Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2009 2
2010 1
2012 1
2013 2
2014 2
2015 7
2016 5
2017 4
2018 4
2019 7
2020 4
2021 5
2022 2
2023 9
2024 2
2025 6
2026 8

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

64 results

Results by year

Filters applied: . Clear all
Page 1
Daidzein alleviates chronic restraint stress-induced depression-like behavior by regulating neuroinflammation and synaptic plasticity via microbiota-gut-brain axis.
Wang H, Nie Y, Luo Y, Sun Z, He Y, Yang J. Wang H, et al. Phytomedicine. 2025 Nov 25;148:157394. doi: 10.1016/j.phymed.2025.157394. Epub 2025 Oct 10. Phytomedicine. 2025. PMID: 41106100 Free article.
Intestinal barrier function was evaluated by histopathology and FITC-dextran detection. Neuroinflammatory responses, neuronal morphology, and plasticity were also evaluated using immunofluorescence staining, western blotting, and Nissl staining. ...These molecular c …
Intestinal barrier function was evaluated by histopathology and FITC-dextran detection. Neuroinflammatory responses, neuronal morphol …
3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus.
Sawamoto A, Okuyama S, Yamamoto K, Amakura Y, Yoshimura M, Nakajima M, Furukawa Y. Sawamoto A, et al. Molecules. 2016 Apr 23;21(4):541. doi: 10.3390/molecules21040541. Molecules. 2016. PMID: 27120588 Free PMC article.
We previously reported that the citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF) increased the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of a transient global ischemia mouse model. ...These …
We previously reported that the citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF) increased the expression of brain- …
The Low Molecular Weight Brain-derived Neurotrophic Factor Mimetics with Antidepressant-like Activity.
Gudasheva TA, Povarnina P, Tarasiuk AV, Seredenin SB. Gudasheva TA, et al. Curr Pharm Des. 2019;25(6):729-737. doi: 10.2174/1381612825666190329122852. Curr Pharm Des. 2019. PMID: 30931847 Review.
The search for new highly-effective, fast-acting antidepressant drugs is extremely relevant. Brain derived neurotrophic factor (BDNF) and signaling through its tropomyosin-related tyrosine kinase B (TrkB) receptor, represents one of the most pro …
The search for new highly-effective, fast-acting antidepressant drugs is extremely relevant. Brain derived neurotrophic …
Emphasizing roles of BDNF promoters and inducers in Alzheimer's disease for improving impaired cognition and memory.
Banerjee M, Shenoy RR. Banerjee M, et al. J Basic Clin Physiol Pharmacol. 2021 Nov 8;34(2):125-136. doi: 10.1515/jbcpp-2021-0182. eCollection 2023 Mar 1. J Basic Clin Physiol Pharmacol. 2021. PMID: 34751526 Review.
Brain-derived neurotrophic factor (BDNF) is a crucial neurotrophic factor adding to neurons' development and endurance. ...This review paper discusses the aforesaid points along with inducers of BDNF. Drugs and herbals promo …
Brain-derived neurotrophic factor (BDNF) is a crucial neurotrophic factor adding to neurons …
Yueju pill and its active component- Myricetin attenuate the reinstatement of methamphetamine-seeking behavior in mice.
Du Y, Fan S, Yang X, Ma W, Li S, Xu Y, Li C, Chen S, Wang Y, Wang M, Ma T, Zhang J. Du Y, et al. Int Immunopharmacol. 2025 Dec 3;166:115601. doi: 10.1016/j.intimp.2025.115601. Epub 2025 Sep 26. Int Immunopharmacol. 2025. PMID: 41014771
Furthermore, YJ prevented METH-induced aberrant potentiation of glutamatergic transmission and restored physiological synaptic plasticity, likely mediated by upregulated expression of brain-derived neurotrophic factor (BDNF) and postsynap …
Furthermore, YJ prevented METH-induced aberrant potentiation of glutamatergic transmission and restored physiological synaptic plasticity …
