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The exposome and health: Where chemistry meets biology.
Vermeulen R, Schymanski EL, Barabási AL, Miller GW. Vermeulen R, et al. Science. 2020 Jan 24;367(6476):392-396. doi: 10.1126/science.aay3164. Science. 2020. PMID: 31974245 Free PMC article. Review.
To safeguard current and future generations from the increasing number of chemicals polluting our environment, a systematic and agnostic approach is needed. The "exposome" concept strives to capture the diversity and range of exposures to synthetic chemicals, dietary const …
To safeguard current and future generations from the increasing number of chemicals polluting our environment, a systematic and agnostic app …
What is new in the exposome?
Vineis P, Robinson O, Chadeau-Hyam M, Dehghan A, Mudway I, Dagnino S. Vineis P, et al. Environ Int. 2020 Oct;143:105887. doi: 10.1016/j.envint.2020.105887. Epub 2020 Jun 30. Environ Int. 2020. PMID: 32619912 Free article. Review.
In this review we provide examples of recent contributions from exposome research, where we believe their application will be of the greatest value for moving forward. ...Finally, exposome research is facilitated by technological developments that complement traditi …
In this review we provide examples of recent contributions from exposome research, where we believe their application will be of the …
Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease.
Celebi Sozener Z, Ozdel Ozturk B, Cerci P, Turk M, Gorgulu Akin B, Akdis M, Altiner S, Ozbey U, Ogulur I, Mitamura Y, Yilmaz I, Nadeau K, Ozdemir C, Mungan D, Akdis CA. Celebi Sozener Z, et al. Allergy. 2022 May;77(5):1418-1449. doi: 10.1111/all.15240. Epub 2022 Feb 16. Allergy. 2022. PMID: 35108405 Free PMC article. Review.
Environmental exposure plays a major role in the development of allergic diseases. The exposome can be classified into internal (e.g., aging, hormones, and metabolic processes), specific external (e.g., chemical pollutants or lifestyle factors), and general external (e.g., …
Environmental exposure plays a major role in the development of allergic diseases. The exposome can be classified into internal (e.g. …
The Exposome and Asthma.
Subramanian A, Khatri SB. Subramanian A, et al. Clin Chest Med. 2019 Mar;40(1):107-123. doi: 10.1016/j.ccm.2018.10.017. Epub 2018 Dec 20. Clin Chest Med. 2019. PMID: 30691706 Review.
This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, development, and stages of life. ...
This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, d …
The contribution of the exposome to the burden of cardiovascular disease.
Münzel T, Sørensen M, Hahad O, Nieuwenhuijsen M, Daiber A. Münzel T, et al. Nat Rev Cardiol. 2023 Oct;20(10):651-669. doi: 10.1038/s41569-023-00873-3. Epub 2023 May 10. Nat Rev Cardiol. 2023. PMID: 37165157 Review.
We discuss selected exposome studies and highlight the relevance of the exposome concept for future health research as well as preventive medicine. We also discuss the challenges and limitations of exposome studies....
We discuss selected exposome studies and highlight the relevance of the exposome concept for future health research as well as …
Environmental risk factors of type 2 diabetes-an exposome approach.
Beulens JWJ, Pinho MGM, Abreu TC, den Braver NR, Lam TM, Huss A, Vlaanderen J, Sonnenschein T, Siddiqui NZ, Yuan Z, Kerckhoffs J, Zhernakova A, Brandao Gois MF, Vermeulen RCH. Beulens JWJ, et al. Diabetologia. 2022 Feb;65(2):263-274. doi: 10.1007/s00125-021-05618-w. Epub 2021 Nov 18. Diabetologia. 2022. PMID: 34792619 Review.
The external exposome comprises aspects of the built environment, the social environment, the physico-chemical environment and the lifestyle/food environment. ...In this review, we describe the evidence for environmental risk factors of type 2 diabetes, focusing on both th …
The external exposome comprises aspects of the built environment, the social environment, the physico-chemical environment and the li …
The exposome in rheumatoid arthritis.
Biton J, Saidenberg-Kermanac'h N, Decker P, Boissier MC, Semerano L, Sigaux J. Biton J, et al. Joint Bone Spine. 2022 Nov;89(6):105455. doi: 10.1016/j.jbspin.2022.105455. Epub 2022 Aug 12. Joint Bone Spine. 2022. PMID: 35964886 Review.
The exposome integrates the variety and accumulation of exposures (external and internal) to which an individual is submitted to from conception to death. ...The combination of these changes and the external signals that cause them constitute an individual's exposome …
The exposome integrates the variety and accumulation of exposures (external and internal) to which an individual is submitted to from …
Exposome: Epigenetics and autoimmune diseases.
Danieli MG, Casciaro M, Paladini A, Bartolucci M, Sordoni M, Shoenfeld Y, Gangemi S. Danieli MG, et al. Autoimmun Rev. 2024 Jun;23(6):103584. doi: 10.1016/j.autrev.2024.103584. Epub 2024 Aug 2. Autoimmun Rev. 2024. PMID: 39097180 Free article. Review.
Even though genetic predisposition plays a role, it cannot fully explain the onset of these diseases, highlighting the significant impact of non-heritable influences such as environment, hormones and infections. The exposome represents all those factors, ranging from chemi …
Even though genetic predisposition plays a role, it cannot fully explain the onset of these diseases, highlighting the significant impact of …
The exposome and liver disease - how environmental factors affect liver health.
Barouki R, Samson M, Blanc EB, Colombo M, Zucman-Rossi J, Lazaridis KN, Miller GW, Coumoul X. Barouki R, et al. J Hepatol. 2023 Aug;79(2):492-505. doi: 10.1016/j.jhep.2023.02.034. Epub 2023 Mar 6. J Hepatol. 2023. PMID: 36889360 Free PMC article. Review.
Since the initial development of the exposome concept, much effort has been devoted to the characterisation of the exposome through analytical, epidemiological, and toxicological/mechanistic studies. There is now an urgent need to link the exposome to human d …
Since the initial development of the exposome concept, much effort has been devoted to the characterisation of the exposome th …
The exposome as the science of social-to-biological transitions.
Vineis P, Barouki R. Vineis P, et al. Environ Int. 2022 Jul;165:107312. doi: 10.1016/j.envint.2022.107312. Epub 2022 May 21. Environ Int. 2022. PMID: 35635963 Free article. Review.
Here we propose a scheme for the practice of epidemiology and toxicology that incorporates new recent advancements in both disciplines, under the general umbrella of the "exposome". The exposome approach to disease encompasses a lifecourse perspective from conceptio …
Here we propose a scheme for the practice of epidemiology and toxicology that incorporates new recent advancements in both disciplines, unde …
2,784 results

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