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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
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2,078 results

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Page 1
Personalized molecular signatures of insulin resistance and type 2 diabetes.
Kjærgaard J, Stocks B, Henderson J, Freemantle JB, Rizo-Roca D, Puglia M, Madrazo Montoya M, Andersson D, Bäckdahl J, Eriksson-Hogling D, Stidsen JV, Wierer M, Rasmussen S, Sakamoto K, Højlund K, Rydén M, Zierath JR, Krook A, Deshmukh AS. Kjærgaard J, et al. Cell. 2025 Jul 24;188(15):4106-4122.e16. doi: 10.1016/j.cell.2025.05.005. Epub 2025 May 27. Cell. 2025. PMID: 40436015 Free article.
Insulin resistance is a hallmark of type 2 diabetes, which is a highly heterogeneous disease with diverse pathology. ...Utilizing cutting-edge proteomics technology, we mapped the proteome and phosphoproteome of skeletal muscle from >120 men and wom …
Insulin resistance is a hallmark of type 2 diabetes, which is a highly heterogeneous disease with diverse pathol …
Type 2 Diabetes and Cancer: An Umbrella Review of Observational and Mendelian Randomization Studies.
Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK. Pearson-Stuttard J, et al. Cancer Epidemiol Biomarkers Prev. 2021 Jun;30(6):1218-1228. doi: 10.1158/1055-9965.EPI-20-1245. Epub 2021 Mar 18. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 33737302 Free PMC article.
BACKGROUND: Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of developing several common cancers, but it is unclear whether this association is causal. ...Positive associations were found between genetically predicted …
BACKGROUND: Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of developing several com …
Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study.
Chen J, Yuan S, Fu T, Ruan X, Qiao J, Wang X, Li X, Gill D, Burgess S, Giovannucci EL, Larsson SC. Chen J, et al. Diabetes Care. 2023 Apr 1;46(4):828-835. doi: 10.2337/dc22-1385. Diabetes Care. 2023. PMID: 36800530 Free PMC article.
OBJECTIVE: We conducted a Mendelian randomization (MR) study to examine the associations of type 2 diabetes and glycemic traits with gastrointestinal diseases (GDs). RESEARCH DESIGN AND METHODS: Uncorrelated genetic variants associated with type 2 …
OBJECTIVE: We conducted a Mendelian randomization (MR) study to examine the associations of type 2 diabetes and glycemi …
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Matthews DR, et al. Diabetologia. 1985 Jul;28(7):412-9. doi: 10.1007/BF00280883. Diabetologia. 1985. PMID: 3899825
The steady-state basal plasma glucose and insulin concentrations are determined by their interaction in a feedback loop. A computer-solved model has been used to predict the homeostatic concentrations which arise from varying degrees beta-cell deficiency and insu …
The steady-state basal plasma glucose and insulin concentrations are determined by their interaction in a feedback loop. A computer-s …
Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes.
Huang W, Xie C, Wewer Albrechtsen NJ, Sang M, Sun Z, Jones KL, Horowitz M, Rayner CK, Wu T. Huang W, et al. Peptides. 2023 Nov;169:171092. doi: 10.1016/j.peptides.2023.171092. Epub 2023 Sep 4. Peptides. 2023. PMID: 37673303 Free article.
Serum liver enzyme levels, including alanine transaminase (ALT), aspartate transaminase (AST) and gamma-glutamyl transferase (GGT), are reportedly predictive of the risk of type 2 diabetes (T2D). However, the link between the liver enzyme profile and m …
Serum liver enzyme levels, including alanine transaminase (ALT), aspartate transaminase (AST) and gamma-glutamyl transferase (GGT), are repo …
Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study.
Jones AG, Shields BM, Oram RA, Dabelea DM, Hagopian WA, Sharp SA, Lustigova E, Shah AS, Knupp J, Mottl AK, D'Agostino RB Jr, Williams A, Marcovina SM, Pihoker C, Divers J, Redondo MJ. Jones AG, et al. Diabetes Care. 2024 Dec 1;47(12):2110-2119. doi: 10.2337/dc23-1815. Diabetes Care. 2024. PMID: 38252849 Free PMC article.
