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249 results

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Page 1
Association of a polygenic risk score with low trauma fractures in people with HIV - The swiss HIV cohort study.
Strickler C, Thorball CW, Schoepf IC, Schwenke J, Hasse B, Ryom L, Thurnheer MC, Fux C, Kahlert CR, Bernasconi E, Calmy A, Lamy O, Günthard HF, Ledergerber B, Fellay J, Tarr PE; Swiss HIV Cohort Study. Strickler C, et al. Among authors: fellay j. PLoS One. 2026 Feb 11;21(2):e0342748. doi: 10.1371/journal.pone.0342748. eCollection 2026. PLoS One. 2026. PMID: 41671232 Free PMC article.
We recently showed that the bone mineral density-associated gSOS-PRS is independently associated with a > 4-fold increased risk of osteoporosis in the Swiss HIV Cohort Study (SHCS). Here we investigate whether this PRS is also associated with low trauma fractures …
We recently showed that the bone mineral density-associated gSOS-PRS is independently associated with a > 4-fold increased risk of osteop …
Circulating HBV RNA and hepatitis B core-related antigen as determinants of HBsAg loss in persons with HIV in Europe.
Begré L, Boyd A, Plissonnier ML, Testoni B, Béguelin C, Suter-Riniker F, Scholtès C, Rockstroh JK, Lacombe K, Peters L, Heil M, Levrero M, Rauch A, Zoulim F, Wandeler G; Swiss HIV Cohort Study, EuroSIDA and French HIV/HBV and Biliver cohorts; Members of the EuroSIDA Study Group; Members of the French HIV/HBV and Biliver cohorts. Begré L, et al. JHEP Rep. 2025 Nov 7;8(2):101671. doi: 10.1016/j.jhepr.2025.101671. eCollection 2026 Feb. JHEP Rep. 2025. PMID: 41551412 Free PMC article.
BACKGROUND & AIMS: HBsAg loss improves clinical outcomes in persons with HIV and HBV coinfection. We aimed to evaluate if hepatitis B core-related antigen and circulating HBV RNA levels were associated with HBsAg loss in Euro-B, a multi-cohort collaboration incl …
BACKGROUND & AIMS: HBsAg loss improves clinical outcomes in persons with HIV and HBV coinfection. We aimed to evaluate if hepatit …
Association of leukocyte count with death in people with HIV: A longitudinal study over 24 years.
Klein Z, Meyer SC, Schoepf IC, Weber M, Thorball CW, Ryom L, Kootstra NA, Reiss P, Braun DL, Thurnheer MC, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Marinosci A, Fellay J, Kouyos RD, Günthard HF, Ledergerber B, Tarr PE; and the Swiss HIV Cohort Study. Klein Z, et al. Among authors: fellay j. PLoS One. 2026 Jan 8;21(1):e0340678. doi: 10.1371/journal.pone.0340678. eCollection 2026. PLoS One. 2026. PMID: 41505443 Free PMC article.
Limited information is available in people with HIV. METHODS: We analyzed blood leukocytes in 1850 participants of the Swiss HIV Cohort Study who died (2000-2023) and 1850 matched controls (median age at death 52 years, 77% male, 77% with suppressed HIV …
Limited information is available in people with HIV. METHODS: We analyzed blood leukocytes in 1850 participants of the Swiss HIV …
Changes in Body Mass Index in Children and Adolescents Living With Human Immunodeficiency Virus in Europe and Thailand Starting Dolutegravir.
Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC) Study Group. Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC) Study Group. Open Forum Infect Dis. 2025 Oct 11;12(12):ofaf640. doi: 10.1093/ofid/ofaf640. eCollection 2025 Dec. Open Forum Infect Dis. 2025. PMID: 41426260 Free PMC article.
METHODS: CALHIV aged 2-17 years at DTG start from 15 observational cohorts across Europe and Thailand were included. Mixed models described changes in body-mass-index-for-age z-score (zBMI). We assessed (1) zBMI change 48 weeks before versus after DTG start; (2) zBMI chang …
METHODS: CALHIV aged 2-17 years at DTG start from 15 observational cohorts across Europe and Thailand were included. Mixed models des …
Factors associated with uptake of gynaecological care and cervical cancer screening among women in the Swiss HIV Cohort Study.
Waldecker M, Taghavi K, Pasin C, Tarr PE, Hachfeld A, Munting A, Abela IA, Weisser M, Schlatter B, Nawej O, Bernasconi E, Rohner E, Aebi-Popp K; Swiss HIV Cohort Study (SHCS). Waldecker M, et al. HIV Med. 2025 Dec;26(12):1963-1972. doi: 10.1111/hiv.70137. Epub 2025 Nov 11. HIV Med. 2025. PMID: 41216952 Free PMC article.
OBJECTIVES: We assessed factors associated with attendance at gynaecological visits and cervical cancer screening, and estimated the incidence of cervical dysplasia and cancer among women with HIV (WWH) in Switzerland over two decades. METHODS: We used self-reported gynaec …
OBJECTIVES: We assessed factors associated with attendance at gynaecological visits and cervical cancer screening, and estimated the inciden …
Untargeted Metabolite Profile Associations with Body Mass Index, Waist-Hip Ratio, and Antiretroviral Therapy in >1300 People with HIV: the Swiss HIV Cohort Study.
