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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1967 1
1968 1
1970 5
1971 1
1972 3
1973 4
1974 1
1975 14
1976 10
1977 9
1978 16
1979 15
1980 15
1981 20
1982 13
1983 21
1984 27
1985 28
1986 30
1987 22
1988 19
1989 22
1990 31
1991 30
1992 17
1993 20
1994 16
1995 14
1996 29
1997 31
1998 28
1999 19
2000 31
2001 28
2002 33
2003 24
2004 19
2005 21
2006 26
2007 25
2008 28
2009 25
2010 26
2011 21
2012 22
2013 29
2014 35
2015 24
2016 39
2017 47
2018 49
2019 57
2020 71
2021 81
2022 72
2023 89
2024 23

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1,372 results

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Page 1
Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases.
Jensen NJ, Wodschow HZ, Nilsson M, Rungby J. Jensen NJ, et al. Int J Mol Sci. 2020 Nov 20;21(22):8767. doi: 10.3390/ijms21228767. Int J Mol Sci. 2020. PMID: 33233502 Free PMC article. Review.
However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain. The brain's utilization of ketones seems to depend mainly on the concentration in the blood, thus many dietary approaches s …
However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for t …
Exogenous Ketone Supplements in Athletic Contexts: Past, Present, and Future.
Evans M, McClure TS, Koutnik AP, Egan B. Evans M, et al. Sports Med. 2022 Dec;52(Suppl 1):25-67. doi: 10.1007/s40279-022-01756-2. Epub 2022 Oct 10. Sports Med. 2022. PMID: 36214993 Free PMC article. Review.
There has been long-standing interest in the development of ingestible forms of ketone bodies that has recently resulted in the commercial availability of exogenous ketone supplements (EKS). These supplements in the form of ketone salts and ketone
There has been long-standing interest in the development of ingestible forms of ketone bodies that has recently resulted in the comme …
β-hydroxybutyrate as an Anti-Aging Metabolite.
Wang L, Chen P, Xiao W. Wang L, et al. Nutrients. 2021 Sep 28;13(10):3420. doi: 10.3390/nu13103420. Nutrients. 2021. PMID: 34684426 Free PMC article. Review.
The ketone bodies, especially beta-hydroxybutyrate (beta-HB), derive from fatty acid oxidation and alternatively serve as a fuel source for peripheral tissues including the brain, heart, and skeletal muscle. beta-HB is currently considered not solely an energy substrate fo …
The ketone bodies, especially beta-hydroxybutyrate (beta-HB), derive from fatty acid oxidation and alternatively serve as a fuel sour …
Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases.
Kovács Z, Brunner B, Ari C. Kovács Z, et al. Nutrients. 2021 Jun 26;13(7):2197. doi: 10.3390/nu13072197. Nutrients. 2021. PMID: 34206738 Free PMC article. Review.
Thus, development of new therapeutic tools to alleviate aging processes and related diseases and to increase life expectancy is a topic of increasing interest. It is widely accepted that ketosis (increased blood ketone body levels, e.g., beta-hydroxybutyrate) can generate …
Thus, development of new therapeutic tools to alleviate aging processes and related diseases and to increase life expectancy is a topic of i …
The Ketogenic Diet in Colorectal Cancer: A Means to an End.
Tamraz M, Al Ghossaini N, Temraz S. Tamraz M, et al. Int J Mol Sci. 2023 Feb 12;24(4):3683. doi: 10.3390/ijms24043683. Int J Mol Sci. 2023. PMID: 36835094 Free PMC article. Review.
The ketogenic diet decreases the amount of available glucose for tumors and shifts to the production of ketone bodies as an alternative energy source for healthy cells. Cancer cells are unable to use the ketone bodies for energy thus depriving them of the energy nee …
The ketogenic diet decreases the amount of available glucose for tumors and shifts to the production of ketone bodies as an alternati …
Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.
Ari C, Murdun C, Koutnik AP, Goldhagen CR, Rogers C, Park C, Bharwani S, Diamond DM, Kindy MS, D'Agostino DP, Kovács Z. Ari C, et al. Nutrients. 2019 Oct 1;11(10):2330. doi: 10.3390/nu11102330. Nutrients. 2019. PMID: 31581549 Free PMC article.
Compliance to KD can be difficult, so alternative therapies that help reduce glucose levels are needed. Exogenous ketones provide an alternative method to elevate blood ketone levels without strict dietary requirements. ...Experimental groups included KD, sta …
Compliance to KD can be difficult, so alternative therapies that help reduce glucose levels are needed. Exogenous ketones prov …
The Ketogenic Diet and Alzheimer's Disease.
Hersant H, Grossberg G. Hersant H, et al. J Nutr Health Aging. 2022;26(6):606-614. doi: 10.1007/s12603-022-1807-7. J Nutr Health Aging. 2022. PMID: 35718870 Free article. Review.
METHODS: The PubMed database was searched for clinical trials and randomized, controlled trials involving the KD or exogenous ketone administration and AD. Key search terms used included "ketogenic diet and Alzheimer's disease," "ketosis and Alzheimer's disease," "M …
METHODS: The PubMed database was searched for clinical trials and randomized, controlled trials involving the KD or exogenous keto
Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation.
Evans M, Cogan KE, Egan B. Evans M, et al. J Physiol. 2017 May 1;595(9):2857-2871. doi: 10.1113/JP273185. Epub 2016 Dec 7. J Physiol. 2017. PMID: 27861911 Free PMC article. Review.
Ketone bodies are oxidised as a fuel source during exercise, are markedly elevated during the post-exercise recovery period, and the ability to utilise ketone bodies is higher in exercise-trained skeletal muscle. ...Initial reports suggest this strategy alters the m
Ketone bodies are oxidised as a fuel source during exercise, are markedly elevated during the post-exercise recovery period, and the
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.
Cheng CW, Biton M, Haber AL, Gunduz N, Eng G, Gaynor LT, Tripathi S, Calibasi-Kocal G, Rickelt S, Butty VL, Moreno-Serrano M, Iqbal AM, Bauer-Rowe KE, Imada S, Ulutas MS, Mylonas C, Whary MT, Levine SS, Basbinar Y, Hynes RO, Mino-Kenudson M, Deshpande V, Boyer LA, Fox JG, Terranova C, Rai K, Piwnica-Worms H, Mihaylova MM, Regev A, Yilmaz ÖH. Cheng CW, et al. Cell. 2019 Aug 22;178(5):1115-1131.e15. doi: 10.1016/j.cell.2019.07.048. Cell. 2019. PMID: 31442404 Free PMC article.
Here we show that, in the mammalian small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), the gene encoding the rate-limiting enzyme in the production of ketone bodies, including beta-hydroxybutyrate (betaOHB), distinguishes self-renewing …
Here we show that, in the mammalian small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), the gene encodi …
1,372 results