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84 results

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Page 1
Formononetin Inhibits Mast Cell Degranulation to Ameliorate Compound 48/80-Induced Pseudoallergic Reactions.
Zhou ZW, Zhu XY, Li SY, Lin SE, Zhu YH, Ji K, Chen JJ. Zhou ZW, et al. Molecules. 2023 Jul 7;28(13):5271. doi: 10.3390/molecules28135271. Molecules. 2023. PMID: 37446928 Free PMC article.
We showed previously that FNT inhibits immunoglobulin E (IgE)-dependent mast cell (MC) activation, but the effect of FNT on IgE-independent MC activation is yet unknown. ...We studied the effects of FNT on MC degranulation in vitro with a cell culture …
We showed previously that FNT inhibits immunoglobulin E (IgE)-dependent mast cell (MC) activation, but the effect of FNT on Ig …
Comparison of exercise training and estrogen supplementation on mast cell-mediated doxorubicin-induced cardiotoxicity.
Phungphong S, Kijtawornrat A, Kampaengsri T, Wattanapermpool J, Bupha-Intr T. Phungphong S, et al. Am J Physiol Regul Integr Comp Physiol. 2020 May 1;318(5):R829-R842. doi: 10.1152/ajpregu.00224.2019. Epub 2020 Mar 11. Am J Physiol Regul Integr Comp Physiol. 2020. PMID: 32159365 Free article.
Again, estrogen supplementation and mast cell stabilizer treatment prevented these changes but exercise training did not. Histological analysis indicated that the hyperactivation of cardiac mast cells in ovariectomized rats was augmented by doxo …
Again, estrogen supplementation and mast cell stabilizer treatment prevented these changes but exercise training did no …
Estrogen is an important mediator of mast cell activation in ovarian endometriomas.
Zhu TH, Ding SJ, Li TT, Zhu LB, Huang XF, Zhang XM. Zhu TH, et al. Reproduction. 2018 Jan;155(1):73-83. doi: 10.1530/REP-17-0457. Epub 2017 Oct 26. Reproduction. 2018. PMID: 29074615
Endometriosis is an estrogen-dependent disease. Previous research has shown that abnormal enzymes associated with estrogen (E2) metabolism and an increased number of mast cells (MCs) in endometriomas are implicated in the pathogenesis of endometriosis. …
Endometriosis is an estrogen-dependent disease. Previous research has shown that abnormal enzymes associated with estrogen (E2 …
Estrogen inhibits mast cell chymase release to prevent pressure overload-induced adverse cardiac remodeling.
Li J, Jubair S, Janicki JS. Li J, et al. Hypertension. 2015 Feb;65(2):328-34. doi: 10.1161/HYPERTENSIONAHA.114.04238. Epub 2014 Nov 17. Hypertension. 2015. PMID: 25403608 Free PMC article.
To test the hypothesis that estrogen prevents pressure overload-induced adverse cardiac remodeling by inhibiting mast cell (MC) chymase release, transverse aortic constriction or sham surgery was performed in 7-week-old intact and ovariectomized (OVX) rats. . …
To test the hypothesis that estrogen prevents pressure overload-induced adverse cardiac remodeling by inhibiting mast cell …
TAK1 signaling activity links the mast cell cytokine response and degranulation in allergic inflammation.
Watson CJF, Maguire ARR, Rouillard MM, Crozier RWE, Yousef M, Bruton KM, Fajardo VA, MacNeil AJ. Watson CJF, et al. J Leukoc Biol. 2020 Apr;107(4):649-661. doi: 10.1002/JLB.2A0220-401RRR. Epub 2020 Feb 28. J Leukoc Biol. 2020. PMID: 32108376
We, therefore, interrogated the role of TAK1 in a series of mast cell-mediated responses using IgE-sensitized murine bone marrow-derived mast cells, stimulated with allergen under several TAK1 inhibition strategies. ...Impaired gene expression and near …
We, therefore, interrogated the role of TAK1 in a series of mast cell-mediated responses using IgE-sensitized murine bone marr …
Environmental estrogens induce mast cell degranulation and enhance IgE-mediated release of allergic mediators.
Narita S, Goldblum RM, Watson CS, Brooks EG, Estes DM, Curran EM, Midoro-Horiuti T. Narita S, et al. Environ Health Perspect. 2007 Jan;115(1):48-52. doi: 10.1289/ehp.9378. Environ Health Perspect. 2007. PMID: 17366818 Free PMC article.
The combination of physiologic concentrations of 17beta-estradiol and several concentrations of environmental estrogens had additive effects on mast cell degranulation. Comparison of bone marrow mast cells from ER-alpha-sufficient and ER- …
The combination of physiologic concentrations of 17beta-estradiol and several concentrations of environmental estrogens had additive …
Modulation of cardiac mast cell-mediated extracellular matrix degradation by estrogen.
Chancey AL, Gardner JD, Murray DB, Brower GL, Janicki JS. Chancey AL, et al. Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H316-21. doi: 10.1152/ajpheart.00765.2004. Epub 2005 Feb 18. Am J Physiol Heart Circ Physiol. 2005. PMID: 15722408 Free article.
With the known gender differences in cardiac disease in mind, we sought to examine the effects of chemically induced cardiac mast cell degranulation in isolated, blood-perfused hearts of intact female rats, ovariectomized female rats, and ovariectomized femal …
With the known gender differences in cardiac disease in mind, we sought to examine the effects of chemically induced cardiac mast …
Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways.
Musa I, Wang ZZ, Yang N, Li XM. Musa I, et al. Front Immunol. 2024 Aug 15;15:1427563. doi: 10.3389/fimmu.2024.1427563. eCollection 2024. Front Immunol. 2024. PMID: 39221239 Free PMC article.
Formononetin decreased beta-hexosaminidase release in RBL-2H3 cells and KU812 cells. Formononetin regulates 25 targets in food allergy, 51 in IgE diseases, and 19 in mast cell diseases. ...CONCLUSION: These findings comprehensively present formononetin …
Formononetin decreased beta-hexosaminidase release in RBL-2H3 cells and KU812 cells. Formononetin regulates 25 targets in food …
Mast cell interactions with the nervous system: relationship to mechanisms of disease.
Dines KC, Powell HC. Dines KC, et al. J Neuropathol Exp Neurol. 1997 Jun;56(6):627-40. J Neuropathol Exp Neurol. 1997. PMID: 9184654 Review.
Structural interactions between mast cells and a variety of other cells have been observed, as well as close approximation of mast cells to nerve endings in tissues in which mast cells are especially active. Due to their paracrine …
Structural interactions between mast cells and a variety of other cells have been observed, as well as close approximat …
Mast cell degranulation in rat uterine cervix during pregnancy correlates with expression of vascular endothelial growth factor mRNA and angiogenesis.
Bosquiazzo VL, Ramos JG, Varayoud J, Muñoz-de-Toro M, Luque EH. Bosquiazzo VL, et al. Reproduction. 2007 May;133(5):1045-55. doi: 10.1530/REP-06-0168. Reproduction. 2007. PMID: 17616733
Vascular growth of the uterine cervix during pregnancy is associated with mast cell (MC) degranulation. To better understand the mechanism underlying this process, uterine cervices of intact pregnant rats were dissected and endothelial cell proliferati …
Vascular growth of the uterine cervix during pregnancy is associated with mast cell (MC) degranulation. To better under …
84 results