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E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and function.
Wei Y, Han S, Wen J, Liao J, Liang J, Yu J, Chen X, Xiang S, Huang Z, Zhang B. Wei Y, et al. J Biomed Sci. 2023 Mar 6;30(1):17. doi: 10.1186/s12929-023-00909-3. J Biomed Sci. 2023. PMID: 36872348 Free PMC article. Review.
Its roles in cancer metastasis, proliferation, oxidative stress response and drug resistance indicate that it is a potential prognostic biomarker, as well as a therapeutic target for cancer treatment. ...The updated molecular mechanisms of ETV5 in cancer biol …
Its roles in cancer metastasis, proliferation, oxidative stress response and drug resistance indicate that it is a potential p …
Proteomic approach to ETV5 during endometrial carcinoma invasion reveals a link to oxidative stress.
Monge M, Colas E, Doll A, Gil-Moreno A, Castellvi J, Diaz B, Gonzalez M, Lopez-Lopez R, Xercavins J, Carreras R, Alameda F, Canals F, Gabrielli F, Reventos J, Abal M. Monge M, et al. Carcinogenesis. 2009 Aug;30(8):1288-97. doi: 10.1093/carcin/bgp119. Epub 2009 May 14. Carcinogenesis. 2009. PMID: 19443906
In addition, we characterized the specific upregulation of the nuclear dehydrogenase/reductase Hep27 as well as its ERM/ETV5-dependent mitochondrial localization. Further functional studies demonstrated a protective role of Hep 27 against apoptosis induced by oxidative …
In addition, we characterized the specific upregulation of the nuclear dehydrogenase/reductase Hep27 as well as its ERM/ETV5-dependen …
Synthetic 8-hydroxydeoxyguanosine inhibited metastasis of pancreatic cancer through concerted inhibitions of ERM and Rho-GTPase.
Park JM, Han YM, Jeong M, Chung MH, Kwon CI, Ko KH, Hahm KB. Park JM, et al. Free Radic Biol Med. 2017 Sep;110:151-161. doi: 10.1016/j.freeradbiomed.2017.06.003. Epub 2017 Jun 8. Free Radic Biol Med. 2017. PMID: 28602912
8-hydroxydeoxyguanosine (8-OHdG) is generated consequent to oxidative stress, but its paradoxical anti-oxidative, anti-inflammatory, and anti-mutagenic effects via Rho-GTPase inhibition were noted in various models of inflammation and cancer. ...
8-hydroxydeoxyguanosine (8-OHdG) is generated consequent to oxidative stress, but its paradoxical anti-oxidative, anti- …