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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 4
1998 3
1999 14
2000 7
2001 7
2002 15
2003 20
2004 17
2005 18
2006 17
2007 8
2008 8
2009 11
2010 4
2011 7
2012 9
2013 8
2014 5
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2017 4
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2021 3
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203 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Antihistamine effects and safety of fexofenadine: a systematic review and Meta-analysis of randomized controlled trials.
Huang CZ, Jiang ZH, Wang J, Luo Y, Peng H. Huang CZ, et al. BMC Pharmacol Toxicol. 2019 Nov 29;20(1):72. doi: 10.1186/s40360-019-0363-1. BMC Pharmacol Toxicol. 2019. PMID: 31783781 Free PMC article.
When compared with placebo, fexofenadine produced more significant antihistamine effects. CONCLUSIONS: Fexofenadine has a positive antihistamine effect, which is probably no worse than the second-generation antihistamines. ...Therefore, fexofenadine may be wo …
When compared with placebo, fexofenadine produced more significant antihistamine effects. CONCLUSIONS: Fexofenadine has a posi …
Second-generation antihistamines: a comparative review.
Slater JW, Zechnich AD, Haxby DG. Slater JW, et al. Drugs. 1999 Jan;57(1):31-47. doi: 10.2165/00003495-199957010-00004. Drugs. 1999. PMID: 9951950
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadine, ketotifen, loratadine, mizolastine and terfenadine, for significant features that affect choice. ...
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadin …
Bioequivalence of 2 Pediatric Formulations of Fexofenadine Hydrochloride Oral Suspension.
Rauch C, Lucio L, De Fer BB, Lheritier-Barrand M. Rauch C, et al. Clin Pharmacol Drug Dev. 2023 Dec;12(12):1194-1203. doi: 10.1002/cpdd.1311. Epub 2023 Sep 1. Clin Pharmacol Drug Dev. 2023. PMID: 37655364 Clinical Trial.
Plasma concentrations of fexofenadine were similar following the administration of a single dose of each formulation. ...There were no serious adverse events (AEs) or study discontinuations due to treatment-emergent AEs with either fexofenadine HCl formulation. The …
Plasma concentrations of fexofenadine were similar following the administration of a single dose of each formulation. ...There were n …
Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers.
Misaka S, Ono Y, Taudte RV, Hoier E, Ogata H, Ono T, König J, Watanabe H, Fromm MF, Shimomura K. Misaka S, et al. Clin Pharmacol Ther. 2022 Sep;112(3):627-634. doi: 10.1002/cpt.2682. Epub 2022 Jun 29. Clin Pharmacol Ther. 2022. PMID: 35678032 Free PMC article. Clinical Trial.
There were no differences in time to maximum plasma concentration and the elimination half-life of fexofenadine between phases. Fexofenadine was confirmed to be a substrate of OATP1A2, and EGCG (100 and 1,000 muM) and GTE (0.1 and 1 mg/mL) inhibited OATP1A2-mediated …
There were no differences in time to maximum plasma concentration and the elimination half-life of fexofenadine between phases. Fe …
Repurposing fexofenadine as a promising candidate for diabetic kidney disease: randomized clinical trial.
El-Fatatry BM, El-Haggar SM, Ibrahim OM, Shalaby KH. El-Fatatry BM, et al. Int Urol Nephrol. 2024 Apr;56(4):1395-1402. doi: 10.1007/s11255-023-03804-w. Epub 2023 Sep 23. Int Urol Nephrol. 2024. PMID: 37741921 Free PMC article. Clinical Trial.
Patients were randomized into two groups, the fexofenadine group (n = 30): received ramipril plus fexofenadine, and the control group (n = 31): received ramipril only for six months. ...This reduction was not reported in the fexofenadine group. Fexofenadin …
Patients were randomized into two groups, the fexofenadine group (n = 30): received ramipril plus fexofenadine, and the contro …
Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.
