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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 1
1966 1
1967 4
1968 7
1969 9
1970 7
1971 11
1972 16
1973 15
1974 24
1975 29
1976 15
1977 21
1978 11
1979 5
1980 5
1981 5
1982 6
1983 9
1984 6
1985 4
1986 6
1987 8
1988 4
1989 5
1990 5
1991 6
1992 2
1993 6
1994 3
1995 4
1996 6
1997 1
1998 2
1999 5
2000 4
2001 2
2002 3
2003 4
2004 3
2005 3
2006 11
2007 11
2008 28
2009 25
2010 27
2011 27
2012 40
2013 52
2014 39
2015 45
2016 40
2017 32
2018 50
2019 58
2020 62
2021 66
2022 50
2023 50
2024 37
2025 40
2026 20

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981 results

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Page 1
Fructose and uric acid in diabetic nephropathy.
Bjornstad P, Lanaspa MA, Ishimoto T, Kosugi T, Kume S, Jalal D, Maahs DM, Snell-Bergeon JK, Johnson RJ, Nakagawa T. Bjornstad P, et al. Diabetologia. 2015 Sep;58(9):1993-2002. doi: 10.1007/s00125-015-3650-4. Epub 2015 Jun 7. Diabetologia. 2015. PMID: 26049401 Free PMC article. Review.
For this reason, uric acid derived from endogenous fructose could cause tubulointerstitial injury in diabetes. ...In this review we discuss the relationship between uric acid and fructose as a novel mechanism for the development of diabet …
For this reason, uric acid derived from endogenous fructose could cause tubulointerstitial injury in diabetes. ...In th …
Fructose and Uric Acid: Major Mediators of Cardiovascular Disease Risk Starting at Pediatric Age.
Russo E, Leoncini G, Esposito P, Garibotto G, Pontremoli R, Viazzi F. Russo E, et al. Int J Mol Sci. 2020 Jun 24;21(12):4479. doi: 10.3390/ijms21124479. Int J Mol Sci. 2020. PMID: 32599713 Free PMC article. Review.
Recently, there has been a growing interest in epidemiological and clinical studies supporting a pathogenetic role of fructose in cardio-metabolic diseases, especially in children and adolescents. In the present review, we summarize experimental data on the potential biolo …
Recently, there has been a growing interest in epidemiological and clinical studies supporting a pathogenetic role of fructose in car …
Association of uric acid and fructose levels in polycystic ovary syndrome.
Feng D, Wang X, Song J, Yang H, Peng Y, Wang X, Chen W, Li P, Fang Y, Shi B, Li D. Feng D, et al. Hum Reprod. 2024 Nov 1;39(11):2575-2586. doi: 10.1093/humrep/deae219. Hum Reprod. 2024. PMID: 39380170 Free article.
STUDY QUESTION: Is there a relationship between serum uric acid and fructose levels in polycystic ovary syndrome (PCOS)? SUMMARY ANSWER: Elevated serum uric acid levels in women with PCOS positively correlate with serum fructose levels, a …
STUDY QUESTION: Is there a relationship between serum uric acid and fructose levels in polycystic ovary syndrome (PCOS) …
Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review.
Caliceti C, Calabria D, Roda A, Cicero AFG. Caliceti C, et al. Nutrients. 2017 Apr 18;9(4):395. doi: 10.3390/nu9040395. Nutrients. 2017. PMID: 28420204 Free PMC article. Review.
There is a direct relationship between fructose intake and serum levels of uric acid (UA), which is the final product of purine metabolism. ...Other dietary and pathophysiological factors are also related to UA production. However, the role of fructose …
There is a direct relationship between fructose intake and serum levels of uric acid (UA), which is the final product o …
Fructose and uric acid: is there a role in endothelial function?
Jia G, Aroor AR, Whaley-Connell AT, Sowers JR. Jia G, et al. Curr Hypertens Rep. 2014 Jun;16(6):434. doi: 10.1007/s11906-014-0434-z. Curr Hypertens Rep. 2014. PMID: 24760443 Free PMC article. Review.
Population level data support that consumption of fructose and fructose-based sweeteners has dramatically increased and suggest that high dietary intake of fructose is an important factor in the development of the cardiorenal metabolic syndrome (CRS). The CRS …
Population level data support that consumption of fructose and fructose-based sweeteners has dramatically increased and sugges …
Uric acid and fructose: potential biological mechanisms.
