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Year Number of Results
1891 1
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1947 13
1948 14
1949 2
1950 1
1951 1
1954 1
1955 1
1961 7
1962 1
1963 2
1964 1
1965 13
1966 18
1967 13
1968 10
1969 11
1970 17
1971 9
1972 12
1973 13
1974 20
1975 34
1976 37
1977 41
1978 64
1979 87
1980 68
1981 88
1982 111
1983 127
1984 161
1985 167
1986 185
1987 195
1988 240
1989 264
1990 302
1991 294
1992 338
1993 337
1994 396
1995 454
1996 552
1997 555
1998 561
1999 705
2000 782
2001 929
2002 944
2003 1063
2004 1125
2005 1218
2006 1361
2007 1409
2008 1487
2009 1546
2010 1630
2011 1688
2012 1910
2013 1972
2014 1971
2015 2039
2016 2101
2017 2190
2018 2384
2019 2475
2020 2953
2021 3387
2022 3551
2023 3370
2024 3236
2025 1219

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51,532 results

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Page 1
ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis.
Chen C, Zhang Z, Liu C, Sun P, Liu P, Li X. Chen C, et al. Cell Metab. 2024 Mar 5;36(3):498-510.e11. doi: 10.1016/j.cmet.2023.12.015. Epub 2024 Jan 4. Cell Metab. 2024. PMID: 38181789 Free article.
Elevation of transcription factor TFEB-dependent lysosomal biogenesis and antibacterial innate immunity are observed in inflammatory macrophages with deficiency of ABCG2-mediated itaconate export. Furthermore, deficiency of ABCG2-mediated itaconate export in macroph …
Elevation of transcription factor TFEB-dependent lysosomal biogenesis and antibacterial innate immunity are observed in inflammatory macroph …
Hepcidin-Ferroportin Interaction Controls Systemic Iron Homeostasis.
Nemeth E, Ganz T. Nemeth E, et al. Int J Mol Sci. 2021 Jun 17;22(12):6493. doi: 10.3390/ijms22126493. Int J Mol Sci. 2021. PMID: 34204327 Free PMC article. Review.
In vertebrates, the stability of iron concentration in plasma and extracellular fluid, and the total body iron content are maintained by the interaction of the iron-regulatory peptide hormone hepcidin with its receptor and cellular iron exporter ferroportin (SLC40a1). Ferr …
In vertebrates, the stability of iron concentration in plasma and extracellular fluid, and the total body iron content are maintained by the …
Engineering RNA export for measurement and manipulation of living cells.
Horns F, Martinez JA, Fan C, Haque M, Linton JM, Tobin V, Santat L, Maggiolo AO, Bjorkman PJ, Lois C, Elowitz MB. Horns F, et al. Cell. 2023 Aug 17;186(17):3642-3658.e32. doi: 10.1016/j.cell.2023.06.013. Epub 2023 Jul 11. Cell. 2023. PMID: 37437570 Free PMC article.
We developed genetically encoded cellular RNA exporters, inspired by viruses, that efficiently package and secrete cargo RNA molecules from mammalian cells within protective nanoparticles. Exporting and sequencing RNA barcodes enabled non-destructive monitoring of c …
We developed genetically encoded cellular RNA exporters, inspired by viruses, that efficiently package and secrete cargo RNA molecule …
ATP-Binding Cassette Exporter PDR11-Mediated Terpenoid Secretion in Engineered Yeast.
Xu Y, Han L, Cheng Y, Zhang Y, Wu Y, Liu Y, Li J, Du G, Lv X, Liu L. Xu Y, et al. ACS Synth Biol. 2023 Apr 21;12(4):1146-1153. doi: 10.1021/acssynbio.2c00635. Epub 2023 Apr 4. ACS Synth Biol. 2023. PMID: 37014059
The metabolic burden caused by terpenoid accumulation limits the development of highly efficient microbial cell factories, which can be circumvented using exporter-mediated product secretion. Although our previous study showed that the pleiotropic drug resistance export …
The metabolic burden caused by terpenoid accumulation limits the development of highly efficient microbial cell factories, which can be circ …
Biophysical methods toolbox to study ABC exporter structure and function.
