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1999 1
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2020 3
2022 2
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Page 1
Contribution of Innate Lymphoid Cells in Supplementing Cytokines Produced by CD4+ T Cells During Acute and Chronic SIV Infection of the Colon.
Ferguson N, Cogswell A, Barker E. Ferguson N, et al. AIDS Res Hum Retroviruses. 2022 Jun 30. doi: 10.1089/AID.2022.0007. Online ahead of print. AIDS Res Hum Retroviruses. 2022. PMID: 35459417
HIV/SIV (simian immunodeficiency virus) infection leads to a loss of CD4(+) T helper (Th) cells in number and function that begins during the acute phase and persists through the chronic phase of infection. In particular, there is a drastic decrease of Th17 and Th22 cells
HIV/SIV (simian immunodeficiency virus) infection leads to a loss of CD4(+) T helper (Th) cells in number and function that begins du
Presence of Natural Killer B Cells in Simian Immunodeficiency Virus-Infected Colon That Have Properties and Functions Similar to Those of Natural Killer Cells and B Cells but Are a Distinct Cell Population.
Cogswell A, Jo S, Ferguson N, Gupta K, Barker E. Cogswell A, et al. Among authors: ferguson n. J Virol. 2022 Apr 13;96(7):e0023522. doi: 10.1128/jvi.00235-22. Epub 2022 Mar 21. J Virol. 2022. PMID: 35311549 Free PMC article.
IMPORTANCE There is low-level but significant mucosal inflammation in the gastrointestinal tract secondary to human immunodeficiency virus (HIV) infection that has long-term consequences for the infected host. This inflammation most likely originates from the immune respon …
IMPORTANCE There is low-level but significant mucosal inflammation in the gastrointestinal tract secondary to human immunodeficiency virus ( …
Chronic morphine administration differentially modulates viral reservoirs in SIVmac251 infected rhesus macaque model.
Acharya A, Olwenyi OA, Thurman M, Pandey K, Morsey BM, Lamberty B, Ferguson N, Callen S, Fang Q, Buch SJ, Fox HS, Byrareddy SN. Acharya A, et al. Among authors: ferguson n. J Virol. 2020 Dec 16;95(5):e01657-20. doi: 10.1128/JVI.01657-20. Online ahead of print. J Virol. 2020. PMID: 33328304 Free PMC article.
The findings from this pre-clinical model will serve as a tool for screening therapeutic strategies to reduce/eliminate HIV reservoirs in opioid dependent PLWH.IMPORTANCE Identification and clearance of HIV reservoirs is a major challenge in achieving a cure for …
The findings from this pre-clinical model will serve as a tool for screening therapeutic strategies to reduce/eliminate HIV reservoir …
Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study.
Hogan AB, Jewell BL, Sherrard-Smith E, Vesga JF, Watson OJ, Whittaker C, Hamlet A, Smith JA, Winskill P, Verity R, Baguelin M, Lees JA, Whittles LK, Ainslie KEC, Bhatt S, Boonyasiri A, Brazeau NF, Cattarino L, Cooper LV, Coupland H, Cuomo-Dannenburg G, Dighe A, Djaafara BA, Donnelly CA, Eaton JW, van Elsland SL, FitzJohn RG, Fu H, Gaythorpe KAM, Green W, Haw DJ, Hayes S, Hinsley W, Imai N, Laydon DJ, Mangal TD, Mellan TA, Mishra S, Nedjati-Gilani G, Parag KV, Thompson HA, Unwin HJT, Vollmer MAC, Walters CE, Wang H, Wang Y, Xi X, Ferguson NM, Okell LC, Churcher TS, Arinaminpathy N, Ghani AC, Walker PGT, Hallett TB. Hogan AB, et al. Among authors: ferguson nm. Lancet Glob Health. 2020 Sep;8(9):e1132-e1141. doi: 10.1016/S2214-109X(20)30288-6. Epub 2020 Jul 13. Lancet Glob Health. 2020. PMID: 32673577 Free PMC article.
FINDINGS: In high-burden settings, deaths due to HIV, tuberculosis, and malaria over 5 years could increase by up to 10%, 20%, and 36%, respectively, compared with if there was no COVID-19 pandemic. The greatest impact on HIV was estimated to be from interruption to …
FINDINGS: In high-burden settings, deaths due to HIV, tuberculosis, and malaria over 5 years could increase by up to 10%, 20%, and 36 …
Presence of Inflammatory Group I and III Innate Lymphoid Cells in the Colon of Simian Immunodeficiency Virus-Infected Rhesus Macaques.
Cogswell A, Ferguson N, Barker E. Cogswell A, et al. Among authors: ferguson n. J Virol. 2020 Apr 16;94(9):e01914-19. doi: 10.1128/JVI.01914-19. Print 2020 Apr 16. J Virol. 2020. PMID: 32051277 Free PMC article.
The expression of IFN-gamma/TNF-alpha by ILCs and NK cells combined likely triggers a pathway that contributes to chronic mucosal inflammation, GI barrier breakdown, and microbial translocation within the context of SIV/HIV infection.IMPORTANCE There is a slow yet signific …
The expression of IFN-gamma/TNF-alpha by ILCs and NK cells combined likely triggers a pathway that contributes to chronic mucosal inflammati …
Mathematical prediction in infection.
Ferguson NM. Ferguson NM. Medicine (Abingdon). 2009 Oct;37(10):507-509. doi: 10.1016/j.mpmed.2009.07.004. Epub 2009 Sep 19. Medicine (Abingdon). 2009. PMID: 32288567 Free PMC article. Review.
This chapter concludes with a brief review of the recent application of mathematical models to a wide range of emerging human or animal epidemics, most notably the spread of HIV in Africa, the 2001 foot and mouth epidemic in British livestock, bioterrorism threats such as …
This chapter concludes with a brief review of the recent application of mathematical models to a wide range of emerging human or animal epid …
Modelling the impact of antiretroviral use in resource-poor settings.
Baggaley RF, Garnett GP, Ferguson NM. Baggaley RF, et al. Among authors: ferguson nm. PLoS Med. 2006 Apr;3(4):e124. doi: 10.1371/journal.pmed.0030124. Epub 2006 Mar 14. PLoS Med. 2006. PMID: 16519553 Free PMC article.
Mathematical models can explore the potential impacts of various treatment strategies, including timing of treatment initiation and provision of laboratory monitoring facilities, to complement evidence from pilot programmes. METHODS AND FINDINGS: A deterministic model of HIV
Mathematical models can explore the potential impacts of various treatment strategies, including timing of treatment initiation and provisio …
23 results