Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1993 1
1995 1
2004 1
2009 1
2014 1
2020 1
2021 1
2025 1
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

8 results

Results by year

Filters applied: . Clear all
Page 1
First-pass metabolism of ethanol in human beings: effect of intravenous infusion of fructose.
Parlesak A, Billinger MH, Schäfer C, Wehner HD, Bode C, Bode JC. Parlesak A, et al. Alcohol. 2004 Oct-Nov;34(2-3):121-5. doi: 10.1016/j.alcohol.2004.06.009. Alcohol. 2004. PMID: 15902905
In the current study, the effect of fructose infusion on first-pass metabolism of ethanol was studied in human volunteers. A significantly higher first-pass metabolism of ethanol was obtained after administration of fructose …
In the current study, the effect of fructose infusion on first-pass metabolism of ethanol was studied in human v …
Dietary fructose and glucose differentially affect lipid and glucose homeostasis.
Schaefer EJ, Gleason JA, Dansinger ML. Schaefer EJ, et al. J Nutr. 2009 Jun;139(6):1257S-1262S. doi: 10.3945/jn.108.098186. Epub 2009 Apr 29. J Nutr. 2009. PMID: 19403705 Free PMC article. Review.
Absorbed glucose and fructose differ in that glucose largely escapes first-pass removal by the liver, whereas fructose does not, resulting in different metabolic effects of these 2 monosaccharides. ...Sucrose and high-fru …
Absorbed glucose and fructose differ in that glucose largely escapes first-pass removal by the liver …
Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis.
DeBosch BJ, Chen Z, Saben JL, Finck BN, Moley KH. DeBosch BJ, et al. J Biol Chem. 2014 Apr 18;289(16):10989-10998. doi: 10.1074/jbc.M113.527002. Epub 2014 Feb 11. J Biol Chem. 2014. PMID: 24519932 Free PMC article.
GLUT8 (Slc2A8) is a facilitative glucose and fructose transporter that is highly expressed in liver, heart, and other oxidative tissues. We previously demonstrated that female mice lacking GLUT8 exhibit impaired first-pass hepatic fructose …
GLUT8 (Slc2A8) is a facilitative glucose and fructose transporter that is highly expressed in liver, heart, and other o …
Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis.
Shepherd EL, Saborano R, Northall E, Matsuda K, Ogino H, Yashiro H, Pickens J, Feaver RE, Cole BK, Hoang SA, Lawson MJ, Olson M, Figler RA, Reardon JE, Nishigaki N, Wamhoff BR, Günther UL, Hirschfield G, Erion DM, Lalor PF. Shepherd EL, et al. JHEP Rep. 2020 Nov 20;3(2):100217. doi: 10.1016/j.jhepr.2020.100217. eCollection 2021 Apr. JHEP Rep. 2020. PMID: 33490936 Free PMC article.
BACKGROUND & AIMS: Increasing evidence highlights dietary fructose as a major driver of non-alcoholic fatty liver disease (NAFLD) pathogenesis, the majority of which is cleared on first pass through the hepatic circulation by enzymatic phosphorylat …
BACKGROUND & AIMS: Increasing evidence highlights dietary fructose as a major driver of non-alcoholic fatty liver disease …
Effect of the peroxisome proliferator perfluoro-n-decanoic acid on glucose transport in the isolated perfused rat liver.
Goecke-Flora CM, Wyman JF, Jarnot BM, Reo NV. Goecke-Flora CM, et al. Chem Res Toxicol. 1995 Jan-Feb;8(1):77-81. doi: 10.1021/tx00043a010. Chem Res Toxicol. 1995. PMID: 7703370
The perfluorinated carboxylic acid, perfluoro-n-decanoic acid (PFDA), is a known peroxisome proliferator which displays toxicity in rodents. Using a paired-tracer first-pass extraction technique, the effect of PFDA on hepatic glucose transport was determined …
The perfluorinated carboxylic acid, perfluoro-n-decanoic acid (PFDA), is a known peroxisome proliferator which displays toxicity in rodents. …
The Hepatic Axis Fructose-Methylglyoxal-AMPK: Starring or Secondary Role in Chronic Metabolic Disease?
Gugliucci A. Gugliucci A. J Clin Med. 2025 May 19;14(10):3559. doi: 10.3390/jcm14103559. J Clin Med. 2025. PMID: 40429553 Free PMC article.
Based on research conducted over the past decade, fructose is one of the main culprits. Over 80% of ingested fructose is metabolized by the liver at first pass, where it stimulates de novo lipogenesis (DNL) to drive hepatic triglyceride ( …
Based on research conducted over the past decade, fructose is one of the main culprits. Over 80% of ingested fructose is me …
Energy expenditure and substrate metabolism after oral fructose in patients with cirrhosis.
Kruszynska YT, Meyer-Alber A, Wollen N, McIntyre N. Kruszynska YT, et al. J Hepatol. 1993 Sep;19(2):241-51. doi: 10.1016/s0168-8278(05)80578-1. J Hepatol. 1993. PMID: 8301057
There is little information on the metabolic response to ingested fructose in patients with cirrhosis. Glucose kinetics, plasma lipid and blood lactate levels, whole body substrate oxidation rates and energy expenditure were measured following ingestion of 75 …
There is little information on the metabolic response to ingested fructose in patients with cirrhosis. Glucose kinetics …
The inhibitory effect of phlorhizin and phloretin on hexose transport in the liver.
Ibu JO, Short AH. Ibu JO, et al. Scand J Gastroenterol Suppl. 1986;124:75-81. doi: 10.3109/00365528609093786. Scand J Gastroenterol Suppl. 1986. PMID: 3508647
The present investigation was designed to find out the effects of these two chemically related substances on hexose transport in the liver. The effect of 1mM phlorhzin or ImM phloretin on the transport of D-stereoisomers of glucose, galactose and fructose usi …
The present investigation was designed to find out the effects of these two chemically related substances on hexose transport in the live …