Compalati E, Baena-Cagnani R, Penagos M, Badellino H, Braido F, Gómez RM, Canonica GW, Baena-Cagnani CE. Compalati E, et al. Int Arch Allergy Immunol. 2011;156(1):1-15. doi: 10.1159/000321896. Int Arch Allergy Immunol. 2011. PMID: 21969990
The aim of this study is to assess for the first time the efficacy and safety of fexofenadine in the treatment of AR by means of a meta-analytic analysis of existing RCTs. ...All of these values encourage the recommendation of fexofenadine for AR. Further research f …
The aim of this study is to assess for the first time the efficacy and safety of fexofenadine in the treatment of AR by means of a me …
Comparative Efficacy and Acceptability of Licensed Dose Second-Generation Antihistamines in Chronic Spontaneous Urticaria: A Network Meta-Analysis.
Phinyo P, Koompawichit P, Nochaiwong S, Tovanabutra N, Chiewchanvit S, Chuamanochan M. Phinyo P, et al. J Allergy Clin Immunol Pract. 2021 Feb;9(2):956-970.e57. doi: 10.1016/j.jaip.2020.08.055. Epub 2020 Sep 8. J Allergy Clin Immunol Pract. 2021. PMID: 32916325
RESULTS: We identified and included 22 RCTs with 3943 patients for evidence synthesis. Olopatadine, fexofenadine, bilastine, rupatadine, and levocetirizine were more efficacious than placebo in TSS. ...The acceptability of all included sgAHs was not inferior to the placebo …
RESULTS: We identified and included 22 RCTs with 3943 patients for evidence synthesis. Olopatadine, fexofenadine, bilastine, rupatadi …
Fexofenadine reduces nasal congestion in perennial allergic rhinitis.
Ciprandi G, Cosentino C, Milanese M, Mondino C, Canonica GW. Ciprandi G, et al. Allergy. 2001 Nov;56(11):1068-70. doi: 10.1034/j.1398-9995.2001.00191.x. Allergy. 2001. PMID: 11703220 Clinical Trial.
Thirty-one subjects with PAR were enrolled and received double-blind medication: fexofenadine 120 or 180 mg, or placebo, once a day for 28 days. RESULTS: The total symptom score was reduced by fexofenadine (both dosages) at V2 (P=0.007), whereas placebo did not modi …
Thirty-one subjects with PAR were enrolled and received double-blind medication: fexofenadine 120 or 180 mg, or placebo, once a day f …
Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
Nelson HS, Reynolds R, Mason J. Nelson HS, et al. Ann Allergy Asthma Immunol. 2000 May;84(5):517-22. doi: 10.1016/S1081-1206(10)62515-X. Ann Allergy Asthma Immunol. 2000. PMID: 10831005 Clinical Trial.
BACKGROUND: Fexofenadine is a nonsedating antihistamine approved for treatment of seasonal allergic rhinitis. ...Additionally, patients receiving fexofenadine experienced significantly less interference with sleep and daily activities than patients receiving placebo …
BACKGROUND: Fexofenadine is a nonsedating antihistamine approved for treatment of seasonal allergic rhinitis. ...Additionally, patien …
Bioavailability assessment of fexofenadine and montelukast in a fixed-dose combination tablet versus the components administered simultaneously.
Everardo PG, Magdalena GS, Maria Elena GP, Vanessa CM, Gabriela SC. Everardo PG, et al. Allergol Immunopathol (Madr). 2021 Jul 1;49(4):15-25. doi: 10.15586/aei.v49i4.89. eCollection 2021. Allergol Immunopathol (Madr). 2021. PMID: 34224214 Clinical Trial.
This study aimed to evaluate the bioequivalence of fexofenadine and montelukast in a fixed-dose combination tablet versus the components administered simultaneously. MATERIALS AND METHODS: An open, randomized, 22 crossover study was performed in 78 healthy volunteers. F …
This study aimed to evaluate the bioequivalence of fexofenadine and montelukast in a fixed-dose combination tablet versus the compone …
203 results