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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 3
2007 9
2008 19
2009 24
2010 20
2011 18
2012 14
2013 19
2014 11
2015 13
2016 23
2017 17
2018 14
2019 15
2020 22
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270 results

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Page 1
Unraveling the skin; a comprehensive review of atopic dermatitis, current understanding, and approaches.
Afshari M, Kolackova M, Rosecka M, Čelakovská J, Krejsek J. Afshari M, et al. Front Immunol. 2024 Mar 4;15:1361005. doi: 10.3389/fimmu.2024.1361005. eCollection 2024. Front Immunol. 2024. PMID: 38500882 Free PMC article. Review.
Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease characterized by red pruritic skin lesions, xerosis, ichthyosis, and skin pain. ...
Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease characterized by red pruritic skin lesions, xe …
IgE sensitization in relation to preschool eczema and filaggrin mutation.
Johansson EK, Bergström A, Kull I, Lind T, Söderhäll C, van Hage M, Wickman M, Ballardini N, Wahlgren CF. Johansson EK, et al. J Allergy Clin Immunol. 2017 Dec;140(6):1572-1579.e5. doi: 10.1016/j.jaci.2017.04.008. Epub 2017 Apr 26. J Allergy Clin Immunol. 2017. PMID: 28456621
IgE sensitization can occur through an impaired skin barrier. Filaggrin gene (FLG) mutation is associated with eczema and possibly also with IgE sensitization. ...FLG mutation and PSE were not effect modifiers for the association between IgE sensitizat …
IgE sensitization can occur through an impaired skin barrier. Filaggrin gene (FLG) mutation is associated with eczema a …
Eczema.
Sohn A, Frankel A, Patel RV, Goldenberg G. Sohn A, et al. Mt Sinai J Med. 2011 Sep-Oct;78(5):730-9. doi: 10.1002/msj.20289. Mt Sinai J Med. 2011. PMID: 21913202 Review.
Loci on several chromosomes have been identified, including a family of epithelium-related genes called the epidermal differentiation complex on chromosome 1q21. Mutations in filaggrin, a key protein in epidermal differentiation, have also been identified in early-o …
Loci on several chromosomes have been identified, including a family of epithelium-related genes called the epidermal differentiation comple …
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Phillips R, Brown SJ, Cro S, Cornelius V, Carlsen KCL, Skjerven HO, Rehbinder EM, Lowe AJ, Dissanayake E, Shimojo N, Yonezawa K, Ohya Y, Yamamoto-Hanada K, Morita K, Axon E, Cork M, Cooke A, Van Vogt E, Schmitt J, Weidinger S, McClanahan D, Simpson E, Duley L, Askie LM, Williams HC, Boyle RJ. Kelleher MM, et al. Cochrane Database Syst Rev. 2022 Nov 14;11(11):CD013534. doi: 10.1002/14651858.CD013534.pub3. Cochrane Database Syst Rev. 2022. PMID: 36373988 Free PMC article.
Secondary outcomes included adverse events during the intervention period; eczema severity (clinician-assessed); parent report of eczema severity; time to onset of eczema; parent report of immediate food allergy; and allergic sensitisation to food or inhalant …
Secondary outcomes included adverse events during the intervention period; eczema severity (clinician-assessed); parent report of …
Recent Advancements in the Atopic Dermatitis Mechanism.
Savva M, Papadopoulos NG, Gregoriou S, Katsarou S, Papapostolou N, Makris M, Xepapadaki P. Savva M, et al. Front Biosci (Landmark Ed). 2024 Feb 22;29(2):84. doi: 10.31083/j.fbl2902084. Front Biosci (Landmark Ed). 2024. PMID: 38420827 Free article. Review.
Regarding the genetic component, the loss of function mutations encoding structural proteins such as filaggrin, a fundamental epidermal protein, and the more recently identified variations in the epidermal differentiation complex are well-established determin …
Regarding the genetic component, the loss of function mutations encoding structural proteins such as filaggrin, a funda …
Atopic eczema.
Brown SJ. Brown SJ. Clin Med (Lond). 2016 Feb;16(1):66-9. doi: 10.7861/clinmedicine.16-1-66. Clin Med (Lond). 2016. PMID: 26833520 Free PMC article.
Recent advances in understanding the aetiology of eczema have focused interest on skin barrier dysfunction as a common precursor and pathological feature. In addition, genetically determined skin barrier dysfunction (associated with mutations in the gene encoding …
Recent advances in understanding the aetiology of eczema have focused interest on skin barrier dysfunction as a common precursor and …
Atopic eczema and the filaggrin story.
Brown SJ, Irvine AD. Brown SJ, et al. Semin Cutan Med Surg. 2008 Jun;27(2):128-37. doi: 10.1016/j.sder.2008.04.001. Semin Cutan Med Surg. 2008. PMID: 18620134 Review.
The discovery that null mutations in the filaggrin gene (FLG) are associated with atopic eczema represents the single most significant breakthrough in understanding the genetic basis of this complex disorder. ...This review aims to summarize the current state …
The discovery that null mutations in the filaggrin gene (FLG) are associated with atopic eczema represents the single m …
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.
Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJ, O'Regan GM, Watson RM, Cecil JE, Bale SJ, Compton JG, DiGiovanna JJ, Fleckman P, Lewis-Jones S, Arseculeratne G, Sergeant A, Munro CS, El Houate B, McElreavey K, Halkjaer LB, Bisgaard H, Mukhopadhyay S, McLean WH. Palmer CN, et al. Nat Genet. 2006 Apr;38(4):441-6. doi: 10.1038/ng1767. Epub 2006 Mar 19. Nat Genet. 2006. PMID: 16550169
Atopic disease, including atopic dermatitis (eczema), allergy and asthma, has increased in frequency in recent decades and now affects approximately 20% of the population in the developed world. ...Although most genetic studies have focused on immunological mechanisms, a p …
Atopic disease, including atopic dermatitis (eczema), allergy and asthma, has increased in frequency in recent decades and now affect …
Filaggrin failure - from ichthyosis vulgaris to atopic eczema and beyond.
McLean WH. McLean WH. Br J Dermatol. 2016 Oct;175 Suppl 2(Suppl Suppl 2):4-7. doi: 10.1111/bjd.14997. Br J Dermatol. 2016. PMID: 27667308 Free PMC article. Review.
Filaggrin is therefore essential for normal stratum corneum biogenesis and physiology. In 2006, the McLean group identified the first loss-of-function mutations in the filaggrin gene (FLG) as the cause of the common monogenic genodermatosis ichthyosis vulgari …
Filaggrin is therefore essential for normal stratum corneum biogenesis and physiology. In 2006, the McLean group identified the first …
Atopic Dermatitis Disease Complications.
Ashbaugh AG, Kwatra SG. Ashbaugh AG, et al. Adv Exp Med Biol. 2024;1447:59-67. doi: 10.1007/978-3-031-54513-9_6. Adv Exp Med Biol. 2024. PMID: 38724784
270 results