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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1968 1
1972 1
1973 1
1977 1
1978 4
1980 1
1982 2
1984 1
1985 1
1986 5
1987 6
1988 4
1989 5
1990 5
1991 10
1992 7
1993 16
1994 9
1995 15
1996 18
1997 26
1998 16
1999 23
2000 33
2001 33
2002 40
2003 34
2004 65
2005 57
2006 47
2007 75
2008 82
2009 95
2010 116
2011 123
2012 129
2013 191
2014 182
2015 186
2016 196
2017 185
2018 161
2019 157
2020 199
2021 206
2022 85
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2,468 results
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Page 1
Fructose and hepatic insulin resistance.
Softic S, Stanhope KL, Boucher J, Divanovic S, Lanaspa MA, Johnson RJ, Kahn CR. Softic S, et al. Crit Rev Clin Lab Sci. 2020 Aug;57(5):308-322. doi: 10.1080/10408363.2019.1711360. Epub 2020 Jan 14. Crit Rev Clin Lab Sci. 2020. PMID: 31935149 Free PMC article. Review.
In this review, we present the data invoking fructose intake with development of hepatic insulin resistance in human studies and discuss the pathways by which fructose impairs hepatic insulin action in experimental animal models. First, we descr …
In this review, we present the data invoking fructose intake with development of hepatic insulin resistance in human st …
Dietary Fructose and the Metabolic Syndrome.
Taskinen MR, Packard CJ, Borén J. Taskinen MR, et al. Nutrients. 2019 Aug 22;11(9):1987. doi: 10.3390/nu11091987. Nutrients. 2019. PMID: 31443567 Free PMC article. Review.
These products comprise a large proportion of the modern diet, in particular in children, adolescents, and young adults. A large body of evidence associate consumption of fructose and other sugar-sweetened beverages with insulin resistance, intrahepatic lipid …
These products comprise a large proportion of the modern diet, in particular in children, adolescents, and young adults. A large body of evi …
Fructose metabolism and metabolic disease.
Hannou SA, Haslam DE, McKeown NM, Herman MA. Hannou SA, et al. J Clin Invest. 2018 Feb 1;128(2):545-555. doi: 10.1172/JCI96702. Epub 2018 Feb 1. J Clin Invest. 2018. PMID: 29388924 Free PMC article. Review.
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly har …
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their asso …
High Dietary Fructose: Direct or Indirect Dangerous Factors Disturbing Tissue and Organ Functions.
Zhang DM, Jiao RQ, Kong LD. Zhang DM, et al. Nutrients. 2017 Mar 29;9(4):335. doi: 10.3390/nu9040335. Nutrients. 2017. PMID: 28353649 Free PMC article. Review.
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome, disturbing tissue and organ functions. ...It is important to find the potential correlations between direct and/or indirect risk factors and healthy problems under exce …
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome, disturbing tissue and organ …
Uric Acid as a Cause of the Metabolic Syndrome.
King C, Lanaspa MA, Jensen T, Tolan DR, Sánchez-Lozada LG, Johnson RJ. King C, et al. Contrib Nephrol. 2018;192:88-102. doi: 10.1159/000484283. Epub 2018 Jan 23. Contrib Nephrol. 2018. PMID: 29393133 Review.
Experimental studies have also shown that hyperuricemia may mediate insulin resistance, fatty liver, and dyslipidemia in both fructose-dependent and fructose-independent models of metabolic syndrome. The mechanism for uric acid-induced insulin
Experimental studies have also shown that hyperuricemia may mediate insulin resistance, fatty liver, and dyslipidemia in both …
Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review.
Caliceti C, Calabria D, Roda A, Cicero AFG. Caliceti C, et al. Nutrients. 2017 Apr 18;9(4):395. doi: 10.3390/nu9040395. Nutrients. 2017. PMID: 28420204 Free PMC article. Review.
There is a direct relationship between fructose intake and serum levels of uric acid (UA), which is the final product of purine metabolism. ...Other dietary and pathophysiological factors are also related to UA production. However, the role of fructose-derived UA in …
There is a direct relationship between fructose intake and serum levels of uric acid (UA), which is the final product of purine metab …
Fructose, weight gain, and the insulin resistance syndrome.
Elliott SS, Keim NL, Stern JS, Teff K, Havel PJ. Elliott SS, et al. Am J Clin Nutr. 2002 Nov;76(5):911-22. doi: 10.1093/ajcn/76.5.911. Am J Clin Nutr. 2002. PMID: 12399260 Free article. Review.
This review explores whether fructose consumption might be a contributing factor to the development of obesity and the accompanying metabolic abnormalities observed in the insulin resistance syndrome. ...Fructose consumption induces insulin r
This review explores whether fructose consumption might be a contributing factor to the development of obesity and the accompanying m …
Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications.
Barrière DA, Noll C, Roussy G, Lizotte F, Kessai A, Kirby K, Belleville K, Beaudet N, Longpré JM, Carpentier AC, Geraldes P, Sarret P. Barrière DA, et al. Sci Rep. 2018 Jan 11;8(1):424. doi: 10.1038/s41598-017-18896-5. Sci Rep. 2018. PMID: 29323186 Free PMC article.
The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption. Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of streptozotocin (HF/HF/Stz) to emulate the long-term complications of T2DM. ...Altogether …
The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption. Here, we thus combined high-fat/high-fruc
Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome.
Dekker MJ, Su Q, Baker C, Rutledge AC, Adeli K. Dekker MJ, et al. Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E685-94. doi: 10.1152/ajpendo.00283.2010. Epub 2010 Sep 7. Am J Physiol Endocrinol Metab. 2010. PMID: 20823452 Free article. Review.
Obesity is associated with a host of metabolic challenges, collectively termed the metabolic syndrome. Fructose is a highly lipogenic sugar that has profound metabolic effects in the liver and has been associated with many of the components of the metabolic syndrome (in
Obesity is associated with a host of metabolic challenges, collectively termed the metabolic syndrome. Fructose is a highly lipogenic …
The fructose-fed rat: a review on the mechanisms of fructose-induced insulin resistance and hypertension.
Tran LT, Yuen VG, McNeill JH. Tran LT, et al. Mol Cell Biochem. 2009 Dec;332(1-2):145-59. doi: 10.1007/s11010-009-0184-4. Epub 2009 Jun 18. Mol Cell Biochem. 2009. PMID: 19536638 Review.
This animal model is used to study the relationship between insulin resistance/compensatory hyperinsulinemia and the development of hypertension. Several mechanisms have been proposed to mediate the link between insulin resistance and hypertension. In …
This animal model is used to study the relationship between insulin resistance/compensatory hyperinsulinemia and the developme …
2,468 results