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-kappaB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
Sun Y, Zhang H, Wu Z, Yu X, Yin Y, Qian S, Wang Z, Huang J, Wang W, Liu T, Xue W, Chen G. Sun Y, et al. ACS Chem Neurosci. 2021 Sep 15;12(18):3387-3396. doi: 10.1021/acschemneuro.1c00371. Epub 2021 Sep 1. ACS Chem Neurosci. 2021. PMID: 34469122
The results showed a single dose of Qc (10 mg/kg) produced an antidepressant-like effect at 2 h postadministration and lasted for at least 3 days. The expressions of neuroplasticity signaling molecules of pCREB/BDNF/PSD95/Synapsin1 were upregulated at 2 h, and ERK s …
The results showed a single dose of Qc (10 mg/kg) produced an antidepressant-like effect at 2 h postadministration and lasted for at least 3 …
Dietary Flavonoids Interaction with CREB-BDNF Pathway: An Unconventional Approach for Comprehensive Management of Epilepsy.
Sharma P, Kumar A, Singh D. Sharma P, et al. Curr Neuropharmacol. 2019;17(12):1158-1175. doi: 10.2174/1570159X17666190809165549. Curr Neuropharmacol. 2019. PMID: 31400269 Free PMC article. Review.
cAMP response element binding protein (CREB) is a key transcriptional regulator that regulates the transcription of genes related with neuronal differentiation, synaptic plasticity, learning and memory. Brain derived neurotrophic factor ( …
cAMP response element binding protein (CREB) is a key transcriptional regulator that regulates the transcription of genes related with ne …
VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism.
Lin WJ, Jiang C, Sadahiro M, Bozdagi O, Vulchanova L, Alberini CM, Salton SR. Lin WJ, et al. J Neurosci. 2015 Jul 15;35(28):10343-56. doi: 10.1523/JNEUROSCI.0584-15.2015. J Neurosci. 2015. PMID: 26180209 Free PMC article.
We found that hippocampal VGF expression and TLQP-62 levels were transiently induced after fear memory training and that sequestering secreted TLQP-62 peptide in the hippocampus immediately after training impaired memory formation. Reduced VGF expression was found to impai …
We found that hippocampal VGF expression and TLQP-62 levels were transiently induced after fear memory training and that sequestering secret …
Chrysin modulates the BDNF/TrkB/AKT/Creb neuroplasticity signaling pathway: Acting in the improvement of cognitive flexibility and declarative, working and aversive memory deficits caused by hypothyroidism in C57BL/6 female mice.
Bortolotto VC, Dahleh MMM, Marques LS, Borstmann SMA, Viana CE, Pinheiro FC, Balok FRM, Meichtry LB, Boeira SP, Guerra GP, Nogueira CW, Prigol M. Bortolotto VC, et al. Neuroscience. 2025 Feb 6;566:28-38. doi: 10.1016/j.neuroscience.2024.12.032. Epub 2024 Dec 19. Neuroscience. 2025. PMID: 39709060
We assessed cognitive flexibility, declarative, working, and aversive memories while analyzing the BDNF/TrkB/AKT/Creb neuroplasticity signaling pathway and synaptic function in the hippocampus and prefrontal cortex. ...Hypothyroid mice exhibited deficits in c …
We assessed cognitive flexibility, declarative, working, and aversive memories while analyzing the BDNF/TrkB/AKT/Creb neuroplastic …
Phytochemicals That Act on Synaptic Plasticity as Potential Prophylaxis against Stress-Induced Depressive Disorder.
Yoon S, Iqbal H, Kim SM, Jin M. Yoon S, et al. Biomol Ther (Seoul). 2023 Mar 1;31(2):148-160. doi: 10.4062/biomolther.2022.116. Epub 2023 Jan 25. Biomol Ther (Seoul). 2023. PMID: 36694423 Free PMC article. Review.
Depression is a neuropsychiatric disorder associated with persistent stress and disruption of neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses and reduced size of the hippocampus and prefrontal cortex. ...We further ela …
Depression is a neuropsychiatric disorder associated with persistent stress and disruption of neuronal function. Persistent stress ca …
64 results