Lanaspa MA, Tapia E, Soto V, Sautin Y, Sánchez-Lozada LG. Lanaspa MA, et al. Semin Nephrol. 2011 Sep;31(5):426-32. doi: 10.1016/j.semnephrol.2011.08.006. Semin Nephrol. 2011. PMID: 22000649 Review.
Both conditions are well-known risk factors for cardiovascular and renal diseases. Uric acid synthesis is linked biochemically to fructose metabolism, thus the widespread consumption of this monosaccharide has been related to steady increasing levels of serum …
Both conditions are well-known risk factors for cardiovascular and renal diseases. Uric acid synthesis is linked biochemically …
Dietary fructose: from uric acid to a metabolic switch in pediatric metabolic dysfunction-associated steatotic liver disease.
Faienza MF, Cognetti E, Farella I, Antonioli A, Tini S, Antoniotti V, Prodam F. Faienza MF, et al. Crit Rev Food Sci Nutr. 2025;65(23):4583-4598. doi: 10.1080/10408398.2024.2392150. Epub 2024 Aug 19. Crit Rev Food Sci Nutr. 2025. PMID: 39157959 Free article. Review.
Fructose metabolism is involved in the liver through the classical lipogenic pathway via de novo lipogenesis (DNL) or in the alternative pathway via uric acid accumulation. Hyperuricemia is one of the main features of MALSD patients, underlining how uric …
Fructose metabolism is involved in the liver through the classical lipogenic pathway via de novo lipogenesis (DNL) or in the alternat …
Molecular aspects of fructose metabolism and metabolic disease.
Herman MA, Birnbaum MJ. Herman MA, et al. Cell Metab. 2021 Dec 7;33(12):2329-2354. doi: 10.1016/j.cmet.2021.09.010. Epub 2021 Oct 6. Cell Metab. 2021. PMID: 34619074 Free PMC article. Review.
Sugar is added to the diet in the form of sucrose or high-fructose corn syrup, both of which comprise nearly equal amounts of glucose and fructose. The unique aspects of fructose metabolism and properties of fructose-derived metabolites allow for fr …
Sugar is added to the diet in the form of sucrose or high-fructose corn syrup, both of which comprise nearly equal amounts of glucose …
Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.
Jensen T, Abdelmalek MF, Sullivan S, Nadeau KJ, Green M, Roncal C, Nakagawa T, Kuwabara M, Sato Y, Kang DH, Tolan DR, Sanchez-Lozada LG, Rosen HR, Lanaspa MA, Diehl AM, Johnson RJ. Jensen T, et al. J Hepatol. 2018 May;68(5):1063-1075. doi: 10.1016/j.jhep.2018.01.019. Epub 2018 Feb 2. J Hepatol. 2018. PMID: 29408694 Free PMC article. Review.
Recent evidence suggests that the predisposition to fatty liver is linked to the metabolism of fructose by fructokinase C, which results in ATP consumption, nucleotide turnover and uric acid generation that mediate fat accumulation. ...We suggest larger, more …
Recent evidence suggests that the predisposition to fatty liver is linked to the metabolism of fructose by fructokinase C, which resu …
Sirtuin deficiency and the adverse effects of fructose and uric acid synthesis.
Rodriguez-Iturbe B, Johnson RJ, Lanaspa MA, Nakagawa T, Garcia-Arroyo FE, Sánchez-Lozada LG. Rodriguez-Iturbe B, et al. Am J Physiol Regul Integr Comp Physiol. 2022 May 1;322(5):R347-R359. doi: 10.1152/ajpregu.00238.2021. Epub 2022 Mar 10. Am J Physiol Regul Integr Comp Physiol. 2022. PMID: 35271385 Free PMC article. Review.
Deficiency of sirtuin deacetylations is a consequence of reduced bioavailability of its cofactor nicotinamide adenine dinucleotide (NAD(+)). Uric acid-induced inflammation and oxidative stress consume NAD(+) and activation of the polyol pathway of fructose an …
Deficiency of sirtuin deacetylations is a consequence of reduced bioavailability of its cofactor nicotinamide adenine dinucleotide (NAD(+)). …
981 results