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Year Number of Results
2001 1
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313 results

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Page 1
Association of a polygenic risk score with low trauma fractures in people with HIV - The swiss HIV cohort study.
Strickler C, Thorball CW, Schoepf IC, Schwenke J, Hasse B, Ryom L, Thurnheer MC, Fux C, Kahlert CR, Bernasconi E, Calmy A, Lamy O, Günthard HF, Ledergerber B, Fellay J, Tarr PE; Swiss HIV Cohort Study. Strickler C, et al. Among authors: fellay j. PLoS One. 2026 Feb 11;21(2):e0342748. doi: 10.1371/journal.pone.0342748. eCollection 2026. PLoS One. 2026. PMID: 41671232 Free PMC article.
We recently showed that the bone mineral density-associated gSOS-PRS is independently associated with a > 4-fold increased risk of osteoporosis in the Swiss HIV Cohort Study (SHCS). Here we investigate whether this PRS is also associated with low trauma fractures (LTF) …
We recently showed that the bone mineral density-associated gSOS-PRS is independently associated with a > 4-fold increased risk of osteop …
Multi-ancestry GWAS identifies variants in a zinc finger gene cluster as novel regulators of HIV control.
Awada A, Tough RH, Fellay J, McLaren PJ. Awada A, et al. Among authors: fellay j. J Infect Dis. 2026 Feb 5:jiag072. doi: 10.1093/infdis/jiag072. Online ahead of print. J Infect Dis. 2026. PMID: 41640362
BACKGROUND: HIV-1 remains a global health challenge, emphasizing the need to identify new host factors that influence pathogenesis to serve as drug targets. Identifying genetic determinants of HIV-1 control across diverse populations remains a top priority. METHODS: …
BACKGROUND: HIV-1 remains a global health challenge, emphasizing the need to identify new host factors that influence pathogenesis to …
Genetic determinants of HIV-1 elite control.
Ryan B, Fellay J, Thorball CW. Ryan B, et al. Among authors: fellay j. Curr Opin HIV AIDS. 2026 Jan 29. doi: 10.1097/COH.0000000000001019. Online ahead of print. Curr Opin HIV AIDS. 2026. PMID: 41607217
PURPOSE OF REVIEW: Elite controllers, rare individuals who maintain undetectable HIV-1 viremia without antiretroviral therapy, represent a human model of a functional cure. Understanding the host genetic factors that enable this spontaneous viral control is a key goal of …
PURPOSE OF REVIEW: Elite controllers, rare individuals who maintain undetectable HIV-1 viremia without antiretroviral therapy, repres …
Circulating HBV RNA and hepatitis B core-related antigen as determinants of HBsAg loss in persons with HIV in Europe.
Begré L, Boyd A, Plissonnier ML, Testoni B, Béguelin C, Suter-Riniker F, Scholtès C, Rockstroh JK, Lacombe K, Peters L, Heil M, Levrero M, Rauch A, Zoulim F, Wandeler G; Swiss HIV Cohort Study, EuroSIDA and French HIV/HBV and Biliver cohorts; Members of the EuroSIDA Study Group; Members of the French HIV/HBV and Biliver cohorts. Begré L, et al. JHEP Rep. 2025 Nov 7;8(2):101671. doi: 10.1016/j.jhepr.2025.101671. eCollection 2026 Feb. JHEP Rep. 2025. PMID: 41551412 Free PMC article.
BACKGROUND & AIMS: HBsAg loss improves clinical outcomes in persons with HIV and HBV coinfection. We aimed to evaluate if hepatitis B core-related antigen and circulating HBV RNA levels were associated with HBsAg loss in Euro-B, a multi-cohort collaboration including d …
BACKGROUND & AIMS: HBsAg loss improves clinical outcomes in persons with HIV and HBV coinfection. We aimed to evaluate if hepatit …
Association of leukocyte count with death in people with HIV: A longitudinal study over 24 years.
Klein Z, Meyer SC, Schoepf IC, Weber M, Thorball CW, Ryom L, Kootstra NA, Reiss P, Braun DL, Thurnheer MC, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Marinosci A, Fellay J, Kouyos RD, Günthard HF, Ledergerber B, Tarr PE; and the Swiss HIV Cohort Study. Klein Z, et al. Among authors: fellay j. PLoS One. 2026 Jan 8;21(1):e0340678. doi: 10.1371/journal.pone.0340678. eCollection 2026. PLoS One. 2026. PMID: 41505443 Free PMC article.
Limited information is available in people with HIV. METHODS: We analyzed blood leukocytes in 1850 participants of the Swiss HIV Cohort Study who died (2000-2023) and 1850 matched controls (median age at death 52 years, 77% male, 77% with suppressed HIV RNA o …
Limited information is available in people with HIV. METHODS: We analyzed blood leukocytes in 1850 participants of the Swiss HIV …
Changes in Body Mass Index in Children and Adolescents Living With Human Immunodeficiency Virus in Europe and Thailand Starting Dolutegravir.
Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC) Study Group. Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC) Study Group. Open Forum Infect Dis. 2025 Oct 11;12(12):ofaf640. doi: 10.1093/ofid/ofaf640. eCollection 2025 Dec. Open Forum Infect Dis. 2025. PMID: 41426260 Free PMC article.
