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225 results

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Page 1
Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update.
Siracusa R, Paola RD, Cuzzocrea S, Impellizzeri D. Siracusa R, et al. Int J Mol Sci. 2021 Apr 9;22(8):3891. doi: 10.3390/ijms22083891. Int J Mol Sci. 2021. PMID: 33918736 Free PMC article. Review.
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain, often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations in sleep and mood. ...It is known that fibromyalgia is caused by a central …
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain, often accompanied by other symptoms, …
The concept of nociplastic pain-where to from here?
Kosek E. Kosek E. Pain. 2024 Nov 1;165(11S):S50-S57. doi: 10.1097/j.pain.0000000000003305. Pain. 2024. PMID: 39560415 Review.
Peripheral and/or central sensitization, manifesting as allodynia and hyperalgesia, is typically present, although not specific for nociplastic pain. ...A major challenge is to unravel pathophysiological mechanisms driving altered nociception in patients suff …
Peripheral and/or central sensitization, manifesting as allodynia and hyperalgesia, is typically present, although not specifi …
Neurobiology of fibromyalgia and chronic widespread pain.
Sluka KA, Clauw DJ. Sluka KA, et al. Neuroscience. 2016 Dec 3;338:114-129. doi: 10.1016/j.neuroscience.2016.06.006. Epub 2016 Jun 9. Neuroscience. 2016. PMID: 27291641 Free PMC article. Review.
The underlying mechanisms, in both human and animal studies, for the continued pain in individuals with fibromyalgia will be explored in this review. There is a substantial amount of support for alterations of central nervous system nociceptive …
The underlying mechanisms, in both human and animal studies, for the continued pain in individuals with fibromyalgia will be e …
Current understanding of nociplastic pain.
Yoo YM, Kim KH. Yoo YM, et al. Korean J Pain. 2024 Apr 1;37(2):107-118. doi: 10.3344/kjp.23326. Epub 2024 Mar 20. Korean J Pain. 2024. PMID: 38504389 Free PMC article.
Augmented central nervous system pain and sensory processing with altered pain modulation are suggested to be the mechanism of nociplastic pain. ...These central sensitization pain syndromes are overlapped to p …
Augmented central nervous system pain and sensory processing with altered pain modulation are sugg …
How to explain central sensitization to patients with 'unexplained' chronic musculoskeletal pain: practice guidelines.
Nijs J, Paul van Wilgen C, Van Oosterwijck J, van Ittersum M, Meeus M. Nijs J, et al. Man Ther. 2011 Oct;16(5):413-8. doi: 10.1016/j.math.2011.04.005. Epub 2011 May 31. Man Ther. 2011. PMID: 21632273 Free article.
Central sensitization provides an evidence-based explanation for many cases of 'unexplained' chronic musculoskeletal pain. ...Pain physiology education is indicated when: 1) the clinical picture is characterized and dominated by central sensi …
Central sensitization provides an evidence-based explanation for many cases of 'unexplained' chronic musculoskeletal pain …
Microglia polarization in nociplastic pain: mechanisms and perspectives.
Atta AA, Ibrahim WW, Mohamed AF, Abdelkader NF. Atta AA, et al. Inflammopharmacology. 2023 Jun;31(3):1053-1067. doi: 10.1007/s10787-023-01216-x. Epub 2023 Apr 17. Inflammopharmacology. 2023. PMID: 37069462 Free PMC article. Review.
The main pathophysiological mechanism for developing nociplastic pain is central sensitization (CS) in which pain amplification and hypersensitivity occur. Fibromyalgia is the prototypical nociplastic pain disorder, characterized by allod …
The main pathophysiological mechanism for developing nociplastic pain is central sensitization (CS) in which pain …
Fibromyalgia and Inflammation: Unrevealing the Connection.
García-Domínguez M. García-Domínguez M. Cells. 2025 Feb 13;14(4):271. doi: 10.3390/cells14040271. Cells. 2025. PMID: 39996743 Free PMC article. Review.
Fibromyalgia represents a chronic pain pathology characterized by severe musculoskeletal pain, fatigue, disturbances in sleep, and cognitive issues. ...This review investigates the intricate relationship between inflammation and fibromyalgia, analyzing …
Fibromyalgia represents a chronic pain pathology characterized by severe musculoskeletal pain, fatigue, disturbances in …
Fibromyalgia: A Review of the Pathophysiological Mechanisms and Multidisciplinary Treatment Strategies.
Jurado-Priego LN, Cueto-Ureña C, Ramírez-Expósito MJ, Martínez-Martos JM. Jurado-Priego LN, et al. Biomedicines. 2024 Jul 11;12(7):1543. doi: 10.3390/biomedicines12071543. Biomedicines. 2024. PMID: 39062116 Free PMC article. Review.
Fibromyalgia is a syndrome characterized by chronic widespread musculoskeletal pain, which may or may not be associated with muscle or joint stiffness, accompanied by other symptoms such as fatigue, sleep disturbances, anxiety, and depression. ...Although the pathop …
Fibromyalgia is a syndrome characterized by chronic widespread musculoskeletal pain, which may or may not be associated with m …
Fibromyalgia.
Bhargava J, Goldin J. Bhargava J, et al. 2025 Jan 31. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2025 Jan 31. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 31082018 Free Books & Documents.
Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal pain, often accompanied by fatigue, cognitive dysfunction, a variety of somatic complaints, and psychiatric disturbances such as depression and anxiety. ...The disorder involv …
Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal pain, often accompanied by fatigue, …
Fibromyalgia syndrome: epidemiology, diagnosis and treatment.
Kocyigit BF, Akyol A. Kocyigit BF, et al. Reumatologia. 2022;60(6):413-421. doi: 10.5114/reum.2022.123671. Epub 2022 Dec 30. Reumatologia. 2022. PMID: 36683836 Free PMC article.
Fibromyalgia syndrome (FMS) profoundly impacts patients' quality of life with its symptoms and clinical signs. ...Although its etiopathogenesis has not been fully elucidated, various hypotheses have been proposed that central sensitization is at the core of t …
Fibromyalgia syndrome (FMS) profoundly impacts patients' quality of life with its symptoms and clinical signs. ...Although its etiopa …
225 results