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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1911 1
1926 1
1927 1
1928 1
1930 1
1932 1
1933 2
1935 1
1937 1
1939 1
1941 2
1945 4
1946 11
1947 17
1948 20
1949 25
1950 45
1951 35
1952 59
1953 58
1954 40
1955 47
1956 50
1957 48
1958 39
1959 42
1960 41
1961 31
1962 46
1963 102
1964 164
1965 84
1966 127
1967 121
1968 128
1969 125
1970 125
1971 132
1972 138
1973 131
1974 141
1975 210
1976 308
1977 412
1978 483
1979 444
1980 471
1981 477
1982 456
1983 483
1984 501
1985 491
1986 488
1987 418
1988 350
1989 317
1990 313
1991 330
1992 342
1993 279
1994 260
1995 234
1996 220
1997 190
1998 169
1999 177
2000 180
2001 173
2002 141
2003 134
2004 112
2005 141
2006 127
2007 108
2008 106
2009 121
2010 107
2011 102
2012 105
2013 119
2014 96
2015 107
2016 95
2017 85
2018 77
2019 79
2020 79
2021 77
2022 77
2023 61
2024 22

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13,400 results

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Page 1
Ergotamine and nicergoline - facts and myths.
Zajdel P, Bednarski M, Sapa J, Nowak G. Zajdel P, et al. Pharmacol Rep. 2015 Apr;67(2):360-3. doi: 10.1016/j.pharep.2014.10.010. Epub 2014 Oct 30. Pharmacol Rep. 2015. PMID: 25712664 Review.
Although introduction of triptans marginalized use of ergotamine, nicergoline is used in cerebral metabolic-vascular disorders, and dementia. ...In line with the recent data, activation of 5-HT2B receptor by ergot derivatives i.e. ergotamine, methysergide, pergolide …
Although introduction of triptans marginalized use of ergotamine, nicergoline is used in cerebral metabolic-vascular disorders, and d …
Ergotamine and dihydroergotamine: a review.
Bigal ME, Tepper SJ. Bigal ME, et al. Curr Pain Headache Rep. 2003 Feb;7(1):55-62. doi: 10.1007/s11916-003-0011-7. Curr Pain Headache Rep. 2003. PMID: 12525272 Review.
In contrast, rectal ergotamine was found to have higher efficacy (73% headache relief) than rectal sumatriptan (63% headache relief). ...In patients with status migrainous and patients with frequent headache recurrence, ergotamine is still probably useful....
In contrast, rectal ergotamine was found to have higher efficacy (73% headache relief) than rectal sumatriptan (63% headache relief). …
Ergotamine dependency--a review.
Saper JR. Saper JR. Headache. 1987 Sep;27(8):435-8. doi: 10.1111/j.1526-4610.1987.hed2708435.x. Headache. 1987. PMID: 3117735 Review. No abstract available.
Ergotamine and dihydroergotamine: history, pharmacology, and efficacy.
Silberstein SD, McCrory DC. Silberstein SD, et al. Headache. 2003 Feb;43(2):144-66. doi: 10.1046/j.1526-4610.2003.03034.x. Headache. 2003. PMID: 12558771 Review.
Ergotamine and dihydroergotamine share structural similarities with the adrenergic, dopaminergic, and serotonergic neurotransmitters. ...The scientific evidence for efficacy is stronger for dihydroergotamine than for ergotamine. Their wide use is based on long-term …
Ergotamine and dihydroergotamine share structural similarities with the adrenergic, dopaminergic, and serotonergic neurotransmitters. …
Ergotamine: its use in the treatment of migraine and its complications.
Saxena VK, De Deyn PP. Saxena VK, et al. Acta Neurol (Napoli). 1992 Apr;14(2):140-6. Acta Neurol (Napoli). 1992. PMID: 1329442 Review.
It is concluded that ergotamine is an effective and valuable substance in the treatment of acute attacks of migraine. However, ergotamine remains a potentially dangerous substance, its possible side effects being multiple and in some cases very serious. ...
It is concluded that ergotamine is an effective and valuable substance in the treatment of acute attacks of migraine. However, erg …
The pharmacology of ergotamine and dihydroergotamine.
Silberstein SD. Silberstein SD. Headache. 1997;37 Suppl 1:S15-25. Headache. 1997. PMID: 9009470 Review.
Their diversity results from their interaction with multiple receptors, their variable receptor affinity and intrinsic activity, and their variable organ-specific receptor access. Ergotamine tartrate (ET) was one of the first ergot alkaloids to be isolated. Dihydroergotami …
Their diversity results from their interaction with multiple receptors, their variable receptor affinity and intrinsic activity, and their v …
Ergotamine in the acute treatment of migraine: a review and European consensus.
Tfelt-Hansen P, Saxena PR, Dahlöf C, Pascual J, Láinez M, Henry P, Diener H, Schoenen J, Ferrari MD, Goadsby PJ. Tfelt-Hansen P, et al. Brain. 2000 Jan;123 ( Pt 1):9-18. doi: 10.1093/brain/123.1.9. Brain. 2000. PMID: 10611116 Review.
Ergotamine has been used in clinical practice for the acute treatment of migraine for over 50 years, but there has been little agreement on its place in clinical practice. An expert group from Europe reviewed the pre-clinical and clinical data on ergotamine as it re …
Ergotamine has been used in clinical practice for the acute treatment of migraine for over 50 years, but there has been little agreem …
Ergotamine tartrate and dihydroergotamine mesylate: safety profiles.
Lipton RB. Lipton RB. Headache. 1997;37 Suppl 1:S33-41. Headache. 1997. PMID: 9009472 Review.
Ergotamine tartrate (ET) and dihydroergotamine mesylate (DHE) have been widely and effectively used in the treatment of migraine for many decades, although few randomized, controlled clinical trials have been conducted with these compounds. ...
Ergotamine tartrate (ET) and dihydroergotamine mesylate (DHE) have been widely and effectively used in the treatment of migraine for …
Dihydroergotamine, ergotamine, methysergide and sumatriptan - basic science in relation to migraine treatment.
Dahlöf C, Maassen Van Den Brink A. Dahlöf C, et al. Headache. 2012 Apr;52(4):707-14. doi: 10.1111/j.1526-4610.2012.02124.x. Epub 2012 Mar 22. Headache. 2012. PMID: 22444161 Free article. Review.
The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5-HT(1B) , 5-HT(1D) , and 5-HT(1F) receptors. Ergotamine, dihydroergotamine, and methysergide, as well as the "triptan" sumatriptan, ar …
The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5- …
Ergotamine absorption and toxicity.
Orton DA, Richardson RJ. Orton DA, et al. Postgrad Med J. 1982 Jan;58(675):6-11. doi: 10.1136/pgmj.58.675.6. Postgrad Med J. 1982. PMID: 7088766 Free PMC article. Clinical Trial.
In 17 of the studies 0.25 mg ergotamine was given by injection, 6 i.v. and 11 i.m., in 20 studies 2 mg ergotamine was given by mouth, and 4 subjects received 2 mg ergotamine by suppository. Plasma and urinary ergotamine was measured by radio-immunoassa …
In 17 of the studies 0.25 mg ergotamine was given by injection, 6 i.v. and 11 i.m., in 20 studies 2 mg ergotamine was given by …
13,400 results
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