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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 5
1981 1
1984 2
1985 2
1987 1
1988 2
1989 8
1990 4
1991 1
1992 5
1993 2
1994 3
1995 7
1996 15
1997 7
1998 8
1999 4
2000 4
2001 4
2002 6
2003 9
2004 13
2005 25
2006 27
2007 41
2008 43
2009 36
2010 35
2011 42
2012 60
2013 61
2014 50
2015 80
2016 82
2017 65
2018 71
2019 72
2020 62
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865 results
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A network pharmacology approach to explore active compounds and pharmacological mechanisms of epimedium for treatment of premature ovarian insufficiency.
Zhao H, Shan Y, Ma Z, Yu M, Gong B. Zhao H, et al. Drug Des Devel Ther. 2019 Aug 22;13:2997-3007. doi: 10.2147/DDDT.S207823. eCollection 2019. Drug Des Devel Ther. 2019. PMID: 31692519 Free PMC article.
Epimedium is a common traditional Chinese herbal medicine that is widely used to relieve POI in China. To systematically explore the pharmacological mechanism of epimedium on POI therapy, a network pharmacology approach was conducted at the molecular level. ...RESUL …
Epimedium is a common traditional Chinese herbal medicine that is widely used to relieve POI in China. To systematically explore the …
Pharmacokinetics of Prenylflavonoids following Oral Ingestion of Standardized Epimedium Extract in Humans.
Teo YL, Cheong WF, Cazenave-Gassiot A, Ji S, Logan S, Lee ZXK, Li J, Seng KY, Lee LS, Yong EL. Teo YL, et al. Planta Med. 2019 Mar;85(4):347-355. doi: 10.1055/a-0806-7673. Epub 2018 Dec 6. Planta Med. 2019. PMID: 30522143 Clinical Trial.
Leaves of the Epimedium plant are traditionally consumed for bone health and other indications. The aim of this study was to establish the safety and pharmacokinetics of the metabolites of prenylflavonoids (icariin, icariside I, icariside II, icaritin, and desmethylicariti …
Leaves of the Epimedium plant are traditionally consumed for bone health and other indications. The aim of this study was to establis …
Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model.
Liu H, Xiong Y, Wang H, Yang L, Wang C, Liu X, Wu Z, Li X, Ou L, Zhang R, Zhu X. Liu H, et al. J Ethnopharmacol. 2018 Jul 15;221:126-136. doi: 10.1016/j.jep.2018.04.035. Epub 2018 Apr 26. J Ethnopharmacol. 2018. PMID: 29705515 Free article.
ETHNOPHARMACOLOGICAL RELEVANCE: For the past millennium, water extract from Epimedium (dried leaves of Epimedium brevicornu Maxim.) has been widely used for bone disease therapy in traditional Chinese medicine and has been reported to exhibit salutary effects on ost …
ETHNOPHARMACOLOGICAL RELEVANCE: For the past millennium, water extract from Epimedium (dried leaves of Epimedium brevicornu Ma …
Radioprotective effect of epimedium on neurogenesis and cognition after acute radiation exposure.
Wang SW, Ren BX, Qian F, Luo XZ, Tang X, Peng XC, Huang JR, Tang FR. Wang SW, et al. Neurosci Res. 2019 Aug;145:46-53. doi: 10.1016/j.neures.2018.08.011. Epub 2018 Aug 23. Neurosci Res. 2019. PMID: 30145270
Immunohistochemical study showed that epimedium extract prevented the loss of proliferation cells, newly generated neurons, and interneurons in the hilus, in particular, the subgranular zone of the dentate gyrus. It suggests that herb epimedium may be a promising ra …
Immunohistochemical study showed that epimedium extract prevented the loss of proliferation cells, newly generated neurons, and inter …
Comparison of the Active Compositions between Raw and Processed Epimedium from Different Species.