We assessed (1) zBMI change 48 weeks before versus after DTG start; (2) zBMI change up to 96 weeks on DTG and associated factors; and (3) zBMI changes over 96 weeks in CALHIV aged 6-17 years at start of DTG versus protease inhibitor (PI)-based regimens using propensity score weig …
We assessed (1) zBMI change 48 weeks before versus after DTG start; (2) zBMI change up to 96 weeks on DTG and associated factors; and (3) zB …
The genetic architecture of HIV-1 virulence.
Blanquart F, Wymant C, Hall M, Power R, Golubchik T, Gall A, de Cesare M, Macintyre-Cockett G, Bakker M, Bezemer D, Gabrielaite M, Ong SH, Kendall M, Sauter R, Bannert N, Fellay J, Grabowski MK, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Laeyendecker O, Marvig RL, Meixenberger K, Meyer L, van Sighem A, Bonsall D, van der Valk M, Berkhout B, Kellam P, Cornelissen M, Reiss P, Fraser C. Blanquart F, et al. Among authors: fellay j. Virus Evol. 2025 Dec 5;11(1):veaf057. doi: 10.1093/ve/veaf057. eCollection 2025. Virus Evol. 2025. PMID: 41368623 Free PMC article.
The virulence of Human Immunodeficiency Virus-1 (HIV-1) is partly determined by viral genetic variation. Finding individual genetic variants affecting virulence is important for our understanding of HIV pathogenesis and evolution of virulence; however, very few have …
The virulence of Human Immunodeficiency Virus-1 (HIV-1) is partly determined by viral genetic variation. Finding individual genetic v …
Factors associated with uptake of gynaecological care and cervical cancer screening among women in the Swiss HIV Cohort Study.
Waldecker M, Taghavi K, Pasin C, Tarr PE, Hachfeld A, Munting A, Abela IA, Weisser M, Schlatter B, Nawej O, Bernasconi E, Rohner E, Aebi-Popp K; Swiss HIV Cohort Study (SHCS). Waldecker M, et al. HIV Med. 2025 Dec;26(12):1963-1972. doi: 10.1111/hiv.70137. Epub 2025 Nov 11. HIV Med. 2025. PMID: 41216952 Free PMC article.
OBJECTIVES: We assessed factors associated with attendance at gynaecological visits and cervical cancer screening, and estimated the incidence of cervical dysplasia and cancer among women with HIV (WWH) in Switzerland over two decades. METHODS: We used self-reported gynaec …
OBJECTIVES: We assessed factors associated with attendance at gynaecological visits and cervical cancer screening, and estimated the inciden …
Untargeted Metabolite Profile Associations with Body Mass Index, Waist-Hip Ratio, and Antiretroviral Therapy in >1300 People with HIV: the Swiss HIV Cohort Study.
Labarile M, Schoepf IC, Pasin C, Oumelloul MA, Thorball CW, Riebensahm C, Surial B, Wandeler G, Braun DL, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Calmy A, Nemeth J, Bally L, Reiss P, Telenti A, Ledergerber B, Günthard HF, Fellay J, Zamboni N, Kouyos RD, Tarr PE; Swiss HIV Cohort Study. Labarile M, et al. Among authors: fellay j. J Infect Dis. 2025 Aug 27:jiaf438. doi: 10.1093/infdis/jiaf438. Online ahead of print. J Infect Dis. 2025. PMID: 40858302
BACKGROUND: Obesity is a major concern in people with HIV (PWH). How obesity and antiretroviral therapy (ART) are associated with specific metabolite profiles in PWH is not well described. METHODS: We included Swiss HIV Cohort Study participants aged 45 years. We an …
BACKGROUND: Obesity is a major concern in people with HIV (PWH). How obesity and antiretroviral therapy (ART) are associated with spe …
HIV-phyloTSI: subtype-independent estimation of time since HIV-1 infection for cross-sectional measures of population incidence using deep sequence data.
Golubchik T, Abeler-Dörner L, Hall M, Wymant C, Bonsall D, Macintyre-Cockett G, Thomson L, Baeten JM, Celum CL, Galiwango RM, Kosloff B, Limbada M, Mujugira A, Mugo NR, Gall A, Blanquart F, Bakker M, Bezemer D, Ong SH, Albert J, Bannert N, Fellay J, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Meyer L, Porter K, van Sighem A, van der Valk M, Berkhout B, Kellam P, Cornelissen M, Reiss P, Ayles H, Burns DN, Fidler S, Grabowski MK, Hayes R, Herbeck JT, Kagaayi J, Kaleebu P, Lingappa JR, Ssemwanga D, Eshleman SH, Cohen MS, Ratmann O, Laeyendecker O, Fraser C; HPTN 071 (PopART) Phylogenetics protocol team, the BEEHIVE consortium and the PANGEA consortium. Golubchik T, et al. Among authors: fellay j. BMC Bioinformatics. 2025 Aug 14;26(1):212. doi: 10.1186/s12859-025-06189-y. BMC Bioinformatics. 2025. PMID: 40813968 Free PMC article.
BACKGROUND: Estimating the time since HIV infection (TSI) at population level is essential for tracking changes in the global HIV epidemic. ...It performs equally well for all major HIV subtypes based on data from African and European cohorts. CONCLUSIONS: We …
BACKGROUND: Estimating the time since HIV infection (TSI) at population level is essential for tracking changes in the global HIV …
313 results