Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis.
da Costa BR, Pereira TV, Saadat P, Rudnicki M, Iskander SM, Bodmer NS, Bobos P, Gao L, Kiyomoto HD, Montezuma T, Almeida MO, Cheng PS, Hincapié CA, Hari R, Sutton AJ, Tugwell P, Hawker GA, Jüni P.
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BMJ. 2021 Oct 12;375:n2321. doi: 10.1136/bmj.n2321.
BMJ. 2021.
PMID: 34642179
Free PMC article.
Five oral preparations (diclofenac 150 mg/day, etoricoxib 60 and 90 mg/day, and rofecoxib 25 and 50 mg/day) had 99% probability of more pronounced treatment effects than the minimal clinically relevant reduction in pain. ...Oxymorphone 80 mg/day had the highest risk of dro …
Five oral preparations (diclofenac 150 mg/day, etoricoxib 60 and 90 mg/day, and rofecoxib 25 and 50 mg/day) had 99% probability of mo …