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3,558 results

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Page 1
The exposome and health: Where chemistry meets biology.
Vermeulen R, Schymanski EL, Barabási AL, Miller GW. Vermeulen R, et al. Science. 2020 Jan 24;367(6476):392-396. doi: 10.1126/science.aay3164. Science. 2020. PMID: 31974245 Free PMC article. Review.
To safeguard current and future generations from the increasing number of chemicals polluting our environment, a systematic and agnostic approach is needed. The "exposome" concept strives to capture the diversity and range of exposures to synthetic chemicals, dietary const …
To safeguard current and future generations from the increasing number of chemicals polluting our environment, a systematic and agnostic app …
The contribution of the exposome to the burden of cardiovascular disease.
Münzel T, Sørensen M, Hahad O, Nieuwenhuijsen M, Daiber A. Münzel T, et al. Nat Rev Cardiol. 2023 Oct;20(10):651-669. doi: 10.1038/s41569-023-00873-3. Epub 2023 May 10. Nat Rev Cardiol. 2023. PMID: 37165157 Review.
We discuss selected exposome studies and highlight the relevance of the exposome concept for future health research as well as preventive medicine. We also discuss the challenges and limitations of exposome studies....
We discuss selected exposome studies and highlight the relevance of the exposome concept for future health research as well as …
What is new in the exposome?
Vineis P, Robinson O, Chadeau-Hyam M, Dehghan A, Mudway I, Dagnino S. Vineis P, et al. Environ Int. 2020 Oct;143:105887. doi: 10.1016/j.envint.2020.105887. Epub 2020 Jun 30. Environ Int. 2020. PMID: 32619912 Free article. Review.
In this review we provide examples of recent contributions from exposome research, where we believe their application will be of the greatest value for moving forward. ...Finally, exposome research is facilitated by technological developments that complement traditi …
In this review we provide examples of recent contributions from exposome research, where we believe their application will be of the …
Exposome: Epigenetics and autoimmune diseases.
Danieli MG, Casciaro M, Paladini A, Bartolucci M, Sordoni M, Shoenfeld Y, Gangemi S. Danieli MG, et al. Autoimmun Rev. 2024 Jun;23(6):103584. doi: 10.1016/j.autrev.2024.103584. Epub 2024 Aug 2. Autoimmun Rev. 2024. PMID: 39097180 Free article. Review.
Even though genetic predisposition plays a role, it cannot fully explain the onset of these diseases, highlighting the significant impact of non-heritable influences such as environment, hormones and infections. The exposome represents all those factors, ranging from chemi …
Even though genetic predisposition plays a role, it cannot fully explain the onset of these diseases, highlighting the significant impact of …
The exposome and liver disease - how environmental factors affect liver health.
Barouki R, Samson M, Blanc EB, Colombo M, Zucman-Rossi J, Lazaridis KN, Miller GW, Coumoul X. Barouki R, et al. J Hepatol. 2023 Aug;79(2):492-505. doi: 10.1016/j.jhep.2023.02.034. Epub 2023 Mar 6. J Hepatol. 2023. PMID: 36889360 Free PMC article. Review.
Since the initial development of the exposome concept, much effort has been devoted to the characterisation of the exposome through analytical, epidemiological, and toxicological/mechanistic studies. There is now an urgent need to link the exposome to human d …
Since the initial development of the exposome concept, much effort has been devoted to the characterisation of the exposome th …
The Exposome and Asthma.
Subramanian A, Khatri SB. Subramanian A, et al. Clin Chest Med. 2019 Mar;40(1):107-123. doi: 10.1016/j.ccm.2018.10.017. Epub 2018 Dec 20. Clin Chest Med. 2019. PMID: 30691706 Review.
This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, development, and stages of life. ...
This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, d …
Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.
Pandics T, Major D, Fazekas-Pongor V, Szarvas Z, Peterfi A, Mukli P, Gulej R, Ungvari A, Fekete M, Tompa A, Tarantini S, Yabluchanskiy A, Conley S, Csiszar A, Tabak AG, Benyo Z, Adany R, Ungvari Z. Pandics T, et al. Geroscience. 2023 Dec;45(6):3381-3408. doi: 10.1007/s11357-023-00913-3. Epub 2023 Sep 9. Geroscience. 2023. PMID: 37688657 Free PMC article. Review.
This comprehensive review paper delves into the impact of the exposome, which encompasses the totality of environmental exposures, on unhealthy aging. ...
This comprehensive review paper delves into the impact of the exposome, which encompasses the totality of environmental exposures, on …
Environmental risk factors of type 2 diabetes-an exposome approach.
Beulens JWJ, Pinho MGM, Abreu TC, den Braver NR, Lam TM, Huss A, Vlaanderen J, Sonnenschein T, Siddiqui NZ, Yuan Z, Kerckhoffs J, Zhernakova A, Brandao Gois MF, Vermeulen RCH. Beulens JWJ, et al. Diabetologia. 2022 Feb;65(2):263-274. doi: 10.1007/s00125-021-05618-w. Epub 2021 Nov 18. Diabetologia. 2022. PMID: 34792619 Review.
The external exposome comprises aspects of the built environment, the social environment, the physico-chemical environment and the lifestyle/food environment. ...In this review, we describe the evidence for environmental risk factors of type 2 diabetes, focusing on both th …
The external exposome comprises aspects of the built environment, the social environment, the physico-chemical environment and the li …
[Skin aging exposome].
Krutmann J, Grether-Beck S, Makrantonaki E, Schikowski T. Krutmann J, et al. Dermatologie (Heidelb). 2023 Sep;74(9):657-662. doi: 10.1007/s00105-023-05210-w. Epub 2023 Aug 18. Dermatologie (Heidelb). 2023. PMID: 37594514 Review. German.
In order to describe and understand this complex process exactly, we applied the concept of the "exposome" to the environmentally induced skin aging process. In this review, we summarize current knowledge on the skin aging exposome. ...
In order to describe and understand this complex process exactly, we applied the concept of the "exposome" to the environmentally ind …
Exposome in ischaemic heart disease: beyond traditional risk factors.
Montone RA, Camilli M, Calvieri C, Magnani G, Bonanni A, Bhatt DL, Rajagopalan S, Crea F, Niccoli G. Montone RA, et al. Eur Heart J. 2024 Feb 7;45(6):419-438. doi: 10.1093/eurheartj/ehae001. Eur Heart J. 2024. PMID: 38238478 Free PMC article. Review.
For this reason, a new paradigm called the 'exposome' has recently been introduced by epidemiologists in order to define the totality of exposure to these new risk factors. ...
For this reason, a new paradigm called the 'exposome' has recently been introduced by epidemiologists in order to define the totality …
3,558 results