Marcellino T, Srinivasan V. Marcellino T, et al. Biol Chem. 2017 Feb 1;398(2):229-235. doi: 10.1515/hsz-2016-0244. Biol Chem. 2017. PMID: 27727141 Review.
ABC exporters are highly dynamic membrane proteins that span a huge spectrum of different conformations. ...This mini review summarizes some of the biophysical tools that have made a major impact in understanding the function of the ABC exporters....
ABC exporters are highly dynamic membrane proteins that span a huge spectrum of different conformations. ...This mini review summariz …
ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP.
Maltbaek JH, Cambier S, Snyder JM, Stetson DB. Maltbaek JH, et al. Immunity. 2022 Oct 11;55(10):1799-1812.e4. doi: 10.1016/j.immuni.2022.08.006. Epub 2022 Sep 6. Immunity. 2022. PMID: 36070769 Free PMC article.
Here, we identifed ABCC1 as a direct, ATP-dependent cGAMP exporter in mouse and human cells. We show that ABCC1 overexpression enhanced cGAMP export and limited STING signaling and that loss of ABCC1 reduced cGAMP export and potentiated STING signaling. We de …
Here, we identifed ABCC1 as a direct, ATP-dependent cGAMP exporter in mouse and human cells. We show that ABCC1 overexpression enhanc …
The cell cholesterol exporter ABCA1 as a protector from cardiovascular disease and diabetes.
Tang C, Oram JF. Tang C, et al. Biochim Biophys Acta. 2009 Jul;1791(7):563-72. doi: 10.1016/j.bbalip.2009.03.011. Epub 2009 Apr 1. Biochim Biophys Acta. 2009. PMID: 19344785 Review.
ATP-binding cassette transporter A1 (ABCA1) is an integral cell membrane protein that exports cholesterol from cells and suppresses macrophage inflammation. ABCA1 exports cholesterol by a multistep pathway that involves forming cell-surface lipid domains, solubilizi …
ATP-binding cassette transporter A1 (ABCA1) is an integral cell membrane protein that exports cholesterol from cells and suppresses m …
A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics.
Malla S, van der Helm E, Darbani B, Wieschalka S, Förster J, Borodina I, Sommer MOA. Malla S, et al. Front Microbiol. 2022 Apr 14;13:855736. doi: 10.3389/fmicb.2022.855736. eCollection 2022. Front Microbiol. 2022. PMID: 35495724 Free PMC article.
Lack of active export system often limits the industrial bio-based production processes accumulating the intracellular product and hence complexing the purification steps. L-lysine, an essential amino acid, is produced biologically in quantities exceeding two million tons …
Lack of active export system often limits the industrial bio-based production processes accumulating the intracellular product and he …
l-Alanine Exporter AlaE Functions as One of the d-Alanine Exporters in Escherichia coli.
Katsube S, Sakai K, Ando T, Tobe R, Yoneyama H. Katsube S, et al. Int J Mol Sci. 2023 Jun 16;24(12):10242. doi: 10.3390/ijms241210242. Int J Mol Sci. 2023. PMID: 37373388 Free PMC article.
Recently, Escherichia coli has been found to possess one or more energy-dependent d-alanine export systems. To gain insight into these systems, we developed a novel screening system in which cells expressing a putative d-alanine exporter could support the growth of …
Recently, Escherichia coli has been found to possess one or more energy-dependent d-alanine export systems. To gain insight into thes …
Characterization of the Nicotianamine Exporter ENA1 in Rice.
Nozoye T, von Wirén N, Sato Y, Higashiyama T, Nakanishi H, Nishizawa NK. Nozoye T, et al. Front Plant Sci. 2019 Apr 30;10:502. doi: 10.3389/fpls.2019.00502. eCollection 2019. Front Plant Sci. 2019. PMID: 31114596 Free PMC article.
In this study, the physiological role of the efflux transporter EFFLUX TRANSPORTER OF NA (ENA1), which exports NA out of cells, was analyzed in rice. Promoter-GUS analysis showed that ENA1 was mainly expressed in roots, and strongly upregulated under Fe-deficient condition …
In this study, the physiological role of the efflux transporter EFFLUX TRANSPORTER OF NA (ENA1), which exports NA out of cells, was a …
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