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Early genetic testing for neonatal epilepsy: When, why, and how?
Novotny EJ Jr. Novotny EJ Jr. Neurology. 2017 Aug 29;89(9):880-881. doi: 10.1212/WNL.0000000000004287. Epub 2017 Jul 21. Neurology. 2017. PMID: 28733342 No abstract available.
Japanese encephalitis virus prM-E antigen immunization conferred protection against challenge by four different serotypes of Dengue viruses in mice.
Gao N, Li J, Sheng Z, Chen H, Fan D, Wang P, An J. Gao N, et al. Appl Microbiol Biotechnol. 2019 Jun;103(12):4977-4986. doi: 10.1007/s00253-019-09798-9. Epub 2019 Apr 29. Appl Microbiol Biotechnol. 2019. PMID: 31037380
Dengue virus (DENV) and Japanese encephalitis virus (JEV) are closely related mosquito-borne flaviviruses. Together, they caused most arthropod-borne diseases in the world. Previously, we had demonstrated that both live attenuated and inactivated JE vaccines …
Dengue virus (DENV) and Japanese encephalitis virus (JEV) are closely related mosquito-borne flaviviruses. Together, they caus …
Wasp Venom Toxins as a Potential Therapeutic Agent.
Dongol Y, Dhananjaya BL, Shrestha RK, Aryal G. Dongol Y, et al. Protein Pept Lett. 2016;23(8):688-98. doi: 10.2174/0929866523666160511151039. Protein Pept Lett. 2016. PMID: 27165407 Review.
Wasp venoms are also a rich source of therapeutically important toxins which includes short cationic peptides, kinins, polyamines and polyDNA viruses, to name a few indentified. Wasp venom cationic peptides, namely mastoparan and its analogs, show a very important potency …
Wasp venoms are also a rich source of therapeutically important toxins which includes short cationic peptides, kinins, polyamines and polyDN …
Viruses and the immune system: their roles in seizure cascade development.
Getts DR, Balcar VJ, Matsumoto I, Müller M, King NJ. Getts DR, et al. J Neurochem. 2008 Mar;104(5):1167-76. doi: 10.1111/j.1471-4159.2007.05171.x. Epub 2008 Jan 17. J Neurochem. 2008. PMID: 18205751 Free article. Review.
Most patients with viral encephalitis will develop some form of seizure during the infectious process, and of those who survive encephalitic disease, approximately 4-20% will develop epilepsy. Arthropod-borne (arbo)viruses are the leading cause of viral encep …
Most patients with viral encephalitis will develop some form of seizure during the infectious process, and of those who survive encephalitic …
Sequence analysis and genomic organization of a new insect iflavirus, Sogatella furcifera honeydew virus 1.
Wu N, Zhang P, Liu W, Cao M, Wang X. Wu N, et al. Arch Virol. 2018 Jul;163(7):2001-2003. doi: 10.1007/s00705-018-3817-7. Epub 2018 Mar 24. Arch Virol. 2018. PMID: 29574590
A novel iflavirus, tentatively named "Sogatella furcifera honeydew virus 1" (SFHV1), discovered through transcriptome sequencing analysis of white-backed planthoppers (Sogatella furcifera) collected in southern China, is described here. The full genome of SFHV1 is 10,837 n …
A novel iflavirus, tentatively named "Sogatella furcifera honeydew virus 1" (SFHV1), discovered through transcriptome sequencing anal …
Nodding syndrome-a new hypothesis and new direction for research.
Colebunders R, Hendy A, Nanyunja M, Wamala JF, van Oijen M. Colebunders R, et al. Int J Infect Dis. 2014 Oct;27:74-7. doi: 10.1016/j.ijid.2014.08.001. Epub 2014 Aug 23. Int J Infect Dis. 2014. PMID: 25181949 Free article.
We hypothesize that blackflies (Diptera: Simuliidae) infected with Onchocerca volvulus microfilariae may also transmit another pathogen. This may be a novel neurotropic virus or an endosymbiont of the microfilariae, which causes not only NS, but also epilepsy withou …
We hypothesize that blackflies (Diptera: Simuliidae) infected with Onchocerca volvulus microfilariae may also transmit another pathogen. Thi …
Heterologous expression of membrane proteins for structural analysis.
Mus-Veteau I. Mus-Veteau I. Methods Mol Biol. 2010;601:1-16. doi: 10.1007/978-1-60761-344-2_1. Methods Mol Biol. 2010. PMID: 20099136
These proteins are involved in numerous diseases, like cancer, cystic fibrosis, epilepsy, hyperinsulinism, heart failure, hypertension and Alzheimer disease. ...
These proteins are involved in numerous diseases, like cancer, cystic fibrosis, epilepsy, hyperinsulinism, heart failure, hypertensio …
Human CHD2 is a chromatin assembly ATPase regulated by its chromo- and DNA-binding domains.
Liu JC, Ferreira CG, Yusufzai T. Liu JC, et al. J Biol Chem. 2015 Jan 2;290(1):25-34. doi: 10.1074/jbc.M114.609156. Epub 2014 Nov 10. J Biol Chem. 2015. PMID: 25384982 Free PMC article.
Small G Rac1 is involved in replication cycle of dengue serotype 2 virus in EAhy926 cells via the regulation of actin cytoskeleton.
Zhang J, Wu N, Gao N, Yan W, Sheng Z, Fan D, An J. Zhang J, et al. Sci China Life Sci. 2016 May;59(5):487-94. doi: 10.1007/s11427-016-5042-5. Epub 2016 Apr 7. Sci China Life Sci. 2016. PMID: 27056258 Free PMC article.
Immunization with electroporation enhances the protective effect of a DNA vaccine candidate expressing prME antigen against dengue virus serotype 2 infection.
Chen H, Zheng X, Wang R, Gao N, Sheng Z, Fan D, Feng K, Liao X, An J. Chen H, et al. Clin Immunol. 2016 Oct;171:41-49. doi: 10.1016/j.clim.2016.08.021. Epub 2016 Aug 28. Clin Immunol. 2016. PMID: 27578400
PURPOSE: We aimed to use the dengue virus (DV) serotype 2 as a proof of principal for testing the efficacy of a DNA vaccine candidate via in vivo electroporation in mice and rabbits prior to the development of a tetravalent vaccine. ...
PURPOSE: We aimed to use the dengue virus (DV) serotype 2 as a proof of principal for testing the efficacy of a DNA vaccine candidate …
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