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43,558 results

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Page 1
The Machinery of Exosomes: Biogenesis, Release, and Uptake.
Krylova SV, Feng D. Krylova SV, et al. Int J Mol Sci. 2023 Jan 10;24(2):1337. doi: 10.3390/ijms24021337. Int J Mol Sci. 2023. PMID: 36674857 Free PMC article. Review.
Additionally, delivery of exosomes and exosomal miRNA has already been shown to improve systemic metabolism and inhibit progression of cancer development in mice. However, the subcellular machinery of exosomes, including their biogenesis, release and uptake, …
Additionally, delivery of exosomes and exosomal miRNA has already been shown to improve systemic metabolism and inhibit progre …
Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake.
Kimiz-Gebologlu I, Oncel SS. Kimiz-Gebologlu I, et al. J Control Release. 2022 Jul;347:533-543. doi: 10.1016/j.jconrel.2022.05.027. Epub 2022 May 24. J Control Release. 2022. PMID: 35597405 Review.
Exosomes are nanovesicles with different contents that play a role in various biological and pathological processes. ...For this purpose, methodologies for the large-scale production of exosomes, exosome isolation, exosomal cargo loading, and exosom …
Exosomes are nanovesicles with different contents that play a role in various biological and pathological processes. ...For this purp …
Exosomes in review: A new frontier in CAR-T cell therapies.
Wang JS, Schellenberg SJ, Demeros A, Lin AY. Wang JS, et al. Neoplasia. 2025 Apr;62:101147. doi: 10.1016/j.neo.2025.101147. Epub 2025 Mar 3. Neoplasia. 2025. PMID: 40037165 Free PMC article. Review.
Exosomes are extracellular vehicles that facilitate intra-cellular communication via transport of critical proteins and genetic material. ...Moreover, infusion of CAR exosomes in animal models did not generate cytokine release syndrome. Conversely, there are also no …
Exosomes are extracellular vehicles that facilitate intra-cellular communication via transport of critical proteins and genetic mater …
Exosomes: Multifaceted Messengers in Atherosclerosis.
Wang H, Xie Y, Salvador AM, Zhang Z, Chen K, Li G, Xiao J. Wang H, et al. Curr Atheroscler Rep. 2020 Aug 9;22(10):57. doi: 10.1007/s11883-020-00871-7. Curr Atheroscler Rep. 2020. PMID: 32772195 Review.
To elucidate the role of exosomes in AS and thus provide a new insight into AS therapy, we review recent advances concerning exosome targets and their function in mediating intercellular communication in AS, and expect to provide a reference for novel effective stra …
To elucidate the role of exosomes in AS and thus provide a new insight into AS therapy, we review recent advances concerning exoso …
ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1.
Patwardhan S, Mahadik P, Shetty O, Sen S. Patwardhan S, et al. Biomaterials. 2021 Dec;279:121185. doi: 10.1016/j.biomaterials.2021.121185. Epub 2021 Oct 14. Biomaterials. 2021. PMID: 34808560
Proteomic analysis of exosomal lysates followed by overrepresentation analysis and interactome studies revealed enrichment of cell adhesion and cell migration proteins in exosomes from stiff ECM cultures compared to that of soft ones. ...Knockdown studies confirmed …
Proteomic analysis of exosomal lysates followed by overrepresentation analysis and interactome studies revealed enrichment of cell ad …
Exosomes in Colorectal Cancer: From Physiology to Clinical Applications.
Titu S, Gata VA, Decea RM, Mocan T, Dina C, Irimie A, Lisencu CI. Titu S, et al. Int J Mol Sci. 2023 Feb 23;24(5):4382. doi: 10.3390/ijms24054382. Int J Mol Sci. 2023. PMID: 36901813 Free PMC article. Review.
Exosomes are nanosized vesicles that have been found to be involved in many diseases. Exosomes can mediate communication between cells in a variety of ways. ...Reported data demonstrate that the serum expression level of certain exosomal miRNA is significantl …
Exosomes are nanosized vesicles that have been found to be involved in many diseases. Exosomes can mediate communication betwe …
Exosomes in subarachnoid hemorrhage: A scoping review.
Bhimani AD, Kalagara R, Chennareddy S, Kellner CP. Bhimani AD, et al. J Clin Neurosci. 2022 Nov;105:58-65. doi: 10.1016/j.jocn.2022.08.025. Epub 2022 Sep 7. J Clin Neurosci. 2022. PMID: 36084567
Of these, two studies analyzed the expression profile of endogenous exosomes after SAH. Four papers identified and characterized miRNA-based exosomal therapies to attenuate early brain injury (EBI) after SAH. One paper discussed the role of protein overexpression in …
Of these, two studies analyzed the expression profile of endogenous exosomes after SAH. Four papers identified and characterized miRN …
MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity.
Zhang S, Chuah SJ, Lai RC, Hui JHP, Lim SK, Toh WS. Zhang S, et al. Biomaterials. 2018 Feb;156:16-27. doi: 10.1016/j.biomaterials.2017.11.028. Epub 2017 Nov 21. Biomaterials. 2018. PMID: 29182933
Here we investigate the cellular processes modulated by MSC exosomes and the mechanism of action underlying the exosome-mediated responses in cartilage repair. ...Using chondrocyte cultures, we could attribute the rapid cellular proliferation and infiltration during …
Here we investigate the cellular processes modulated by MSC exosomes and the mechanism of action underlying the exosome-mediat …
Exosomes carrying immune checkpoints, a promising therapeutic approach in cancer treatment.
Rasihashemi SZ, Sahrai H, Rezazadeh-Gavgani E, Yazdani Y, Khalaji A, Lotfinejad P. Rasihashemi SZ, et al. Med Oncol. 2022 Sep 7;39(12):183. doi: 10.1007/s12032-022-01781-1. Med Oncol. 2022. PMID: 36071295 Review.
Exosomes are being studied as possible cancer vaccines, with numerous uses in tumor immunotherapy. Exosomes can carry chemotherapeutics, siRNA, and monoclonal antibodies. Exosomes produced by macrophages might be used to treat cancer. ...
Exosomes are being studied as possible cancer vaccines, with numerous uses in tumor immunotherapy. Exosomes can carry chemothe …
Trem2 deletion enhances tau dispersion and pathology through microglia exosomes.
Zhu B, Liu Y, Hwang S, Archuleta K, Huang H, Campos A, Murad R, Piña-Crespo J, Xu H, Huang TY. Zhu B, et al. Mol Neurodegener. 2022 Sep 2;17(1):58. doi: 10.1186/s13024-022-00562-8. Mol Neurodegener. 2022. PMID: 36056435 Free PMC article.
Trem2 deletion in microglia enhances intraneuronal dispersion of tau in vitro between neuronal layers cultured in a microfluidic chamber, and the presence of exosome inhibitors can significantly reduce tau in exosomes and extracellular media from tau-loaded microgli …
Trem2 deletion in microglia enhances intraneuronal dispersion of tau in vitro between neuronal layers cultured in a microfluidic chamber, an …
43,558 results
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