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Year Number of Results
1973 1
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1988 1
1991 1
1993 1
1996 1
1997 3
1999 2
2001 1
2002 3
2003 1
2004 1
2005 1
2007 4
2008 3
2009 3
2010 1
2011 1
2012 2
2013 1
2014 1
2016 2
2017 1
2018 2
2019 1
2020 6
2021 5
2022 3
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49 results
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Safety and tolerability of the novel 2019 coronavirus disease (COVID-19) vaccines among people with epilepsy (PwE): A cross-sectional study.
Massoud F, Ahmad SF, Hassan AM, Alexander KJ, Al-Hashel J, Arabi M. Massoud F, et al. Seizure. 2021 Nov;92:2-9. doi: 10.1016/j.seizure.2021.08.001. Epub 2021 Aug 6. Seizure. 2021. PMID: 34391030 Free PMC article.
BACKGROUND: People with epilepsy (PwE) were concerned about the safety of the novel 2019 Coronavirus Disease (COVID-19) vaccines. ...METHODS: We administered a questionnaire to PwE, who visited the epilepsy clinic at Ibn Sina Hospital in Kuwait during the first two …
BACKGROUND: People with epilepsy (PwE) were concerned about the safety of the novel 2019 Coronavirus Disease (COVID-19) vaccines. ... …
Klotho ameliorated cognitive deficits in a temporal lobe epilepsy rat model by inhibiting ferroptosis.
Xiang T, Luo X, Zeng C, Li S, Ma M, Wu Y. Xiang T, et al. Brain Res. 2021 Dec 1;1772:147668. doi: 10.1016/j.brainres.2021.147668. Epub 2021 Sep 27. Brain Res. 2021. PMID: 34592245
Cognitive deficits are among the most common comorbidities of temporal lobe epilepsy (TLE). Ferroptosis associated with the accumulation of iron overload-dependent lipid peroxidation produces significant cognitive deficits in TLE. ...
Cognitive deficits are among the most common comorbidities of temporal lobe epilepsy (TLE). Ferroptosis associated with the accumulat …
About gladiators and a sacred disease.
Kattner AA. Kattner AA. Biomed J. 2022 Feb;45(1):1-8. doi: 10.1016/j.bj.2022.03.006. Epub 2022 Mar 23. Biomed J. 2022. PMID: 35339730 Free PMC article.
In this special edition of the Biomedical Journal the reader gains an insight into drug-resistant epilepsy and according treatment approaches involving deep brain stimulation, the ketogenic diet and fecal microbiota transplant. ...We learn about a mechanism that helps Leis …
In this special edition of the Biomedical Journal the reader gains an insight into drug-resistant epilepsy and according treatment ap …
Effect of adenovirus-mediated overexpression of PTEN on brain oxidative damage and neuroinflammation in a rat kindling model of epilepsy.
Wu ZS, Huang WL, Gong SJ. Wu ZS, et al. Chin Med J (Engl). 2019 Nov 5;132(21):2628-2635. doi: 10.1097/CM9.0000000000000496. Chin Med J (Engl). 2019. PMID: 31658159 Free PMC article.
BACKGROUND: Epilepsy is a chronic and severe neurological disorder. Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-deficient mice exhibit learning and memory deficits and spontaneous epilepsy. The aim of this study was to investigate the role of PTE …
BACKGROUND: Epilepsy is a chronic and severe neurological disorder. Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-d …
Axon initial segment dysfunction in epilepsy.
Wimmer VC, Reid CA, So EY, Berkovic SF, Petrou S. Wimmer VC, et al. J Physiol. 2010 Jun 1;588(Pt 11):1829-40. doi: 10.1113/jphysiol.2010.188417. Epub 2010 Apr 7. J Physiol. 2010. PMID: 20375142 Free PMC article. Review.
We review recent evidence that a large number of ion channels associated with epilepsy are enriched at the AIS, making it a 'hotspot' for epileptogenesis. Furthermore, we present novel data on the clustering of GABRgamma2 receptors in the AIS of cortical and hippocampal ne …
We review recent evidence that a large number of ion channels associated with epilepsy are enriched at the AIS, making it a 'hotspot' …
Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES).
Hsieh MY, Lin JJ, Hsia SH, Huang JL, Yeh KW, Chang KW, Lee WI. Hsieh MY, et al. Biomed J. 2020 Jun;43(3):293-304. doi: 10.1016/j.bj.2020.05.007. Epub 2020 May 29. Biomed J. 2020. PMID: 32651134 Free PMC article.
BACKGROUND: Defective human TLR3 signaling causes recurrent and refractory herpes simplex encephalitis/encephalopathy. Children with febrile infection-related epilepsy syndrome with refractory seizures may have defective TLR responses. METHODS: Children with febrile infect …
BACKGROUND: Defective human TLR3 signaling causes recurrent and refractory herpes simplex encephalitis/encephalopathy. Children with febrile …
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy.
Colasante G, Qiu Y, Massimino L, Di Berardino C, Cornford JH, Snowball A, Weston M, Jones SP, Giannelli S, Lieb A, Schorge S, Kullmann DM, Broccoli V, Lignani G. Colasante G, et al. Brain. 2020 Mar 1;143(3):891-905. doi: 10.1093/brain/awaa045. Brain. 2020. PMID: 32129831 Free PMC article.
Epilepsy is a major health burden, calling for new mechanistic insights and therapies. ...Continuous video-EEG telemetry showed that AAV9-mediated delivery of CRISPRa, upon doxycycline administration, decreased spontaneous generalized tonic-clonic seizures in a model of te
Epilepsy is a major health burden, calling for new mechanistic insights and therapies. ...Continuous video-EEG telemetry showed that
Adenovirus-mediated gene transfer to the brain: methodological assessment.
Peltékian E, Parrish E, Bouchard C, Peschanski M, Lisovoski F. Peltékian E, et al. J Neurosci Methods. 1997 Jan;71(1):77-84. doi: 10.1016/s0165-0270(96)00128-8. J Neurosci Methods. 1997. PMID: 9125377 Review.
Taking into account uncertainties concerning the innocuousness of Ad transduction, it may seem unwise to envisage Ad gene therapy for diseases that are not life-threatening and/or benefit from adequate drug or surgical treatments (e.g. Parkinson's disease or epilepsy
Taking into account uncertainties concerning the innocuousness of Ad transduction, it may seem unwise to envisage Ad gene therapy for diseas …
Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy.
O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P, Langer D, O'Connor MJ, Freese A. O'Connor WM, et al. Exp Neurol. 1997 Nov;148(1):167-78. doi: 10.1006/exnr.1997.6658. Exp Neurol. 1997. PMID: 9398459
As a first step in the development of a gene therapy approach to epilepsy, we evaluated the ability of adenovirus vectors to direct the transfer into and expression of a marker gene in human brain slices obtained from patients undergoing surgery for medically intrac …
As a first step in the development of a gene therapy approach to epilepsy, we evaluated the ability of adenovirus vectors to d …
A Step-by-Step Protocol for Optogenetic Kindling.
Cela E, Sjöström PJ. Cela E, et al. Front Neural Circuits. 2020 Jan 29;14:3. doi: 10.3389/fncir.2020.00003. eCollection 2020. Front Neural Circuits. 2020. PMID: 32116570 Free PMC article.
Electrical kindling, repeated brain stimulation eventually resulting in seizures, is widely used as an animal model of epileptogenesis and epilepsy. However, the stimulation electrode used for electric kindling targets unknown neuronal populations and may introduce tissue …
Electrical kindling, repeated brain stimulation eventually resulting in seizures, is widely used as an animal model of epileptogenesis and …
49 results