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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 2
1985 4
1986 1
1987 3
1988 6
1989 20
1990 14
1991 27
1992 26
1993 44
1994 53
1995 51
1996 43
1997 49
1998 50
1999 58
2000 55
2001 57
2002 64
2003 59
2004 67
2005 76
2006 74
2007 72
2008 68
2009 81
2010 73
2011 62
2012 46
2013 66
2014 59
2015 52
2016 36
2017 27
2018 34
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2021 58
2022 49
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2024 24
2025 13

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1,680 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial.
Chollet F, Tardy J, Albucher JF, Thalamas C, Berard E, Lamy C, Bejot Y, Deltour S, Jaillard A, Niclot P, Guillon B, Moulin T, Marque P, Pariente J, Arnaud C, Loubinoux I. Chollet F, et al. Lancet Neurol. 2011 Feb;10(2):123-30. doi: 10.1016/S1474-4422(10)70314-8. Epub 2011 Jan 7. Lancet Neurol. 2011. PMID: 21216670 Clinical Trial.
A few small clinical trials suggest that fluoxetine enhances motor recovery but its clinical efficacy is unknown. We therefore aimed to investigate whether fluoxetine would enhance motor recovery if given soon after an ischaemic stroke to patients who have motor def …
A few small clinical trials suggest that fluoxetine enhances motor recovery but its clinical efficacy is unknown. We therefore aimed …
Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: Treatment for Adolescents With Depression Study (TADS) randomized controlled trial.
March J, Silva S, Petrycki S, Curry J, Wells K, Fairbank J, Burns B, Domino M, McNulty S, Vitiello B, Severe J; Treatment for Adolescents With Depression Study (TADS) Team. March J, et al. JAMA. 2004 Aug 18;292(7):807-20. doi: 10.1001/jama.292.7.807. JAMA. 2004. PMID: 15315995 Clinical Trial.
Placebo and fluoxetine alone were administered double-blind; CBT alone and CBT with fluoxetine were administered unblinded. ...Compared with fluoxetine alone (P =.02) and CBT alone (P =.01), treatment of fluoxetine with CBT was superior. ...
Placebo and fluoxetine alone were administered double-blind; CBT alone and CBT with fluoxetine were administered unblinded. .. …
The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): a randomised, double-blind, placebo-controlled, multicentre clinical trial.
Davey CG, Chanen AM, Hetrick SE, Cotton SM, Ratheesh A, Amminger GP, Koutsogiannis J, Phelan M, Mullen E, Harrison BJ, Rice S, Parker AG, Dean OM, Weller A, Kerr M, Quinn AL, Catania L, Kazantzis N, McGorry PD, Berk M. Davey CG, et al. Lancet Psychiatry. 2019 Sep;6(9):735-744. doi: 10.1016/S2215-0366(19)30215-9. Epub 2019 Jul 29. Lancet Psychiatry. 2019. PMID: 31371212 Clinical Trial.
Patients were randomly assigned (1:1) to receive CBT for 12 weeks, plus either fluoxetine or placebo. Participants began on one 20 mg capsule of fluoxetine or one placebo pill per day. ...FINDINGS: 153 participants (mean age 19.6 years [SD 2.7]) were enrolled from F …
Patients were randomly assigned (1:1) to receive CBT for 12 weeks, plus either fluoxetine or placebo. Participants began on one 20 mg …
Fluoxetine in acute treatment of children and adolescents with obsessive-compulsive disorder: a systematic review and meta-analysis.
Maneeton N, Maneeton B, Karawekpanyawong N, Woottiluk P, Putthisri S, Srisurapanon M. Maneeton N, et al. Nord J Psychiatry. 2020 Oct;74(7):461-469. doi: 10.1080/08039488.2020.1744037. Epub 2020 Apr 3. Nord J Psychiatry. 2020. PMID: 32242450
Then, the full-text versions of relevant studies were thoroughly assessed and extracted.Results: A total of 188 randomized patients in three RCTs of fluoxetine versus placebo and one RCT of fluoxetine versus citalopram were included in this review. Considering effic …
Then, the full-text versions of relevant studies were thoroughly assessed and extracted.Results: A total of 188 randomized patients in three …
Fluoxetine modulates the pro-inflammatory process of IL-6, IL-1beta and TNF-alpha levels in individuals with depression: a systematic review and meta-analysis.
