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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1994 1
1995 1
1996 4
1998 3
1999 2
2000 2
2001 5
2002 14
2003 8
2004 11
2005 11
2006 11
2007 21
2008 21
2009 18
2010 23
2011 37
2012 23
2013 16
2014 28
2015 32
2016 36
2017 32
2018 31
2019 31
2020 49
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2023 60
2024 50
2025 100
2026 107

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820 results

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Page 1
The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome.
Goldenberg DL. Goldenberg DL. Expert Rev Neurother. 2025 Aug;25(8):973-989. doi: 10.1080/14737175.2025.2516097. Epub 2025 Jun 13. Expert Rev Neurother. 2025. PMID: 40512228 Review.
These symptoms are not related to another disease or organ damage and are similar to those in fibromyalgia and myslgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). AREAS COVERED: The similar clinical and pathophysiological features and management of long COVID, …
These symptoms are not related to another disease or organ damage and are similar to those in fibromyalgia and myslgic encephalomyeli …
Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update.
Siracusa R, Paola RD, Cuzzocrea S, Impellizzeri D. Siracusa R, et al. Int J Mol Sci. 2021 Apr 9;22(8):3891. doi: 10.3390/ijms22083891. Int J Mol Sci. 2021. PMID: 33918736 Free PMC article. Review.
It is known that fibromyalgia is caused by a central sensitization phenomenon characterized by the dysfunction of neuro-circuits, which involves the perception, transmission and processing of afferent nociceptive stimuli, with the prevalent manifestation of p …
It is known that fibromyalgia is caused by a central sensitization phenomenon characterized by the dysfunction of neuro …
Effectiveness of Pain Neuroscience Education in Patients with Chronic Musculoskeletal Pain and Central Sensitization: A Systematic Review.
Lepri B, Romani D, Storari L, Barbari V. Lepri B, et al. Int J Environ Res Public Health. 2023 Feb 24;20(5):4098. doi: 10.3390/ijerph20054098. Int J Environ Res Public Health. 2023. PMID: 36901108 Free PMC article.
OBJECTIVE: To collect the available evidence about the effectiveness of pain neuroscience education (PNE) on pain, disability, and psychosocial factors in patients with chronic musculoskeletal (MSK) pain and central sensitization (CS). METHODS: A systematic review w …
OBJECTIVE: To collect the available evidence about the effectiveness of pain neuroscience education (PNE) on pain, disability, and psychosoc …
Pain Management and Rehabilitation for Central Sensitization in Temporomandibular Disorders: A Comprehensive Review.
Ferrillo M, Giudice A, Marotta N, Fortunato F, Di Venere D, Ammendolia A, Fiore P, de Sire A. Ferrillo M, et al. Int J Mol Sci. 2022 Oct 12;23(20):12164. doi: 10.3390/ijms232012164. Int J Mol Sci. 2022. PMID: 36293017 Free PMC article. Review.
In this context, myogenous TMD may present overlapping features with other disorders, such as fibromyalgia and primary headaches, characterized by chronic primary pain related to dysfunction of the central nervous system (CNS), probably through the …
In this context, myogenous TMD may present overlapping features with other disorders, such as fibromyalgia and primary headaches, cha …
Central sensitization in fibromyalgia? A systematic review on structural and functional brain MRI.
Cagnie B, Coppieters I, Denecker S, Six J, Danneels L, Meeus M. Cagnie B, et al. Semin Arthritis Rheum. 2014 Aug;44(1):68-75. doi: 10.1016/j.semarthrit.2014.01.001. Epub 2014 Jan 8. Semin Arthritis Rheum. 2014. PMID: 24508406
OBJECTIVES: The aim of the present study was to systematically review the literature addressing pain-induced changes in the brain related to central sensitization in patients with fibromyalgia (FM) using specific functional (rs-fMRI and fMRI) and structural ( …
OBJECTIVES: The aim of the present study was to systematically review the literature addressing pain-induced changes in the brain related to …
Magnesium and Pain.
Shin HJ, Na HS, Do SH. Shin HJ, et al. Nutrients. 2020 Jul 23;12(8):2184. doi: 10.3390/nu12082184. Nutrients. 2020. PMID: 32718032 Free PMC article. Review.
In terms of antinociceptive action, the main mode of action of magnesium involves its antagonist action at the N-methyl-d-aspartate (NMDA) receptor, which prevents central sensitization and attenuates preexisting pain hypersensitivity. Given the pivotal function of …
In terms of antinociceptive action, the main mode of action of magnesium involves its antagonist action at the N-methyl-d-aspartate (NMDA) r …
What we know about primary dysmenorrhea today: a critical review.
Iacovides S, Avidon I, Baker FC. Iacovides S, et al. Hum Reprod Update. 2015 Nov-Dec;21(6):762-78. doi: 10.1093/humupd/dmv039. Epub 2015 Sep 7. Hum Reprod Update. 2015. PMID: 26346058 Review.
In combination with the word 'dysmenorrhea' one or more of the following search terms were used to obtain articles published in peer-reviewed journals only: pain, risk factors, etiology, experimental pain, clinical pain, adenomyosis, chronic pain, women, menstrual cycle, hyperalg …
In combination with the word 'dysmenorrhea' one or more of the following search terms were used to obtain articles published in peer-reviewe …
Acupressure attenuates fibromyalgia central sensitization via MAPK phosphorylation-mediated neuroinflammation regulation.
Liu K, Lin Y, Rao T, Huang Y, Kan Y, Liao J. Liu K, et al. J Orthop Surg Res. 2025 Jul 8;20(1):622. doi: 10.1186/s13018-025-05986-8. J Orthop Surg Res. 2025. PMID: 40629417 Free PMC article.
This study investigates how ACP modulates central sensitization and inflammatory pathways in a rat model of FM. METHODS: An FM rat model was developed to evaluate the efficacy of ACP therapy. ...CONCLUSION: ACP exerts multimodal therapeutic effects on FMS through du …
This study investigates how ACP modulates central sensitization and inflammatory pathways in a rat model of FM. METHODS: An FM …
Central sensitization in fibromyalgia and other musculoskeletal disorders.
Arendt-Nielsen L, Graven-Nielsen T. Arendt-Nielsen L, et al. Curr Pain Headache Rep. 2003 Oct;7(5):355-61. doi: 10.1007/s11916-003-0034-0. Curr Pain Headache Rep. 2003. PMID: 12946288 Review.
Increased muscle sensitivity is manifested as pain evoked by a normally non-nociceptive stimulus (allodynia), increased pain intensity evoked by nociceptive stimuli (hyperalgesia), or increased referred pain areas with associated somatosensory changes. Some manifestations of s …
Increased muscle sensitivity is manifested as pain evoked by a normally non-nociceptive stimulus (allodynia), increased pain intensity evoke …
820 results