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17 results

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Page 1
Endocan: A new marker for cancer and a target for cancer therapy.
Yang J, Yang Q, Yu S, Zhang X. Yang J, et al. Biomed Rep. 2015 May;3(3):279-283. doi: 10.3892/br.2015.438. Epub 2015 Feb 26. Biomed Rep. 2015. PMID: 26137222 Free PMC article.
Endocan, previously known as endothelial cell-specific molecule-1 (ESM-1), was cloned from the human umbilical vein endothelial cell cDNA library. ...In normal tissues, chondroitin sulfate/dermatan sulfate proteoglycan is expressed by endothelial cells (such
Endocan, previously known as endothelial cell-specific molecule-1 (ESM-1), was cloned from the human umbilical vein end
Targeting Endothelial Cell-Specific Molecule 1 Protein in Cancer: A Promising Therapeutic Approach.
Zhang H, Shen YW, Zhang LJ, Chen JJ, Bian HT, Gu WJ, Zhang H, Chen HZ, Zhang WD, Luan X. Zhang H, et al. Front Oncol. 2021 May 24;11:687120. doi: 10.3389/fonc.2021.687120. eCollection 2021. Front Oncol. 2021. PMID: 34109132 Free PMC article. Review.
Endothelial cell-specific molecule 1 (ESM-1), a soluble dermatan sulfate proteoglycan, also known as endocan, serves as a diagnostic and prognostic indicator due to its aberrant expression under pathological conditions, including cancer, sepsis, kid
Endothelial cell-specific molecule 1 (ESM-1), a soluble dermatan sulfate proteoglycan, also known as endocan, serves as …
Biological and clinical implications of endocan in gastric cancer.
Zhao W, Sun M, Li S, Wang Y, Liu J. Zhao W, et al. Tumour Biol. 2014 Oct;35(10):10043-9. doi: 10.1007/s13277-014-2287-0. Epub 2014 Jul 11. Tumour Biol. 2014. PMID: 25012244
Endocan overexpression has been reported to be associated with poor prognosis in various cancer types such as breast cancer, kidney cancer, and lung cancer. ...Endocan promoted gastric cancer cell proliferation. Our findings
Endocan overexpression has been reported to be associated with poor prognosis in various cancer types such as breast cancer
Endocan expression and relationship with survival in human non-small cell lung cancer.
Grigoriu BD, Depontieu F, Scherpereel A, Gourcerol D, Devos P, Ouatas T, Lafitte JJ, Copin MC, Tonnel AB, Lassalle P. Grigoriu BD, et al. Clin Cancer Res. 2006 Aug 1;12(15):4575-82. doi: 10.1158/1078-0432.CCR-06-0185. Clin Cancer Res. 2006. PMID: 16899604
PURPOSE: We evaluated the expression of endocan, a soluble lung- and kidney-selective endothelial cell-specific dermatan sulfate proteoglycan, in non-small cell lung tumors compared with normal lung and studied the significance of high levels of circulating endoc
PURPOSE: We evaluated the expression of endocan, a soluble lung- and kidney-selective endothelial cell-specific dermatan sulfa …
Endocan: a new molecule playing a role in the development of hypertension and chronic kidney disease?
Afsar B, Takir M, Kostek O, Covic A, Kanbay M. Afsar B, et al. J Clin Hypertens (Greenwich). 2014 Dec;16(12):914-6. doi: 10.1111/jch.12440. Epub 2014 Nov 6. J Clin Hypertens (Greenwich). 2014. PMID: 25376269 Free PMC article. Review.
Recently, endocan-formerly known as endothelial cell-specific molecule 1 (ESM-1)--was found to be associated with entities such as cancer, hypertension, renal transplant rejection, and chronic renal failure. ...In the current review, the evidence regar …
Recently, endocan-formerly known as endothelial cell-specific molecule 1 (ESM-1)--was found to be associated with entit …
Clinicopathological correlation of endocan expression and survival in epithelial ovarian cancer.
