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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1987 1
1988 1
1991 1
1993 1
1996 1
1997 3
1999 2
2001 1
2002 3
2003 1
2004 1
2005 1
2007 4
2008 3
2009 3
2010 1
2011 1
2012 2
2013 1
2014 1
2016 2
2017 1
2018 2
2019 1
2020 4
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39 results
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Page 1
Reversible splenial lesion syndrome in children: Retrospective study and summary of case series.
Chen WX, Liu HS, Yang SD, Zeng SH, Gao YY, Du ZH, Li XJ, Lin HS, Liang HC, Mai JN. Chen WX, et al. Brain Dev. 2016 Nov;38(10):915-927. doi: 10.1016/j.braindev.2016.04.011. Epub 2016 Aug 30. Brain Dev. 2016. PMID: 27591118 Review.
RESULTS: 16 episodes of RESLES occurring in 15 Chinese children were analyzed, with 13 episodes having MERS and 3 episodes with epilepsy. 10 episodes were associated with various pathogens including rotavirus (n=5), adenovirus (n=1), influenza A (n=1), mycoplasma (n …
RESULTS: 16 episodes of RESLES occurring in 15 Chinese children were analyzed, with 13 episodes having MERS and 3 episodes with epilepsy
Effect of adenovirus-mediated overexpression of PTEN on brain oxidative damage and neuroinflammation in a rat kindling model of epilepsy.
Wu ZS, Huang WL, Gong SJ. Wu ZS, et al. Chin Med J (Engl). 2019 Nov 5;132(21):2628-2635. doi: 10.1097/CM9.0000000000000496. Chin Med J (Engl). 2019. PMID: 31658159 Free PMC article.
BACKGROUND: Epilepsy is a chronic and severe neurological disorder. Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-deficient mice exhibit learning and memory deficits and spontaneous epilepsy. ...METHODS: An adenovirus (Ad)-PTEN vector was co …
BACKGROUND: Epilepsy is a chronic and severe neurological disorder. Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-d …
Ectopic expression of Miro 1 ameliorates seizures and inhibits hippocampal neurodegeneration in a mouse model of pilocarpine epilepsy.
Zhang H, Lian Y, Xie N, Zheng Y. Zhang H, et al. Biochem Cell Biol. 2018 Aug;96(4):468-474. doi: 10.1139/bcb-2017-0102. Epub 2018 Jan 24. Biochem Cell Biol. 2018. PMID: 29365285
Epilepsy is a common disease of the central nervous system. This study aimed to investigate the role of mitochondrial Rho (Miro) 1 in epilepsy, using a mouse model of pilocarpine-induced status epilepticus (SE). ...These findings provide new insights into epileptic
Epilepsy is a common disease of the central nervous system. This study aimed to investigate the role of mitochondrial Rho (Miro) 1 in
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy.
Colasante G, Qiu Y, Massimino L, Di Berardino C, Cornford JH, Snowball A, Weston M, Jones SP, Giannelli S, Lieb A, Schorge S, Kullmann DM, Broccoli V, Lignani G. Colasante G, et al. Brain. 2020 Mar 1;143(3):891-905. doi: 10.1093/brain/awaa045. Brain. 2020. PMID: 32129831 Free PMC article.
Epilepsy is a major health burden, calling for new mechanistic insights and therapies. CRISPR-mediated gene editing shows promise to cure genetic pathologies, although hitherto it has mostly been applied ex vivo. ...Continuous video-EEG telemetry showed that AAV9-mediated
Epilepsy is a major health burden, calling for new mechanistic insights and therapies. CRISPR-mediated gene editing shows promise to
Axon initial segment dysfunction in epilepsy.
Wimmer VC, Reid CA, So EY, Berkovic SF, Petrou S. Wimmer VC, et al. J Physiol. 2010 Jun 1;588(Pt 11):1829-40. doi: 10.1113/jphysiol.2010.188417. Epub 2010 Apr 7. J Physiol. 2010. PMID: 20375142 Free PMC article. Review.
