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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1959 1
1968 1
1970 1
1973 1
1974 1
1977 1
1979 2
1980 1
1981 2
1982 2
1983 4
1984 12
1985 8
1986 3
1987 15
1988 22
1989 18
1990 22
1991 34
1992 21
1993 25
1994 31
1995 29
1996 32
1997 36
1998 40
1999 42
2000 41
2001 40
2002 40
2003 48
2004 41
2005 44
2006 43
2007 47
2008 75
2009 59
2010 72
2011 84
2012 106
2013 97
2014 122
2015 132
2016 139
2017 136
2018 169
2019 197
2020 141
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2,023 results
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Page 1
Therapies from Fucoidan: An Update.
Fitton JH, Stringer DN, Karpiniec SS. Fitton JH, et al. Mar Drugs. 2015 Sep 16;13(9):5920-46. doi: 10.3390/md13095920. Mar Drugs. 2015. PMID: 26389927 Free PMC article. Review.
Fucoidans are a class of sulfated fucose-rich polysaccharides found in brown marine algae and echinoderms. Fucoidans have an attractive array of bioactivities and potential applications including immune modulation, cancer inhibition, and pathogen inhibition. ...The …
Fucoidans are a class of sulfated fucose-rich polysaccharides found in brown marine algae and echinoderms. Fucoidans have an a …
Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms.
van Weelden G, Bobiński M, Okła K, van Weelden WJ, Romano A, Pijnenborg JMA. van Weelden G, et al. Mar Drugs. 2019 Jan 7;17(1):32. doi: 10.3390/md17010032. Mar Drugs. 2019. PMID: 30621045 Free PMC article. Review.
Therefore, this review will address fucoidans structure, the bioavailability, and all known different pathways affected by fucoidan, in order to formulate fucoidans structure and activity in relation to its anti-cancer mechanisms. ...The main pathways influen …
Therefore, this review will address fucoidans structure, the bioavailability, and all known different pathways affected by fucoida …
Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo.
Park J, Cha JD, Choi KM, Lee KY, Han KM, Jang YS. Park J, et al. Int Immunopharmacol. 2017 Feb;43:91-98. doi: 10.1016/j.intimp.2016.12.006. Epub 2016 Dec 14. Int Immunopharmacol. 2017. PMID: 27987467
Studies have been focused on natural products with antibacterial and anti-inflammatory activities, such as fucoidan. Many in vivo studies have evaluated the effect of fucoidan on tumor growth, diabetes, obesity, ischemia reperfusion, and oxidative stress. However, t …
Studies have been focused on natural products with antibacterial and anti-inflammatory activities, such as fucoidan. Many in vivo stu …
Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae.
Shang Q, Shan X, Cai C, Hao J, Li G, Yu G. Shang Q, et al. Food Funct. 2016 Jul 13;7(7):3224-32. doi: 10.1039/c6fo00309e. Food Funct. 2016. PMID: 27334000
Recently, fucoidan has been proposed as a potential prebiotic agent for functional food and pharmaceutical development. However, while previous studies illustrated favorable modulations of gut microbiota by fucoidan, changes in the overall microbial structure remain …
Recently, fucoidan has been proposed as a potential prebiotic agent for functional food and pharmaceutical development. However, whil …
Fucoidan as a Potential Therapeutic for Major Blinding Diseases--A Hypothesis.
Klettner A. Klettner A. Mar Drugs. 2016 Feb 3;14(2):31. doi: 10.3390/md14020031. Mar Drugs. 2016. PMID: 26848666 Free PMC article. Review.
Some of the characteristics found in certain fucoidans, such as its anti-oxidant activity, complement inhibition or interaction with the Vascular Endothelial Growth factor, which would be of high interest for a potential application of fucoidan in age-related macula …
Some of the characteristics found in certain fucoidans, such as its anti-oxidant activity, complement inhibition or interaction with …
A review about the development of fucoidan in antitumor activity: Progress and challenges.
Wu L, Sun J, Su X, Yu Q, Yu Q, Zhang P. Wu L, et al. Carbohydr Polym. 2016 Dec 10;154:96-111. doi: 10.1016/j.carbpol.2016.08.005. Epub 2016 Aug 3. Carbohydr Polym. 2016. PMID: 27577901 Review.
Many reports have demonstrated that fucoidan has antitumor activities on various cancers. However, until now, few reviews have discussed the antitumor activity of fucoidan and few reports have summarized detailed molecular mechanisms of its actions and antitumor cha …
Many reports have demonstrated that fucoidan has antitumor activities on various cancers. However, until now, few reviews have discus …
Therapies from Fucoidan: New Developments.
Fitton HJ, Stringer DS, Park AY, Karpiniec SN. Fitton HJ, et al. Mar Drugs. 2019 Oct 9;17(10):571. doi: 10.3390/md17100571. Mar Drugs. 2019. PMID: 31601041 Free PMC article. Review.
Since our last review in 2015, the study and use of fucoidan has extended in several research areas. Clinical use of fucoidan for the treatment of renal disease has become available and human safety studies have been undertaken on radiolabeled fucoidan for th …
Since our last review in 2015, the study and use of fucoidan has extended in several research areas. Clinical use of fucoidan …
Crude Fucoidan Extracts Impair Angiogenesis in Models Relevant for Bone Regeneration and Osteosarcoma via Reduction of VEGF and SDF-1.
Wang F, Schmidt H, Pavleska D, Wermann T, Seekamp A, Fuchs S. Wang F, et al. Mar Drugs. 2017 Jun 20;15(6):186. doi: 10.3390/md15060186. Mar Drugs. 2017. PMID: 28632184 Free PMC article.
The marine origin polysaccharide fucoidan combines multiple biological activities. As demonstrated by various studies in vitro and in vivo, fucoidans show anti-viral, anti-tumor, anti-oxidant, anti-inflammatory and anti-coagulant properties, although the detailed mo …
The marine origin polysaccharide fucoidan combines multiple biological activities. As demonstrated by various studies in vitro and in …
Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms.
Citkowska A, Szekalska M, Winnicka K. Citkowska A, et al. Mar Drugs. 2019 Aug 5;17(8):458. doi: 10.3390/md17080458. Mar Drugs. 2019. PMID: 31387230 Free PMC article. Review.
Interest in fucoidan is related to its broad biological activity, including possible antioxidant, anti-inflammatory, antifungal, antiviral or antithrombotic effects. ...Advantages and limitations of fucoidan utilization in the pharmaceutical technology were also dis …
Interest in fucoidan is related to its broad biological activity, including possible antioxidant, anti-inflammatory, antifungal, anti …
Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines.
Dithmer M, Kirsch AM, Richert E, Fuchs S, Wang F, Schmidt H, Coupland SE, Roider J, Klettner A. Dithmer M, et al. Mar Drugs. 2017 Jun 22;15(7):193. doi: 10.3390/md15070193. Mar Drugs. 2017. PMID: 28640204 Free PMC article.
BACKGROUND: The polysaccharide fucoidan is widely investigated as an anti-cancer agent. Here, we tested the effect of fucoidan on uveal melanoma cell lines. ...The effect of fucoidan on VEGF was cell type and concentration dependent. In endothelial co-culture …
BACKGROUND: The polysaccharide fucoidan is widely investigated as an anti-cancer agent. Here, we tested the effect of fucoidan …
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