E, Schuh K, Krewinkel M, Baur C, Claaßen W, Meyer S, Kuschel B, Stressler T, Fischer L. Rentschler E, et al. J Dairy Sci. 2015 Oct;98(10):6767-75. doi: 10.3168/jds.2015-9900. Epub 2015 Aug 5. J Dairy Sci. 2015. PMID: 26254523 Free article.
At 50C, 2 highly different CsCE amounts were investigated for the time course of formation of lactulose and epilactose. The conversion of milk lactose (initial lactose content of 48.5 2.1 g/L) resulted in a final yield of 57.7% (28.0 g/L) lactulose and 15.5% (7.49 g/L) …
At 50C, 2 highly different CsCE amounts were investigated for the time course of formation of lactulose and epilactose. The conversio …
Identification of a thermostable cellobiose 2-epimerase from Caldicellulosiruptor sp. Rt8.B8 and production of epilactose using Bacillus subtilis.
Liangfei L, Yafeng Z, Kai X, Zheng X. Liangfei L, et al. J Sci Food Agric. 2022 Jan 15;102(1):85-94. doi: 10.1002/jsfa.11333. Epub 2021 Jun 4. J Sci Food Agric. 2022. PMID: 34031874
BACKGROUND: Epilactose, a potential prebiotics, was derived from lactose through enzymatic catalysis. ...CONCLUSION: Our study shed light on the efficient production of epilactose using a food-grade host expressing a novel CE enzyme. Moreover, an efficient and low-c …
BACKGROUND: Epilactose, a potential prebiotics, was derived from lactose through enzymatic catalysis. ...CONCLUSION: Our study shed l …
Novel cellobiose 2-epimerases for the production of epilactose from milk ultrafiltrate containing lactose.
Krewinkel M, Kaiser J, Merz M, Rentschler E, Kuschel B, Hinrichs J, Fischer L. Krewinkel M, et al. J Dairy Sci. 2015 Jun;98(6):3665-78. doi: 10.3168/jds.2015-9411. Epub 2015 Apr 8. J Dairy Sci. 2015. PMID: 25864053 Free article.
In the continuous EMR process, the epilactose yield in the product stream was lower, at 18.5%. However, the enzyme productivity was approximately 6 times higher because the continuous epilactose formation was carried out for about 6 d without further addition of bio …
In the continuous EMR process, the epilactose yield in the product stream was lower, at 18.5%. However, the enzyme productivity was a …
Construction of an enzymatic route using a food-grade recombinant Bacillus subtilis for the production and purification of epilactose from lactose.
Chen Q, He W, Yan X, Zhang T, Jiang B, Stressler T, Fischer L, Mu W. Chen Q, et al. J Dairy Sci. 2018 Mar;101(3):1872-1882. doi: 10.3168/jds.2017-12936. Epub 2017 Dec 28. J Dairy Sci. 2018. PMID: 29290443 Free article.
Many attempts have been made to convert the lactose to high value-added products, including epilactose. Epilactose is a valuable prebiotic and can be epimerized from lactose with cellobiose 2-epimerase (CEase). ...In addition, an enzymatic route including degradatio …
Many attempts have been made to convert the lactose to high value-added products, including epilactose. Epilactose is a valuab …
43 results