Labarile M, Schoepf IC, Pasin C, Oumelloul MA, Thorball CW, Riebensahm C, Surial B, Wandeler G, Braun DL, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Calmy A, Nemeth J, Bally L, Reiss P, Telenti A, Ledergerber B, Günthard HF, Fellay J, Zamboni N, Kouyos RD, Tarr PE; Swiss HIV Cohort Study. Labarile M, et al. Among authors: fellay j. J Infect Dis. 2025 Aug 27:jiaf438. doi: 10.1093/infdis/jiaf438. Online ahead of print. J Infect Dis. 2025. PMID: 40858302
BACKGROUND: Obesity is a major concern in people with HIV (PWH). How obesity and antiretroviral therapy (ART) are associated with specific metabolite profiles in PWH is not well described. METHODS: We included Swiss HIV Cohort Study participants aged 45 years …
BACKGROUND: Obesity is a major concern in people with HIV (PWH). How obesity and antiretroviral therapy (ART) are associated with spe …
HIV-phyloTSI: subtype-independent estimation of time since HIV-1 infection for cross-sectional measures of population incidence using deep sequence data.
Golubchik T, Abeler-Dörner L, Hall M, Wymant C, Bonsall D, Macintyre-Cockett G, Thomson L, Baeten JM, Celum CL, Galiwango RM, Kosloff B, Limbada M, Mujugira A, Mugo NR, Gall A, Blanquart F, Bakker M, Bezemer D, Ong SH, Albert J, Bannert N, Fellay J, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Meyer L, Porter K, van Sighem A, van der Valk M, Berkhout B, Kellam P, Cornelissen M, Reiss P, Ayles H, Burns DN, Fidler S, Grabowski MK, Hayes R, Herbeck JT, Kagaayi J, Kaleebu P, Lingappa JR, Ssemwanga D, Eshleman SH, Cohen MS, Ratmann O, Laeyendecker O, Fraser C; HPTN 071 (PopART) Phylogenetics protocol team, the BEEHIVE consortium and the PANGEA consortium. Golubchik T, et al. Among authors: fellay j. BMC Bioinformatics. 2025 Aug 14;26(1):212. doi: 10.1186/s12859-025-06189-y. BMC Bioinformatics. 2025. PMID: 40813968 Free PMC article.
BACKGROUND: Estimating the time since HIV infection (TSI) at population level is essential for tracking changes in the global HIV epidemic. ...It performs equally well for all major HIV subtypes based on data from African and European cohorts. CONCLUSI …
BACKGROUND: Estimating the time since HIV infection (TSI) at population level is essential for tracking changes in the global HIV …
Population pharmacokinetics of bictegravir in real-world people with HIV.
Ekobena P, Briki M, Dao K, Marzolini C, Andre P, Buclin T, Cavassini M, Guidi M, Thoueille P; Swiss HIV Cohort Study. Ekobena P, et al. J Antimicrob Chemother. 2025 Oct 3;80(10):2782-2789. doi: 10.1093/jac/dkaf297. J Antimicrob Chemother. 2025. PMID: 40798866 Free PMC article.
This study aimed to characterize bictegravir population PK in people with HIV (PWH) and to identify covariates affecting its disposition. METHODS: Bictegravir concentrations were obtained from PWH as part of a therapeutic drug monitoring (TDM) follow-up performed at the La …
This study aimed to characterize bictegravir population PK in people with HIV (PWH) and to identify covariates affecting its disposit …
Trends in Costs for HIV Care During a Hepatitis C Virus Early Treatment and Elimination Program: A Data Linkage Study of Claims and Swiss HIV Cohort Study Data.
Aghlmandi S, Schmidlin K, Huber C, Godet P, Kusejko K, Stoeckle M, Cavassini M, Günthard HF, Bernasconi E, Calmy A, Schmid P, Staehelin C, Labhardt ND, Bucher HC; Swiss HIV Cohort Study. Aghlmandi S, et al. Open Forum Infect Dis. 2025 Jul 16;12(8):ofaf410. doi: 10.1093/ofid/ofaf410. eCollection 2025 Aug. Open Forum Infect Dis. 2025. PMID: 40756653 Free PMC article.
BACKGROUND: In Switzerland detailed individual patient data are lacking on trends in health care costs, major drivers of costs, and the contribution of breakthrough innovations, such as direct-acting agents (DAAs) for the treatment of chronic hepatitis C virus (HCV) infection in …
BACKGROUND: In Switzerland detailed individual patient data are lacking on trends in health care costs, major drivers of costs, and the cont …
Leukocyte count and new-onset diabetes mellitus in people with HIV: A longitudinal study.
Meyer SC, Klein Z, Schoepf IC, Thorball CW, Labarile M, Kootstra NA, Reiss P, Ryom L, Braun DL, Thurnheer MC, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Marinosci A, Fellay J, Günthard HF, Kouyos RD, Ledergerber B, Tarr PE; Swiss HIV Cohort Study. Meyer SC, et al. Among authors: fellay j. HIV Med. 2025 Oct;26(10):1585-1599. doi: 10.1111/hiv.70089. Epub 2025 Aug 1. HIV Med. 2025. PMID: 40747677 Free PMC article.
METHODS: We included participants of the Swiss HIV Cohort Study with new-onset DM (2000-2023) and matched controls. We obtained uni- and multivariable odds ratios (ORs) for DM, based on traditional and HIV-related DM risk factors, leukocyte count and potentia …
METHODS: We included participants of the Swiss HIV Cohort Study with new-onset DM (2000-2023) and matched controls. We obtaine …
249 results