García-García ML, Tovilla-Zárate CA, Villar-Soto M, Juárez-Rojop IE, González-Castro TB, Genis-Mendoza AD, Ramos-Méndez MÁ, López-Nárvaez ML, Saucedo-Osti AS, Ruiz-Quiñones JA, Martinez-Magaña JJ. García-García ML, et al. Psychiatry Res. 2022 Jan;307:114317. doi: 10.1016/j.psychres.2021.114317. Epub 2021 Nov 28. Psychiatry Res. 2022. PMID: 34864233
The analysis included a total of 292 individuals with major depressive disorder who received fluoxetine for a period longer than 6 weeks; additionally, IL-1beta, IL-6 or TNF-alpha levels were measured at the end of the antidepressant treatment. ...In conclusion, the pooled …
The analysis included a total of 292 individuals with major depressive disorder who received fluoxetine for a period longer than 6 we …
Comparison of fluoxetine with other selective serotonin reuptake inhibitors in the treatment of premature ejaculation: A systematic review and meta-analysis.
Liu Q, Gao H, Huang Y, Wang M, Jiang H, Dai Y, Zhang X. Liu Q, et al. Andrologia. 2022 Sep;54(8):e14500. doi: 10.1111/and.14500. Epub 2022 Jun 27. Andrologia. 2022. PMID: 35760074 Review.
Our meta-analysis includes a total of ten trials to investigate into the differences in treatment efficacy and safety between fluoxetine and other medicines. The findings revealed that fluoxetine was more effective than placebo in treating PE, whereas sertraline and …
Our meta-analysis includes a total of ten trials to investigate into the differences in treatment efficacy and safety between fluoxetine
Effects of chronic fluoxetine treatment on anxiety- and depressive-like behaviors in adolescent rodents - systematic review and meta-analysis.
Kryst J, Majcher-Maślanka I, Chocyk A. Kryst J, et al. Pharmacol Rep. 2022 Oct;74(5):920-946. doi: 10.1007/s43440-022-00420-w. Epub 2022 Sep 24. Pharmacol Rep. 2022. PMID: 36151445 Free PMC article. Review.
No significant effects of chronic adolescent fluoxetine on depression-like behavior were reported in naive animals, while in stress-exposed rodents chronic adolescent fluoxetine significantly decreased immobility time in the forced swim test compared to vehicle. ... …
No significant effects of chronic adolescent fluoxetine on depression-like behavior were reported in naive animals, while in stress-e …
The efficacy and safety of fluoxetine versus placebo for stroke recovery: a meta-analysis of randomized controlled trials.
Wu J, Qin G. Wu J, et al. Int J Clin Pharm. 2023 Aug;45(4):839-846. doi: 10.1007/s11096-023-01573-1. Epub 2023 Apr 20. Int J Clin Pharm. 2023. PMID: 37081168 Review.
BACKGROUND: Fluoxetine is one of the selective serotonin reuptake inhibitors that can improve motor and function recovery after a stroke. ...There were no significant differences between the groups regarding gastrointestinal adverse reactions (P > 0.05), drowsiness (P & …
BACKGROUND: Fluoxetine is one of the selective serotonin reuptake inhibitors that can improve motor and function recovery after a str …
Can fluoxetine influence orthodontic tooth movement? A systematic review and meta-analysis of studies on animal models.
Javed F, Ahmed ZU, Rossouw PE, Romanos GE. Javed F, et al. Int Orthod. 2025 Jun;23(2):100960. doi: 10.1016/j.ortho.2024.100960. Epub 2024 Dec 12. Int Orthod. 2025. PMID: 39672088 Review.
INTRODUCTION: Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine adversely affect bone mineral density (BMD) and turnover, thereby increasing the risk of fractures. ...Rats in the experimental group underwent OTM with adjunct fluoxetine injections at …
INTRODUCTION: Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine adversely affect bone mineral density (BMD) and turn …
Effects of the selective serotonin reuptake inhibitor fluoxetine on glucose metabolism: A systematic review.
Zhang Z, Du Y, Chen L, Liu Y, Du B. Zhang Z, et al. Asian J Psychiatr. 2022 Jul;73:103092. doi: 10.1016/j.ajp.2022.103092. Epub 2022 Apr 6. Asian J Psychiatr. 2022. PMID: 35430493
This study aims to explore the effects of fluoxetine on glucose and lipid metabolism in human body. METHODS: Studies of the effects of fluoxetine on glucose and lipid metabolism were collected from the PubMed, MEDLINE and Embase databases without limiting the resear …
This study aims to explore the effects of fluoxetine on glucose and lipid metabolism in human body. METHODS: Studies of the effects o …
1,680 results