OBJECTIVE: With high prevalence of obesity and overlapping features between diabetes subtypes, accurately classifying youth-onset diabetes can be challenging. We aimed to develop prediction models that, using characteristics available at diabetes diagnosis, can identify yo …
OBJECTIVE: With high prevalence of obesity and overlapping features between diabetes subtypes, accurately classifying youth-onset diabetes c …
Evaluating the Significance of Fasting C-peptide in Conjunction with the Insulin Resistance Index for Assessing Hepatic Fibrosis in Patients with Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease.
Zhou H, Han L, Wang Y, Zhao Y, Fang C, Zhang X, Li H, Zheng R. Zhou H, et al. Altern Ther Health Med. 2024 Nov;30(11):319-323. Altern Ther Health Med. 2024. PMID: 38430160 Free article.
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) has reached pandemic proportions globally, particularly affecting individuals with type 2 diabetes mellitus (T2DM). OBJECTIVE: Our study aims to elucidate the diagnostic value of fasting C-pe …
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) has reached pandemic proportions globally, particularly affecting individuals with …
Insulin Resistance Is Better Estimated by Using Fasting Glucose, Lipid Profile, and Body Fat Percent Than by HOMA-IR in Japanese Patients with Type 2 Diabetes and Impaired Glucose Tolerance: An Exploratory Study.
Nakamura Y, Otaki S, Tanaka Y, Adachi A, Wada N, Tajiri Y. Nakamura Y, et al. Metab Syndr Relat Disord. 2024 Apr;22(3):199-206. doi: 10.1089/met.2023.0181. Epub 2024 Jan 8. Metab Syndr Relat Disord. 2024. PMID: 38190491
Patients and Methods: Fifty-two admitted patients with type 2 diabetes or impaired glucose tolerance were enrolled, and steady state plasma glucose (SSPG) method and cookie meal tolerance test were performed together with fasting blood sampling and ant …
Patients and Methods: Fifty-two admitted patients with type 2 diabetes or impaired glucose tolerance were enrolled, and …
Prediction of insulin resistance in type 2 diabetes mellitus using routinely available clinical parameters.
Magri CJ, Fava S, Galea J. Magri CJ, et al. Diabetes Metab Syndr. 2016 Apr-Jun;10(2 Suppl 1):S96-S101. doi: 10.1016/j.dsx.2016.03.002. Epub 2016 Mar 28. Diabetes Metab Syndr. 2016. PMID: 27131406
AIMS: To determine if insulin resistance (IR), an important predictor of cardiovascular risk in the general population and in type 2 diabetes mellitus, can be assessed using simple parameters which are readily available in clinical practice. ... …
AIMS: To determine if insulin resistance (IR), an important predictor of cardiovascular risk in the general population and in type …
Low fasting glucose-to-estimated average glucose ratio was associated with superior response to insulin degludec/aspart compared with basal insulin in patients with type 2 diabetes.
Jang HN, Yang YS, Oh TJ, Koo BK, Lee SO, Park KS, Jang HC, Jung HS. Jang HN, et al. J Diabetes Investig. 2022 Jan;13(1):85-93. doi: 10.1111/jdi.13634. Epub 2021 Aug 24. J Diabetes Investig. 2022. PMID: 34291584 Free PMC article. Clinical Trial.
AIMS/INTRODUCTION: The benefits of once-daily insulin degludec/aspart (IDegAsp) compared with basal insulin in type 2 diabetes patients have not been established. ...CONCLUSIONS: We observed that IDegAsp was more effective than basal insulin …
AIMS/INTRODUCTION: The benefits of once-daily insulin degludec/aspart (IDegAsp) compared with basal insulin in type …
2,078 results