We review recent evidence that a large number of ion channels associated with epilepsy are enriched at the AIS, making it a 'hotspot' for epileptogenesis. ...This article highlights the molecular coincidence of epilepsy mutations at the AIS and reviews pathogenic me …
We review recent evidence that a large number of ion channels associated with epilepsy are enriched at the AIS, making it a 'hotspot' …
Gene Therapy Repairs for the Epileptic Brain: Potential for Treatment and Future Directions.
Ahmad MA, Pottoo FH, Akbar M. Ahmad MA, et al. Curr Gene Ther. 2020;19(6):367-375. doi: 10.2174/1566523220666200131142423. Curr Gene Ther. 2020. PMID: 32003688
Epilepsy is a syndrome specified by frequent seizures and is one of the most prevalent neurological conditions, and that one-third of people of epilepsy are resistant to available drugs. Surgery is supposed to be the main treatment for the remedy of multiple drug-re
Epilepsy is a syndrome specified by frequent seizures and is one of the most prevalent neurological conditions, and that one-third of
Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy.
O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P, Langer D, O'Connor MJ, Freese A. O'Connor WM, et al. Exp Neurol. 1997 Nov;148(1):167-78. doi: 10.1006/exnr.1997.6658. Exp Neurol. 1997. PMID: 9398459
As a first step in the development of a gene therapy approach to epilepsy, we evaluated the ability of adenovirus vectors to direct the transfer into and expression of a marker gene in human brain slices obtained from patients undergoing surgery for medically intrac …
As a first step in the development of a gene therapy approach to epilepsy, we evaluated the ability of adenovirus vectors to d …
[Construction of recombinant adenovirus vector for RNA interference with multidrug resistance MDR1 gene].
Chen L, Feng PM, Yang TH, Tian LY, Cheng XW, Zhou D. Chen L, et al. Sichuan Da Xue Xue Bao Yi Xue Ban. 2007 Nov;38(6):913-7. Sichuan Da Xue Xue Bao Yi Xue Ban. 2007. PMID: 18095585 Chinese.
Next, MDR1 shRNA sequence was cloned to pAdeno-X, a transfer vector of adenovirus, to produce the pAdeno-MDR1, which was then packed and amplified in HEK293 cells. ...CONCLUSION: RNAi adenovirus vector of rat MDR1 gene has been constructed and found its high interfe …
Next, MDR1 shRNA sequence was cloned to pAdeno-X, a transfer vector of adenovirus, to produce the pAdeno-MDR1, which was then packed …
Influenza A infection is an important cause of febrile seizures.
Chiu SS, Tse CY, Lau YL, Peiris M. Chiu SS, et al. Pediatrics. 2001 Oct;108(4):E63. doi: 10.1542/peds.108.4.e63. Pediatrics. 2001. PMID: 11581471
For comparison, records of children of the same age group with influenza A infection in 1997, and with parainfluenza and adenovirus infections between 1996 and 1998 were reviewed. ...However, in hospitalized children, influenza A is associated with a higher incidenc …
For comparison, records of children of the same age group with influenza A infection in 1997, and with parainfluenza and adenovirus
fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior.
Yutsudo N, Kamada T, Kajitani K, Nomaru H, Katogi A, Ohnishi YH, Ohnishi YN, Takase K, Sakumi K, Shigeto H, Nakabeppu Y. Yutsudo N, et al. Neuropsychopharmacology. 2013 Apr;38(5):895-906. doi: 10.1038/npp.2012.260. Epub 2012 Dec 18. Neuropsychopharmacology. 2013. PMID: 23303048 Free PMC article.
Moreover, adenovirus-mediated expression of fosB gene products can promote neural stem cell proliferation. We recently found that fosB-null mice show increased depressive behavior, suggesting impaired neurogenesis in fosB-null mice. ...Microarray analysis revealed that gen …
Moreover, adenovirus-mediated expression of fosB gene products can promote neural stem cell proliferation. We recently found that fos …
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