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Page 1
Brain exosomes as minuscule information hub for Autism Spectrum Disorder.
Dean DD, Agarwal S, Muthuswamy S, Asim A. Dean DD, et al. Expert Rev Mol Diagn. 2021 Dec;21(12):1323-1331. doi: 10.1080/14737159.2021.2000395. Epub 2021 Nov 25. Expert Rev Mol Diagn. 2021. PMID: 34720032 Review.
INTRODUCTION: Autism spectrum disorder (ASD) is a neurodevelopmental disorder initiating in the first three years of life. ...The studies reviewed herein were identified via systematic search (dated: June 2021) of PubMed using variations related to autism …
INTRODUCTION: Autism spectrum disorder (ASD) is a neurodevelopmental disorder initiating in the first three years of li …
Mesenchymal Stem Cell-Derived Exosomes as New Remedy for the Treatment of Neurocognitive Disorders.
Harrell CR, Volarevic A, Djonov V, Volarevic V. Harrell CR, et al. Int J Mol Sci. 2021 Feb 1;22(3):1433. doi: 10.3390/ijms22031433. Int J Mol Sci. 2021. PMID: 33535376 Free PMC article. Review.
Mesenchymal stem cell (MSC)-derived exosomes (MSC-Exo) are nano-sized extracellular vesicles enriched with MSC-sourced neuroprotective and immunomodulatory microRNAs, neural growth factors, and anti-inflammatory cytokines, which attenuate neuro-inflammation, promote neo-va …
Mesenchymal stem cell (MSC)-derived exosomes (MSC-Exo) are nano-sized extracellular vesicles enriched with MSC-sourced neuroprotectiv …
Mesenchymal Stem Cell-Derived Exosomes for Treatment of Autism Spectrum Disorder.
Liang Y, Duan L, Xu X, Li X, Liu M, Chen H, Lu J, Xia J. Liang Y, et al. ACS Appl Bio Mater. 2020 Sep 21;3(9):6384-6393. doi: 10.1021/acsabm.0c00831. Epub 2020 Aug 31. ACS Appl Bio Mater. 2020. PMID: 35021769
Animal experiments and clinical studies have shown that transplantation of mesenchymal stem cells (MSCs) has a positive effect on the treatment of autism spectrum disorder (ASD). However, the therapeutic efficacy of the MSC transplants was primarily associated with …
Animal experiments and clinical studies have shown that transplantation of mesenchymal stem cells (MSCs) has a positive effect on the treatm …
Stem Cell-Derived Exosomes in Autism Spectrum Disorder.
Alessio N, Brigida AL, Peluso G, Antonucci N, Galderisi U, Siniscalco D. Alessio N, et al. Int J Environ Res Public Health. 2020 Feb 4;17(3):944. doi: 10.3390/ijerph17030944. Int J Environ Res Public Health. 2020. PMID: 32033002 Free PMC article. Review.
Neurodevelopmental lifelong pathologies defined by problems with social interaction, communication capacity and presence of repetitive/stereotyped clusters of behavior and interests are grouped under the definition of autism spectrum disorder (ASD). ASD prevalence i …
Neurodevelopmental lifelong pathologies defined by problems with social interaction, communication capacity and presence of repetitive/stere …
Exosome lncRNA IFNG-AS1 derived from mesenchymal stem cells of human adipose ameliorates neurogenesis and ASD-like behavior in BTBR mice.
Fu Y, Zhang YL, Liu RQ, Xu MM, Xie JL, Zhang XL, Xie GM, Han YT, Zhang XM, Zhang WT, Zhang J, Zhang J. Fu Y, et al. J Nanobiotechnology. 2024 Feb 17;22(1):66. doi: 10.1186/s12951-024-02338-2. J Nanobiotechnology. 2024. PMID: 38368393 Free PMC article.
BACKGROUND: The transplantation of exosomes derived from human adipose-derived mesenchymal stem cells (hADSCs) has emerged as a prospective cellular-free therapeutic intervention for the treatment of neurodevelopmental disorders (NDDs), as well as autism spectrum …
BACKGROUND: The transplantation of exosomes derived from human adipose-derived mesenchymal stem cells (hADSCs) has emerged as a prosp …
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation.
Torre D, Fstkchyan YS, Ho JSY, Cheon Y, Patel RS, Degrace EJ, Mzoughi S, Schwarz M, Mohammed K, Seo JS, Romero-Bueno R, Demircioglu D, Hasson D, Tang W, Mahajani SU, Campisi L, Zheng S, Song WS, Wang YC, Shah H, Francoeur N, Soto J, Salfati Z, Weirauch MT, Warburton P, Beaumont K, Smith ML, Mulder L, Villalta SA, Kessenbrock K, Jang C, Lee D, De Rubeis S, Cobos I, Tam O, Hammell MG, Seldin M, Shi Y, Basu U, Sebastiano V, Byun M, Sebra R, Rosenberg BR, Benner C, Guccione E, Marazzi I. Torre D, et al. Mol Cell. 2023 Dec 7;83(23):4255-4271.e9. doi: 10.1016/j.molcel.2023.10.036. Epub 2023 Nov 22. Mol Cell. 2023. PMID: 37995687 Free PMC article.
Here, we demonstrate that transcription-associated RNA degradation by the nuclear RNA exosome and Integrator is a regulatory mechanism that controls the productive transcription of most genes and many ERVs involved in preimplantation development. ...
Here, we demonstrate that transcription-associated RNA degradation by the nuclear RNA exosome and Integrator is a regulatory mechanis …
Exosomes as drug delivery vehicles and biomarkers for neurological and auditory systems.
Mittal R, Bencie N, Langlie J, Mittal J, Eshraghi AA. Mittal R, et al. J Cell Physiol. 2021 Dec;236(12):8035-8049. doi: 10.1002/jcp.30484. Epub 2021 Jul 5. J Cell Physiol. 2021. PMID: 34224589 Review.
Exosomes are small extracellular membrane particles that play a crucial role in intracellular signaling. Research shows that exosomes have the potential to be used as biomarkers or drug delivery systems in specific organs, such as the neurological system and the inn …
Exosomes are small extracellular membrane particles that play a crucial role in intracellular signaling. Research shows that exoso …
Exosomes: New biomarker and therapeutic candidates in autism spectrum disorder research.
Ünal D, Sarıköse Özgüven A. Ünal D, et al. Acta Neuropsychiatr. 2025 Nov 21;38:e6. doi: 10.1017/neu.2025.10047. Acta Neuropsychiatr. 2025. PMID: 41267515 Free PMC article.
BACKGROUND: There is no recognised cure or specific biomarker for autism spectrum disorder (ASD). Exosomes are small vesicles that carry proteins, lipids and nucleic acids. ...METHODS: In this systematic review, 31 PubMed articles were identified using the ke …
BACKGROUND: There is no recognised cure or specific biomarker for autism spectrum disorder (ASD). Exosomes are small ve …
Detection of disease-associated microRNAs - application for autism spectrum disorders.
Konečná B, Radošinská J, Keményová P, Repiská G. Konečná B, et al. Rev Neurosci. 2020 Oct 25;31(7):757-769. doi: 10.1515/revneuro-2020-0015. Rev Neurosci. 2020. PMID: 32813679 Review.
Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. ...Extracellular vesicles, and their subset of exosomes, are believed to be a tool of cell-to-cell communication, and they are increasingly considered to be carriers of suc …
Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological marker. ...Extracellular vesicles, and their su …
54 results