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The gut microbiome and epilepsy.
Dahlin M, Prast-Nielsen S. Dahlin M, et al. EBioMedicine. 2019 Jun;44:741-746. doi: 10.1016/j.ebiom.2019.05.024. Epub 2019 May 31. EBioMedicine. 2019. PMID: 31160269 Free PMC article. Review.
It has now been shown that the ketogenic diet changes the composition and function of the gut microbiome in epilepsy patients. Studies in mice have demonstrated that the gut microbiota was necessary for the therapeutic effect of the diet and a mechanism of ac …
It has now been shown that the ketogenic diet changes the composition and function of the gut microbiome in epilepsy patients. …
Emerging roles for the intestinal microbiome in epilepsy.
Lum GR, Olson CA, Hsiao EY. Lum GR, et al. Neurobiol Dis. 2020 Feb;135:104576. doi: 10.1016/j.nbd.2019.104576. Epub 2019 Aug 21. Neurobiol Dis. 2020. PMID: 31445165 Free article. Review.
There is emerging evidence that alterations in the gut microbiota are seen in epilepsy and in response to seizure interventions. ...Finally, we assess the open questions in interrogating roles for the microbiome in epilepsy and address the prospect tha …
There is emerging evidence that alterations in the gut microbiota are seen in epilepsy and in response to seizure intervention …
The gut microbiome in epilepsy.
Şafak B, Altunan B, Topçu B, Eren Topkaya A. Şafak B, et al. Microb Pathog. 2020 Feb;139:103853. doi: 10.1016/j.micpath.2019.103853. Epub 2019 Nov 13. Microb Pathog. 2020. PMID: 31730997
The close relationship between epilepsy and autoimmune diseases and the fact that the cause of epilepsy is idiopathic in 60% of cases suggest that intestinal microbiota may play a role in the etiology of epilepsy. ...Our data should be supported by oth …
The close relationship between epilepsy and autoimmune diseases and the fact that the cause of epilepsy is idiopathic in 60% o …
Ketogenic Diet and Epilepsy.
Ułamek-Kozioł M, Czuczwar SJ, Januszewski S, Pluta R. Ułamek-Kozioł M, et al. Nutrients. 2019 Oct 18;11(10):2510. doi: 10.3390/nu11102510. Nutrients. 2019. PMID: 31635247 Free PMC article. Review.
Surgical intervention can lead to control in a selected subset of patients, but still leaves a significant number of patients with uncontrolled seizures. Therefore, in drug-resistant epilepsy, the ketogenic diet proves to be useful. The purpose of this review was to provid …
Surgical intervention can lead to control in a selected subset of patients, but still leaves a significant number of patients with uncontrol …
Crosstalk between the Ketogenic Diet and Epilepsy: From the Perspective of Gut Microbiota.
Fan Y, Wang H, Liu X, Zhang J, Liu G. Fan Y, et al. Mediators Inflamm. 2019 Jun 3;2019:8373060. doi: 10.1155/2019/8373060. eCollection 2019. Mediators Inflamm. 2019. PMID: 31281229 Free PMC article. Review.
Given the association between a range of neurological disorders and changes in the gut microbiota, interest in the gut microbiota has recently increased. In particular, the significant involvement of the autoimmune processes in the development of epilepsy, on …
Given the association between a range of neurological disorders and changes in the gut microbiota, interest in the gut microbiota
Altered composition of the gut microbiome in patients with drug-resistant epilepsy.
Peng A, Qiu X, Lai W, Li W, Zhang L, Zhu X, He S, Duan J, Chen L. Peng A, et al. Epilepsy Res. 2018 Nov;147:102-107. doi: 10.1016/j.eplepsyres.2018.09.013. Epub 2018 Sep 24. Epilepsy Res. 2018. PMID: 30291996
OBJECTIVE: The relationship between the gut microbiota and the central nervous system has been gradually recognized while whether microbiome plays a role in the pathogenesis of drug-resistant epilepsy is still unknown. ...While the gut microbiome compo …
OBJECTIVE: The relationship between the gut microbiota and the central nervous system has been gradually recognized while whether …
Ketogenic dietary therapies for epilepsy and beyond.
deCampo DM, Kossoff EH. deCampo DM, et al. Curr Opin Clin Nutr Metab Care. 2019 Jul;22(4):264-268. doi: 10.1097/MCO.0000000000000565. Curr Opin Clin Nutr Metab Care. 2019. PMID: 31033577 Review.
An exciting new potential mechanism for how the ketogenic diet exerts its antiseizure effects is through changing the composition of the gut microbiome. Lastly, ketogenic diets are being applied to a range of neurological conditions from autism to Alzheimer's diseas …
An exciting new potential mechanism for how the ketogenic diet exerts its antiseizure effects is through changing the composition of the gut …
Can we 'seize' the gut microbiota to treat epilepsy?
De Caro C, Iannone LF, Citraro R, Striano P, De Sarro G, Constanti A, Cryan JF, Russo E. De Caro C, et al. Neurosci Biobehav Rev. 2019 Dec;107:750-764. doi: 10.1016/j.neubiorev.2019.10.002. Epub 2019 Oct 15. Neurosci Biobehav Rev. 2019. PMID: 31626816 Review.
Its alterations may consequently influence all these pathways that contribute to neuronal hyper-excitability and mirrored neuroinflammation in epilepsy and similarly other neurological conditions. Indeed, pre- and clinical studies support the role of the microbiome
Its alterations may consequently influence all these pathways that contribute to neuronal hyper-excitability and mirrored neuroinflammation …
Altered gut microbiome composition in children with refractory epilepsy after ketogenic diet.
Zhang Y, Zhou S, Zhou Y, Yu L, Zhang L, Wang Y. Zhang Y, et al. Epilepsy Res. 2018 Sep;145:163-168. doi: 10.1016/j.eplepsyres.2018.06.015. Epub 2018 Jun 28. Epilepsy Res. 2018. PMID: 30007242
OBJECTIVE: The aim of this study was to investigate the characteristics and composition of intestinal microbiota in children with refractory epilepsy after ketogenic diet (KD) therapy and to explore the bacterial biomarkers related to clinical efficacy. ...CONCLUSIO …
OBJECTIVE: The aim of this study was to investigate the characteristics and composition of intestinal microbiota in children with ref …
Gut Microbiota-brain Axis.
Wang HX, Wang YP. Wang HX, et al. Chin Med J (Engl). 2016 Oct 5;129(19):2373-80. doi: 10.4103/0366-6999.190667. Chin Med J (Engl). 2016. PMID: 27647198 Free PMC article. Review.
RESULTS: It is well-recognized that gut microbiota affects the brain's physiological, behavioral, and cognitive functions although its precise mechanism has not yet been fully understood. ...The microbiome is used to define the composition and functional char …
RESULTS: It is well-recognized that gut microbiota affects the brain's physiological, behavioral, and cognitive functions alth …
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