El Behery MM, Seksaka MA, Ibrahiem MA, Saleh HS, El Alfy Y. El Behery MM, et al. Arch Gynecol Obstet. 2013 Dec;288(6):1371-6. doi: 10.1007/s00404-013-2863-3. Epub 2013 May 25. Arch Gynecol Obstet. 2013. PMID: 23708323
Endocan mRNA is identified as one of the most significant molecular signatures defining a poor prognosis in lung, breast, kidney, and hepatocellular cancer. ...CONCLUSION: Endocan could be a reliable marker to predict the survival in epithelial ovarian
Endocan mRNA is identified as one of the most significant molecular signatures defining a poor prognosis in lung, breast, kidney
ESM-1 Mediates Cell Progression in Clear Cell Renal Cell Carcinoma by Affecting Wnt/beta-Catenin Signalling Pathway.
Liu X, Wang F, Du W, Yang X. Liu X, et al. Arch Esp Urol. 2023 Jun;76(4):290-297. doi: 10.56434/j.arch.esp.urol.20237604.33. Arch Esp Urol. 2023. PMID: 37455528 Free article.
This study explored the critical roles as well as molecular mechanism of ESM-1 in ccRCC progression. METHODS: The ESM-1 expression in ccRCC tissues and cells was measured using Western blot assay. ...CONCLUSIONS: ESM-1 acted as an oncogen …
This study explored the critical roles as well as molecular mechanism of ESM-1 in ccRCC progression. METHODS: The ESM- …
Vascular endocan (ESM-1) is markedly overexpressed in clear cell renal cell carcinoma.
Leroy X, Aubert S, Zini L, Franquet H, Kervoaze G, Villers A, Delehedde M, Copin MC, Lassalle P. Leroy X, et al. Histopathology. 2010 Jan;56(2):180-7. doi: 10.1111/j.1365-2559.2009.03458.x. Histopathology. 2010. PMID: 20102396
AIMS: In kidney cancer, new anti-angiogenic therapies have emerged requiring parameters of effectiveness. ...Reverse transcriptase-polymerase chain reaction study confirmed that endocan levels were strongly increased in RCC. Endocan was also detected b …
AIMS: In kidney cancer, new anti-angiogenic therapies have emerged requiring parameters of effectiveness. ...Reverse transcrip …
Anticancer Effect of Benzimidazole Derivatives, Especially Mebendazole, on Triple-Negative Breast Cancer (TNBC) and Radiotherapy-Resistant TNBC In Vivo and In Vitro.
Choi HS, Ko YS, Jin H, Kang KM, Ha IB, Jeong H, Song HN, Kim HJ, Jeong BK. Choi HS, et al. Molecules. 2021 Aug 24;26(17):5118. doi: 10.3390/molecules26175118. Molecules. 2021. PMID: 34500557 Free PMC article.
In this study, we aimed to evaluate the anticancer effect of benzimidazole derivatives on triple-negative breast cancer (TNBC) and investigate its underlying mechanism of action. Several types of cancer and normal breast cells including MDA-MB-231, radiotherapy-resi …
In this study, we aimed to evaluate the anticancer effect of benzimidazole derivatives on triple-negative breast cancer (TNBC) and in …
Novel predictors of early atherosclerosis in nonalcoholic fatty liver disease.
Abdulaziz BA, Bendary AM, Thabet A, Behery EG, Salah M, Khalil MA, Rashad G. Abdulaziz BA, et al. Clin Exp Hepatol. 2023 Jun;9(2):106-114. doi: 10.5114/ceh.2023.127466. Epub 2023 Jun 5. Clin Exp Hepatol. 2023. PMID: 37502438 Free PMC article.
NAFLD is associated with increased mortality due to cardiovascular disease (CVD) and cancer. The carotid intimal media thickness (CIMT), mean platelet volume (MPV) and endocan level could be markers for generalised atherosclerotic burden and endothelial dysfunction. …
NAFLD is associated with increased mortality due to cardiovascular disease (CVD) and cancer. The carotid intimal media thickness (CIM …
17 results