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Page 1
ESM-1 silencing decreased cell survival, migration, and invasion and modulated cell cycle progression in hepatocellular carcinoma.
Kang YH, Ji NY, Lee CI, Lee HG, Kim JW, Yeom YI, Kim DG, Yoon SK, Kim JW, Park PJ, Song EY. Kang YH, et al. Amino Acids. 2011 Mar;40(3):1003-13. doi: 10.1007/s00726-010-0729-6. Epub 2010 Sep 7. Amino Acids. 2011. PMID: 20821239
RT-PCR and Western Blot analysis revealed overexpression of ESM-1 in human HCC liver tissue and in serum from patients with HCC. Sandwich ELISA assay was used for quantitative analysis of ESM-1 in serum. ...Based on our results, we sugges …
RT-PCR and Western Blot analysis revealed overexpression of ESM-1 in human HCC liver tissue and in serum from patients …
EpCAM, Ki67, and ESM1 Predict Hepatocellular Carcinoma Recurrence After Liver Transplantation.
Hemida AS, Taie DM, El-Wahed MMA, Shabaan MI, Tantawy MS, Ehsan NA. Hemida AS, et al. Appl Immunohistochem Mol Morphol. 2023 Oct 1;31(9):596-606. doi: 10.1097/PAI.0000000000001150. Epub 2023 Sep 4. Appl Immunohistochem Mol Morphol. 2023. PMID: 37668411
Little is known regarding use of tissue expression of epithelial cell adhesion molecule (EpCAM) to predict HCC recurrence. This study investigates the role of EpCAM, Ki67, and endothelial-cell-specific molecule-1 (ESM1) as immunohistochemical markers to predict H …
Little is known regarding use of tissue expression of epithelial cell adhesion molecule (EpCAM) to predict HCC recurrence. This study …
Histone lactylation facilitates hepatocellular carcinoma progression by upregulating endothelial cell-specific molecule 1 expression.
Zhao P, Qiao C, Wang J, Zhou Y, Zhang C. Zhao P, et al. Mol Carcinog. 2024 Nov;63(11):2078-2089. doi: 10.1002/mc.23794. Epub 2024 Jul 17. Mol Carcinog. 2024. PMID: 39016629
ChIP assay was performed to explore the interaction between histone lactylation and endothelial cell-specific molecule 1 (ESM1). Additionally, gain-and-loss-of-function assays were conducted to investigate the regulatory role of ESM1 in HCC pathogenesis. ...M …
ChIP assay was performed to explore the interaction between histone lactylation and endothelial cell-specific molecule 1 (ESM1). Addi …
ESM1 as a Marker of Macrotrabecular-Massive Hepatocellular Carcinoma.
Calderaro J, Meunier L, Nguyen CT, Boubaya M, Caruso S, Luciani A, Amaddeo G, Regnault H, Nault JC, Cohen J, Oberti F, Michalak S, Bouattour M, Vilgrain V, Pageaux GP, Ramos J, Barget N, Guiu B, Paradis V, Aubé C, Laurent A, Pawlotsky JM, Ganne-Carrié N, Zucman-Rossi J, Seror O, Ziol M. Calderaro J, et al. Clin Cancer Res. 2019 Oct 1;25(19):5859-5865. doi: 10.1158/1078-0432.CCR-19-0859. Epub 2019 Jul 29. Clin Cancer Res. 2019. PMID: 31358545
In the validation set, sensitivity and specificity of ESM1 for the identification of MTM-HCC were 93% (14/15) and 91% (107/117), respectively. Interobserver agreement for ESM1 assessment was good in both series (Cohen Kappa 0.77 and 0.76). CONCLUSIONS: Using …
In the validation set, sensitivity and specificity of ESM1 for the identification of MTM-HCC were 93% (14/15) and 91% (107/117 …
Serum human endothelial cell-specific molecule-1 (endocan) and vascular endothelial growth factor in cirrhotic HCV patients with hepatocellular carcinoma as predictors of mortality.
Youssef AA, Issa HA, Omar MZ, Behiry EG, Elfallah AA, Hasaneen A, Darwish M, Ibrahim DB. Youssef AA, et al. Clin Exp Gastroenterol. 2018 Nov 23;11:431-438. doi: 10.2147/CEG.S171339. eCollection 2018. Clin Exp Gastroenterol. 2018. PMID: 30538523 Free PMC article.
