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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
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2010 5
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2012 20
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1,653 results

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Filters applied: Abstract, in the last 10 years. Clear all
Page 1
Engineered exosome therapeutics for neurodegenerative diseases.
Saikia B, Dhanushkodi A. Saikia B, et al. Life Sci. 2024 Nov 1;356:123019. doi: 10.1016/j.lfs.2024.123019. Epub 2024 Aug 28. Life Sci. 2024. PMID: 39209250 Free article. Review.
In this review, we have discussed the neuroprotective properties of exosomes derived from adult mesenchymal stem cells, with a special focus on the role of exosomal miRNAs. We also reviewed various strategies to improve exosome production and their content fo …
In this review, we have discussed the neuroprotective properties of exosomes derived from adult mesenchymal stem cells, with a specia …
The biology, function, and biomedical applications of exosomes.
Kalluri R, LeBleu VS. Kalluri R, et al. Science. 2020 Feb 7;367(6478):eaau6977. doi: 10.1126/science.aau6977. Science. 2020. PMID: 32029601 Free PMC article. Review.
Their diverse constituents include nucleic acids, proteins, lipids, amino acids, and metabolites, which can reflect their cell of origin. In various diseases, exosomes offer a window into altered cellular or tissue states, and their detection in biological fluids po …
Their diverse constituents include nucleic acids, proteins, lipids, amino acids, and metabolites, which can reflect their cell of origin. In …
Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases.
Rai S, Ray SK, Kanwar JR, Mukherjee S. Rai S, et al. Mol Cell Neurosci. 2025 Jun;133:104004. doi: 10.1016/j.mcn.2025.104004. Epub 2025 Mar 22. Mol Cell Neurosci. 2025. PMID: 40122271 Review.
Neurodegenerative disorders include Parkinson's disease, spinal cord injury, multiple sclerosis and Alzheimer's disease, cause gradual neuronal loss, protein misfolding, and accumulation, resulting in severe cognitive and movement deficits. ...Advanced engineering approach …
Neurodegenerative disorders include Parkinson's disease, spinal cord injury, multiple sclerosis and Alzheimer's disease, cause gradua …
Dual Role of Exosome in Neurodegenerative Diseases: A Review Study.
Sheykhhasan M, Heidari F, Farsani ME, Azimzadeh M, Kalhor N, Ababzadeh S, Seyedebrahimi R. Sheykhhasan M, et al. Curr Stem Cell Res Ther. 2024;19(6):852-864. doi: 10.2174/1574888X18666230726161035. Curr Stem Cell Res Ther. 2024. PMID: 37496136 Review.
METHODS: The MEDLINE/PubMed database was reviewed for papers written in English and publication dates of recent years, using the search string "Exosome" and "Neurodegenerative diseases." RESULTS: The exosomes have attracted interest as a significant bi …
METHODS: The MEDLINE/PubMed database was reviewed for papers written in English and publication dates of recent years, using the search stri …
Exosomes.
Pegtel DM, Gould SJ. Pegtel DM, et al. Annu Rev Biochem. 2019 Jun 20;88:487-514. doi: 10.1146/annurev-biochem-013118-111902. Annu Rev Biochem. 2019. PMID: 31220978 Review.
Exosome biogenesis is a mechanism of protein quality control, and once released, exosomes have activities as diverse as remodeling the extracellular matrix and transmitting signals and molecules to other cells. This pathway of intercellular vesicle traffic plays imp …
Exosome biogenesis is a mechanism of protein quality control, and once released, exosomes have activities as diverse as remode …
Exploring Exosome-Based Approaches for Early Diagnosis and Treatment of Neurodegenerative Diseases.
Varshney V, Gabble BC, Bishoyi AK, Varma P, Qahtan SA, Kashyap A, Panigrahi R, Nathiya D, Chauhan AS. Varshney V, et al. Mol Neurobiol. 2025 Nov;62(11):14683-14705. doi: 10.1007/s12035-025-05026-w. Epub 2025 May 10. Mol Neurobiol. 2025. PMID: 40347374 Review.
Neurodegenerative diseases (NDs), like Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and Amyotrophic Lateral Sclerosis (ALS), present an increasingly significant global health burden, primarily due to the lack of effective early diag …
Neurodegenerative diseases (NDs), like Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and Amyo …
Exosome Biomarkers Revolutionize Preclinical Diagnosis of Neurodegenerative Diseases and Assessment of Treatment Responses in Clinical Trials.
Kapogiannis D. Kapogiannis D. Adv Exp Med Biol. 2020;1195:149. doi: 10.1007/978-3-030-32633-3_19. Adv Exp Med Biol. 2020. PMID: 32468469 Review.
Alzheimer's disease and other neurodegenerative diseases have long preclinical phases with active and progressively irreversible pathology. ...Neuronal and astrocytic EVs have been implicated in the pathogenesis of several neurodegenerative diseases. G …
Alzheimer's disease and other neurodegenerative diseases have long preclinical phases with active and progressively irreversib …
Protein transmission in neurodegenerative disease.
Peng C, Trojanowski JQ, Lee VM. Peng C, et al. Nat Rev Neurol. 2020 Apr;16(4):199-212. doi: 10.1038/s41582-020-0333-7. Epub 2020 Mar 23. Nat Rev Neurol. 2020. PMID: 32203399 Free PMC article. Review.
Most neurodegenerative diseases are characterized by the intracellular or extracellular aggregation of misfolded proteins such as amyloid-beta and tau in Alzheimer disease, alpha-synuclein in Parkinson disease, and TAR DNA-binding protein 43 in amyotrophic lateral s …
Most neurodegenerative diseases are characterized by the intracellular or extracellular aggregation of misfolded proteins such …
Emerging Role of Genetic Alterations Affecting Exosome Biology in Neurodegenerative Diseases.
Riva P, Battaglia C, Venturin M. Riva P, et al. Int J Mol Sci. 2019 Aug 23;20(17):4113. doi: 10.3390/ijms20174113. Int J Mol Sci. 2019. PMID: 31450727 Free PMC article. Review.
The abnormal deposition of proteins in brain tissue is a common feature of neurodegenerative diseases (NDs) often accompanied by the spread of mutated proteins, causing neuronal toxicity. ...This review aims to summarize the mechanisms underlying exosome biog …
The abnormal deposition of proteins in brain tissue is a common feature of neurodegenerative diseases (NDs) often accompanied …
A Review of the Neuroprotective Properties of Exosomes Derived from Stem Cells and Exosome-Coated Nanoparticles for Treating Neurodegenerative Diseases and Stroke.
Yang YP, Nicol CJB, Chiang MC. Yang YP, et al. Int J Mol Sci. 2025 Apr 21;26(8):3915. doi: 10.3390/ijms26083915. Int J Mol Sci. 2025. PMID: 40332773 Free PMC article. Review.
Neurological diseases, including neurodegenerative disorders and stroke, represent significant medical challenges due to their complexity and the limitations of current treatment approaches. This review explores the potential of stem cell (SC)-derived exosomes …
Neurological diseases, including neurodegenerative disorders and stroke, represent significant medical challenges due to their …
1,653 results