Zhang H, Wang H, Wei J, Chen X, Sun M, Ouyang H, Hao J, Chang Y, Dou Z, He J. Zhang H, et al. Molecules. 2018 Jul 7;23(7):1656. doi: 10.3390/molecules23071656. Molecules. 2018. PMID: 29986486 Free PMC article.
In the guidance of TCM theory, Epimedium herb is usually processed with lamb oil to increase its efficacy. The contents of active ingredients in different Epimedium are significantly varied, which may derive from their different species, regions and processing metho …
In the guidance of TCM theory, Epimedium herb is usually processed with lamb oil to increase its efficacy. The contents of active ing …
A regiospecific rhamnosyltransferase from Epimedium pseudowushanense catalyzes the 3-O-rhamnosylation of prenylflavonols.
Feng K, Chen R, Xie K, Chen D, Guo B, Liu X, Liu J, Zhang M, Dai J. Feng K, et al. Org Biomol Chem. 2018 Jan 17;16(3):452-458. doi: 10.1039/c7ob02763j. Org Biomol Chem. 2018. PMID: 29265155
Epimedium is used in traditional Chinese medicine and contains flavonol glycosides that exhibit multiple biological activities. ...These studies indicate the significant potential of an enzymatic approach for the rhamnosylation of bioactive flavonoids in Epimedium p …
Epimedium is used in traditional Chinese medicine and contains flavonol glycosides that exhibit multiple biological activities. ...Th …
Epimedium protects steroid-induced avascular necrosis of femoral head in rats by inhibiting autophagy.
Liu S, Huang Y, Wang C, Tian S, Xu Y, Ge J. Liu S, et al. Exp Ther Med. 2018 Dec;16(6):5047-5052. doi: 10.3892/etm.2018.6827. Epub 2018 Oct 3. Exp Ther Med. 2018. PMID: 30542458 Free PMC article.
The epimedium group was given 10 ml/kg ephedra extracting solution containing crude drug with the concentration of 1.5 g/ml daily by gavage. ...There were no significant differences between the control and the epimedium group (P>0.05). Neither between the glucoco …
The epimedium group was given 10 ml/kg ephedra extracting solution containing crude drug with the concentration of 1.5 g/ml daily by …
Transcriptomics and metabonomics of the anti-aging properties of total flavones of Epimedium in relation to lipid metabolism.
Wu B, Xiao X, Li S, Zuo G. Wu B, et al. J Ethnopharmacol. 2019 Jan 30;229:73-80. doi: 10.1016/j.jep.2018.09.039. Epub 2018 Sep 29. J Ethnopharmacol. 2019. PMID: 30278205
ETHNOPHARMACOLOGICAL RELEVANCE: Total flavones of Epimedium (TFE) is the main active ingredient in Herba Epimedii, which is a well-known Chinese herbal medicine that is widely used to treat certain age-related diseases in oriental countries. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Total flavones of Epimedium (TFE) is the main active ingredient in Herba Epimedii, which is a well-kn …
Genetic toxicity of Epimedium koreanum Nakai.
Hwang YH, Yang HJ, Yim NH, Ma JY. Hwang YH, et al. J Ethnopharmacol. 2017 Feb 23;198:87-90. doi: 10.1016/j.jep.2016.11.050. Epub 2016 Dec 1. J Ethnopharmacol. 2017. PMID: 27916587
[Effective components and signaling pathways of Epimedium brevicornumbased on network pharmacology].
Zhang RT, Wu HN, Yu GH, Zhou YL, Jia XB, Feng L. Zhang RT, et al. Zhongguo Zhong Yao Za Zhi. 2018 Dec;43(23):4709-4717. doi: 10.19540/j.cnki.cjcmm.20180905.001. Zhongguo Zhong Yao Za Zhi. 2018. PMID: 30717562 Chinese.
The aim of this paper was to find out the active components of Epimedium brevicornum using network pharmacology, and find the potential targets and mechanisms. ...This laid the foundation for the discovery of the active components of Epimedium and the study on its m …
The aim of this paper was to find out the active components of Epimedium brevicornum using network pharmacology, and find the potenti …
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