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Cross-Reactive Immunity among Five Medically Important Mosquito-Borne Flaviviruses Related to Human Diseases.
Hou B, Chen H, Gao N, An J. Hou B, et al. Viruses. 2022 Jun 2;14(6):1213. doi: 10.3390/v14061213. Viruses. 2022. PMID: 35746683 Free PMC article. Review.
The antibody-dependent enhancement generated by cross-reactive immune responses against different serotypes of dengue virus makes the development of the dengue fever vaccine a bottleneck. It has been proposed that the cross-reactive immunity elicited by prior …
The antibody-dependent enhancement generated by cross-reactive immune responses against different serotypes of dengue virus ma …
Cross-Protection Against Four Serotypes of Dengue Virus in Mice Conferred by a Zika DNA Vaccine.
Wang R, Gao N, Li Y, Fan D, Zhen Z, Feng K, Chen H, An J. Wang R, et al. Front Cell Infect Microbiol. 2019 May 8;9:147. doi: 10.3389/fcimb.2019.00147. eCollection 2019. Front Cell Infect Microbiol. 2019. PMID: 31139577 Free PMC article.
Both Zika virus (ZIKV) and four serotypes of dengue virus (DENV1-4) are antigenically related mosquito-borne flaviviruses that co-circulate in overlapping geographic distributions. ...Our results demonstrate a novel approach for design and development of safe …
Both Zika virus (ZIKV) and four serotypes of dengue virus (DENV1-4) are antigenically related mosquito-borne flavivirus …
miR-223 inhibits dengue virus replication by negatively regulating the microtubule-destabilizing protein STMN1 in EAhy926 cells.
Wu N, Gao N, Fan D, Wei J, Zhang J, An J. Wu N, et al. Microbes Infect. 2014 Nov;16(11):911-22. doi: 10.1016/j.micinf.2014.08.011. Epub 2014 Aug 30. Microbes Infect. 2014. PMID: 25181337 Free PMC article.
The pathogenesis of dengue virus (DENV) infection is not completely understood. Endothelial cells may act as a target of the virus and be involved in disease pathogenesis. ...
The pathogenesis of dengue virus (DENV) infection is not completely understood. Endothelial cells may act as a target of the …
Effective Protection Induced by a Monovalent DNA Vaccine against Dengue Virus (DV) Serotype 1 and a Bivalent DNA Vaccine against DV1 and DV2 in Mice.
Zheng X, Chen H, Wang R, Fan D, Feng K, Gao N, An J. Zheng X, et al. Front Cell Infect Microbiol. 2017 May 12;7:175. doi: 10.3389/fcimb.2017.00175. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 28553618 Free PMC article.
Dengue virus (DV) is the causal pathogen of dengue fever, which is one of the most rapidly spread mosquito-borne disease worldwide and has become a severe public health problem. ...This study sheds new light on developing a dengue tetravalent DNA vacci …
Dengue virus (DV) is the causal pathogen of dengue fever, which is one of the most rapidly spread mosquito-borne diseas …
Long-Term Protection Elicited by a DNA Vaccine Candidate Expressing the prM-E Antigen of Dengue Virus Serotype 3 in Mice.
Feng K, Zheng X, Wang R, Gao N, Fan D, Sheng Z, Zhou H, Chen H, An J. Feng K, et al. Front Cell Infect Microbiol. 2020 Mar 17;10:87. doi: 10.3389/fcimb.2020.00087. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32257963 Free PMC article.
Dengue virus (DENV) is the causative agent of dengue, and its incidence has increased 30-fold in the past five decades. ...This study shows great promise for the further evaluation of a dengue tetravalent DNA vaccine candidate in large animal models, i …
Dengue virus (DENV) is the causative agent of dengue, and its incidence has increased 30-fold in the past five decades. …
Effect of the Rho GTPase inhibitor-1 on the entry of dengue serotype 2 virus into EAhy926 cells.
Fan D, Wu N, Zhang J, Wang Z, Wang P, Gao N, An J. Fan D, et al. Mol Biol Rep. 2020 Dec;47(12):9739-9747. doi: 10.1007/s11033-020-05980-9. Epub 2020 Nov 16. Mol Biol Rep. 2020. PMID: 33200314
Dengue virus (DV) is the most rapidly spreading arbovirus in the world. Our previous studies indicated that Rac1, a kind of Rho GTPase, was related with the increased vascular permeability in DV infection. ...These results not only contribute to our further understa …
Dengue virus (DV) is the most rapidly spreading arbovirus in the world. Our previous studies indicated that Rac1, a kind of Rh …
Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis.
Sheng ZY, Gao N, Wang ZY, Cui XY, Zhou DS, Fan DY, Chen H, Wang PG, An J. Sheng ZY, et al. Front Cell Infect Microbiol. 2017 Jun 21;7:272. doi: 10.3389/fcimb.2017.00272. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 28680856 Free PMC article.
Flaviviruses including Dengue virus (DENV), Yellow fever virus (YFV), West Nile virus (WNV), and Japanese encephalitis virus (JEV) are global health problems that caused several serious diseases such as fever, hemorrhagic fever, and encephalitis …
Flaviviruses including Dengue virus (DENV), Yellow fever virus (YFV), West Nile virus (WNV), and Japanese enceph …
Japanese encephalitis virus prM-E antigen immunization conferred protection against challenge by four different serotypes of Dengue viruses in mice.
Gao N, Li J, Sheng Z, Chen H, Fan D, Wang P, An J. Gao N, et al. Appl Microbiol Biotechnol. 2019 Jun;103(12):4977-4986. doi: 10.1007/s00253-019-09798-9. Epub 2019 Apr 29. Appl Microbiol Biotechnol. 2019. PMID: 31037380
Dengue virus (DENV) and Japanese encephalitis virus (JEV) are closely related mosquito-borne flaviviruses. ...
Dengue virus (DENV) and Japanese encephalitis virus (JEV) are closely related mosquito-borne flaviviruses. ...
Peptides P4 and P7 derived from E protein inhibit entry of dengue virus serotype 2 via interacting with beta3 integrin.
Cui X, Wu Y, Fan D, Gao N, Ming Y, Wang P, An J. Cui X, et al. Antiviral Res. 2018 Jul;155:20-27. doi: 10.1016/j.antiviral.2018.04.018. Epub 2018 Apr 28. Antiviral Res. 2018. PMID: 29709564
Dengue virus (DENV) infection has become a severe public health problem worldwide. However, there is no specific antiviral drug available yet. ...
Dengue virus (DENV) infection has become a severe public health problem worldwide. However, there is no specific antiviral dru …
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