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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1968 1
1972 1
1973 1
1977 1
1978 4
1980 1
1982 2
1984 1
1985 1
1986 5
1987 6
1988 4
1989 5
1990 5
1991 10
1992 7
1993 16
1994 9
1995 15
1996 18
1997 26
1998 16
1999 23
2000 33
2001 33
2002 40
2003 34
2004 65
2005 57
2006 47
2007 75
2008 82
2009 95
2010 116
2011 123
2012 129
2013 191
2014 182
2015 186
2016 195
2017 185
2018 158
2019 153
2020 133
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2,168 results
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Page 1
Dietary Fructose and the Metabolic Syndrome.
Taskinen MR, Packard CJ, Borén J. Taskinen MR, et al. Nutrients. 2019 Aug 22;11(9):1987. doi: 10.3390/nu11091987. Nutrients. 2019. PMID: 31443567 Free PMC article. Review.
These products comprise a large proportion of the modern diet, in particular in children, adolescents, and young adults. A large body of evidence associate consumption of fructose and other sugar-sweetened beverages with insulin resistance, intrahepatic lipid …
These products comprise a large proportion of the modern diet, in particular in children, adolescents, and young adults. A large body of evi …
Fructose metabolism and metabolic disease.
Hannou SA, Haslam DE, McKeown NM, Herman MA. Hannou SA, et al. J Clin Invest. 2018 Feb 1;128(2):545-555. doi: 10.1172/JCI96702. Epub 2018 Feb 1. J Clin Invest. 2018. PMID: 29388924 Free PMC article. Review.
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly har …
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their asso …
The role of fructose in metabolism and cancer.
Charrez B, Qiao L, Hebbard L. Charrez B, et al. Horm Mol Biol Clin Investig. 2015 May;22(2):79-89. doi: 10.1515/hmbci-2015-0009. Horm Mol Biol Clin Investig. 2015. PMID: 25965509 Review.
Fructose consumption has dramatically increased in the last 30 years. ...Here we present an overview of fructose metabolism and how it contrasts with that of glucose. In addition, we examine how excessive fructose consumption can affect de novo lipogenesis,
Fructose consumption has dramatically increased in the last 30 years. ...Here we present an overview of fructose metabolism an
Health implications of high-fructose intake and current research.
Dornas WC, de Lima WG, Pedrosa ML, Silva ME. Dornas WC, et al. Adv Nutr. 2015 Nov 13;6(6):729-37. doi: 10.3945/an.114.008144. Print 2015 Nov. Adv Nutr. 2015. PMID: 26567197 Free PMC article. Review.
We discuss the available data and investigate the effects of dietary fructose on risk factors associated with metabolic disorders. The evidence suggests that fructose may be a predisposing cause in the development of insulin resistance in association w …
We discuss the available data and investigate the effects of dietary fructose on risk factors associated with metabolic disorders. Th …
Fructose at the crossroads of the metabolic syndrome and obesity epidemics.
Mortera RR, Bains Y, Gugliucci A. Mortera RR, et al. Front Biosci (Landmark Ed). 2019 Jan 1;24:186-211. Front Biosci (Landmark Ed). 2019. PMID: 30468651 Review.
The specifics effects of fructose on the liver are particularly germane to the development of a vicious cycle that starts with liver steatosis driving insulin resistance. ...Directionality for the effect of fructose on metabolic syndrome is becoming cl …
The specifics effects of fructose on the liver are particularly germane to the development of a vicious cycle that starts with liver …
High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress.
Balakumar M, Raji L, Prabhu D, Sathishkumar C, Prabu P, Mohan V, Balasubramanyam M. Balakumar M, et al. Mol Cell Biochem. 2016 Dec;423(1-2):93-104. doi: 10.1007/s11010-016-2828-5. Epub 2016 Oct 3. Mol Cell Biochem. 2016. PMID: 27699590
In the context of high human consumption of fructose diets, there is an imperative need to understand how dietary fructose intake influence cellular and molecular mechanisms and thereby affect beta-cell dysfunction and insulin resistance. While evidenc …
In the context of high human consumption of fructose diets, there is an imperative need to understand how dietary fructose int …
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome.
Lim JS, Mietus-Snyder M, Valente A, Schwarz JM, Lustig RH. Lim JS, et al. Nat Rev Gastroenterol Hepatol. 2010 May;7(5):251-64. doi: 10.1038/nrgastro.2010.41. Epub 2010 Apr 6. Nat Rev Gastroenterol Hepatol. 2010. PMID: 20368739 Review.
In the first 'hit', hepatic metabolism of fructose promotes de novo lipogenesis and intrahepatic lipid, inhibition of mitochondrial beta-oxidation of long-chain fatty acids, triglyceride formation and steatosis, hepatic and skeletal muscle insulin resistance, …
In the first 'hit', hepatic metabolism of fructose promotes de novo lipogenesis and intrahepatic lipid, inhibition of mitochondrial b …
Formation of Fructose-Mediated Advanced Glycation End Products and Their Roles in Metabolic and Inflammatory Diseases.
Gugliucci A. Gugliucci A. Adv Nutr. 2017 Jan 17;8(1):54-62. doi: 10.3945/an.116.013912. Print 2017 Jan. Adv Nutr. 2017. PMID: 28096127 Free PMC article. Review.
It is metabolized by the liver, where it stimulates de novo lipogenesis. The triglycerides synthesized lead to hepatic insulin resistance and dyslipidemia. Fructose-derived advanced glycation end products (AGEs) may be involved via the Maillard reaction. ...T …
It is metabolized by the liver, where it stimulates de novo lipogenesis. The triglycerides synthesized lead to hepatic insulin res
High Dietary Fructose: Direct or Indirect Dangerous Factors Disturbing Tissue and Organ Functions.
Zhang DM, Jiao RQ, Kong LD. Zhang DM, et al. Nutrients. 2017 Mar 29;9(4):335. doi: 10.3390/nu9040335. Nutrients. 2017. PMID: 28353649 Free PMC article. Review.
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome, disturbing tissue and organ functions. ...It is important to find the potential correlations between direct and/or indirect risk factors and healthy problems under exce …
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome, disturbing tissue and organ …
Fructose-Induced Insulin Resistance as a Model of Neuropathic Pain in Rats.
García G, Gutiérrez-Lara EJ, Centurión D, Granados-Soto V, Murbartián J. García G, et al. Neuroscience. 2019 Apr 15;404:233-245. doi: 10.1016/j.neuroscience.2019.01.063. Epub 2019 Feb 8. Neuroscience. 2019. PMID: 30742965
In this study, we investigated fructose-induced insulin resistance as a model of neuropathic pain. Insulin resistance was induced by 15% fructose in drinking water for 16 weeks. ...
In this study, we investigated fructose-induced insulin resistance as a model of neuropathic pain. Insulin re
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