Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1992 1
1994 1
1996 1
1997 2
1999 1
2000 1
2001 2
2002 12
2003 16
2004 13
2005 14
2006 7
2007 11
2008 10
2009 22
2010 23
2011 14
2012 8
2013 11
2014 29
2015 43
2016 38
2017 54
2018 50
2019 61
2020 62
2021 72
2022 69
2023 37

Text availability

Article attribute

Article type

Publication date

Search Results

102 results

Results by year

Filters applied: . Clear all
Page 1
Senescence and cancer - role and therapeutic opportunities.
Schmitt CA, Wang B, Demaria M. Schmitt CA, et al. Among authors: demaria m. Nat Rev Clin Oncol. 2022 Oct;19(10):619-636. doi: 10.1038/s41571-022-00668-4. Epub 2022 Aug 31. Nat Rev Clin Oncol. 2022. PMID: 36045302 Free PMC article. Review.
cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.
Hong C, Schubert M, Tijhuis AE, Requesens M, Roorda M, van den Brink A, Ruiz LA, Bakker PL, van der Sluis T, Pieters W, Chen M, Wardenaar R, van der Vegt B, Spierings DCJ, de Bruyn M, van Vugt MATM, Foijer F. Hong C, et al. Among authors: spierings dcj, foijer f. Nature. 2022 Jul;607(7918):366-373. doi: 10.1038/s41586-022-04847-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705809
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions.
Secomandi L, Borghesan M, Velarde M, Demaria M. Secomandi L, et al. Among authors: demaria m. Hum Reprod Update. 2022 Feb 28;28(2):172-189. doi: 10.1093/humupd/dmab038. Hum Reprod Update. 2022. PMID: 34918084 Free PMC article. Review.
As the mean age of giving birth is increasing worldwide, prevention of age-associated infertility and pregnancy complications, along with the more frequent use of ART, become extremely important. Currently, significant research is being conducted to unravel the mechanisms …
As the mean age of giving birth is increasing worldwide, prevention of age-associated infertility and pregnancy complications, along with th …
Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome.
Chen L, Zhernakova DV, Kurilshikov A, Andreu-Sánchez S, Wang D, Augustijn HE, Vich Vila A; Lifelines Cohort Study; Weersma RK, Medema MH, Netea MG, Kuipers F, Wijmenga C, Zhernakova A, Fu J. Chen L, et al. Among authors: kuipers f. Nat Med. 2022 Nov;28(11):2333-2343. doi: 10.1038/s41591-022-02014-8. Epub 2022 Oct 10. Nat Med. 2022. PMID: 36216932 Free PMC article.
The levels of the thousands of metabolites in the human plasma metabolome are strongly influenced by an individual's genetics and the composition of their diet and gut microbiome. ...
The levels of the thousands of metabolites in the human plasma metabolome are strongly influenced by an individual's genetics and the …
Genetic instability from a single S phase after whole-genome duplication.
Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé AS, Tijhuis AE, Bernhard SV, Spierings DCJ, Simon A, Goundiam O, Hochegger H, Piel M, Foijer F, Storchová Z, Basto R. Gemble S, et al. Among authors: spierings dcj, foijer f. Nature. 2022 Apr;604(7904):146-151. doi: 10.1038/s41586-022-04578-4. Epub 2022 Mar 30. Nature. 2022. PMID: 35355016 Free PMC article.
Here we find that human cells undergo high rates of DNA damage during DNA replication in the first S phase following induction of tetraploidy. Using DNA combing and single-cell sequencing, we show that DNA replication dynamics is perturbed, generating under- and over-repli …
Here we find that human cells undergo high rates of DNA damage during DNA replication in the first S phase following induction of tet …
Nuclear chromosome locations dictate segregation error frequencies.
Klaasen SJ, Truong MA, van Jaarsveld RH, Koprivec I, Štimac V, de Vries SG, Risteski P, Kodba S, Vukušić K, de Luca KL, Marques JF, Gerrits EM, Bakker B, Foijer F, Kind J, Tolić IM, Lens SMA, Kops GJPL. Klaasen SJ, et al. Among authors: foijer f. Nature. 2022 Jul;607(7919):604-609. doi: 10.1038/s41586-022-04938-0. Epub 2022 Jul 13. Nature. 2022. PMID: 35831506 Free PMC article.
Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial.
Heerspink HJL, Radhakrishnan J, Alpers CE, Barratt J, Bieler S, Diva U, Inrig J, Komers R, Mercer A, Noronha IL, Rheault MN, Rote W, Rovin B, Trachtman H, Trimarchi H, Wong MG, Perkovic V; PROTECT Investigators. Heerspink HJL, et al. Lancet. 2023 May 13;401(10388):1584-1594. doi: 10.1016/S0140-6736(23)00569-X. Epub 2023 Apr 1. Lancet. 2023. PMID: 37015244 Clinical Trial.
Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients.
Vissers MFJM, Heuberger JAAC, Groeneveld GJ, Oude Nijhuis J, De Deyn PP, Hadi S, Harris J, Tsai RM, Cruz-Herranz A, Huang F, Tong V, Erickson R, Zhu Y, Scearce-Levie K, Hsiao-Nakamoto J, Tang X, Chang M, Fox BM, Estrada AA, Pomponio RJ, Alonso-Alonso M, Zilberstein M, Atassi N, Troyer MD, Ho C. Vissers MFJM, et al. Among authors: chang m. Clin Transl Sci. 2022 Aug;15(8):2010-2023. doi: 10.1111/cts.13317. Epub 2022 Jun 1. Clin Transl Sci. 2022. PMID: 35649245 Free PMC article. Clinical Trial.
RIPK1 is a master regulator of inflammatory signaling and cell death and increased RIPK1 activity is observed in human diseases, including Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). RIPK1 inhibition has been shown to protect against cell death in a r …
RIPK1 is a master regulator of inflammatory signaling and cell death and increased RIPK1 activity is observed in human diseases, including A …
102 results