The serum VEGF and endocan were assessed by ELISA. RESULTS: The mean serum endocan level was 4257.6 847.6 pg/mL in HCC patients, compared to 2099.2 459.6 pg/mL in liver cirrhosis patients without HCC. ...Endocan at cut-off value 2967 pg/ml had h …
The serum VEGF and endocan were assessed by ELISA. RESULTS: The mean serum endocan level was 4257.6 847.6 pg/mL in HCC …
ESM-1 expression in stromal cells is predictive of recurrence after radiofrequency ablation in early hepatocellular carcinoma.
Ziol M, Sutton A, Calderaro J, Barget N, Aout M, Leroy V, Blanc JF, Sturm N, Bioulac-Sage P, Nahon P, Nault JC, Charnaux N, N'kontchou G, Trinchet JC, Delehedde M, Seror O, Beaugrand M, Vicaut E, Ganne-Carrié N. Ziol M, et al. J Hepatol. 2013 Dec;59(6):1264-70. doi: 10.1016/j.jhep.2013.07.030. Epub 2013 Aug 6. J Hepatol. 2013. PMID: 23928407
The 2 independent predictive factors of overall recurrence were serum AFP (HR 1.11 [1.002; 1.22], p=0.045) and ESM-1 expression (HR 1.56 [1.004; 2.43], p=0.048). ESM-1 expression was also an independent predictive factor of early recurrence (HR 1.81 [1 …
The 2 independent predictive factors of overall recurrence were serum AFP (HR 1.11 [1.002; 1.22], p=0.045) and ESM-1 expressio …
[Expression of ESM-1 in hepatocellular carcinoma is associated with angiogenesis and tumor invasion].
Xiang X, Zhao WB, Wang X. Xiang X, et al. Zhonghua Gan Zang Bing Za Zhi. 2009 Sep;17(9):661-4. Zhonghua Gan Zang Bing Za Zhi. 2009. PMID: 19785952 Chinese.
Serum levels of ESM-1 were also measured in the HCC patients and healthy controls by Enzyme-linked immunosorbent assay (ELISA). ...CONCLUSION: The expression of ESM-1 is significantly up-regulated in HCC, suggesting that ESM-1 …
Serum levels of ESM-1 were also measured in the HCC patients and healthy controls by Enzyme-linked immunosorbent assay …
Exploration and validation of a combined immune and metabolism gene signature for prognosis prediction of colorectal cancer.
Xiao Y, Zhang G, Wang L, Liang M. Xiao Y, et al. Front Endocrinol (Lausanne). 2022 Nov 28;13:1069528. doi: 10.3389/fendo.2022.1069528. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36518242 Free PMC article.
METHODS: Gene expression profiling and clinical data of HCC samples was retrieved from the from public datasets. IRGs and MRGs were identified from differential expression analysis. ...A prognostic nomogram based on the four-gene signature exhibited a best predictive perfo …
METHODS: Gene expression profiling and clinical data of HCC samples was retrieved from the from public datasets. IRGs and MRGs were i …
Circulating microRNA 9-3p and serum endocan as potential biomarkers for hepatitis C virus-related hepatocellular carcinoma.
Wahb AMSE, El Kassas M, Khamis AK, Elhelbawy M, Elhelbawy N, Habieb MSE. Wahb AMSE, et al. World J Hepatol. 2021 Nov 27;13(11):1753-1765. doi: 10.4254/wjh.v13.i11.1753. World J Hepatol. 2021. PMID: 34904043 Free PMC article.
AIM: To analyze the levels of miRNA 9-3p and endocan in HCV-infected HCC patients and correlate them with clinicopathological parameters. ...Moreover miRNA 9-3p and endocan performed better than alpha-fetoprotein in discriminating HCC patients from cir …
AIM: To analyze the levels of miRNA 9-3p and endocan in HCV-infected HCC patients and correlate them with clinicopathological …
Is serum endocan a sensitive biomarker for early recurrence of hepatocellular carcinoma after radiofrequency ablation?
Omar SA, Attia NM, Sheir MI, Amer AS, El Shabrawy MM, Hasan BB. Omar SA, et al. Eur J Gastroenterol Hepatol. 2021 Jul 1;33(7):1015-1022. doi: 10.1097/MEG.0000000000002074. Eur J Gastroenterol Hepatol. 2021. PMID: 33867440
More recent studies on HCC showed that the elevated serum endocan level was a predictive factor of recurrence after radiofrequency ablation. ...CONCLUSION: Serum endocan is considered as a prognostic biomarker for tumor recurrence in HCC patients after …
More recent studies on HCC showed that the elevated serum endocan level was a predictive factor of recurrence after radiofrequ …
18 results