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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1989 2
1990 1
1991 1
1993 1
1994 2
1995 3
1996 4
1997 3
1999 3
2000 3
2001 1
2002 2
2003 3
2004 1
2005 3
2006 1
2007 2
2008 3
2010 1
2011 2
2012 3
2013 5
2014 5
2015 1
2016 4
2017 2
2018 7
2019 7
2020 13
2021 11
2022 0
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96 results
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Page 1
Fucoidan and Lung Function: Value in Viral Infection.
Fitton JH, Park AY, Karpiniec SS, Stringer DN. Fitton JH, et al. Mar Drugs. 2020 Dec 24;19(1):4. doi: 10.3390/md19010004. Mar Drugs. 2020. PMID: 33374149 Free PMC article. Review.
Compromised lung function is a feature of both infection driven and non-infective pathologies. ...Direct inhibition of SARS-CoV-2 in vitro has been described, but is not universal. This short review summarizes the current research on fucoidan with regard to viral …
Compromised lung function is a feature of both infection driven and non-infective pathologies. ...Direct inhibition of SARS-CoV-2 in …
Antitumor effect and molecular mechanism of fucoidan in NSCLC.
Chen X, Sun L, Wei X, Lu H, Tan Y, Sun Z, Jiang J. Chen X, et al. BMC Complement Med Ther. 2021 Jan 11;21(1):25. doi: 10.1186/s12906-020-03191-0. BMC Complement Med Ther. 2021. PMID: 33430854 Free PMC article.
It was recently reported that fucoidan also exerts an antitumor function. Lung cancer is one of the most common cancers in the world. ...METHODS: In vitro: Different concentrations of fucoidan were given to act on non-small cell lung cancer (NSCLC) cel …
It was recently reported that fucoidan also exerts an antitumor function. Lung cancer is one of the most common cancers in the …
Fucoidan inhibits LPS-induced acute lung injury in mice through regulating GSK-3beta-Nrf2 signaling pathway.
Zhu DZ, Wang YT, Zhuo YL, Zhu KJ, Wang XZ, Liu AJ. Zhu DZ, et al. Arch Pharm Res. 2020 Jun;43(6):646-654. doi: 10.1007/s12272-020-01234-1. Epub 2020 Jun 13. Arch Pharm Res. 2020. PMID: 32533502
The purpose of this study was to investigate the protective effects of fucoidan on Lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice. ...The results showed that LPS-induced TNF-alpha, IL-1beta, and IL-6 production, lung wet/dry (W/D) ratio, ROS …
The purpose of this study was to investigate the protective effects of fucoidan on Lipopolysaccharide (LPS)-induced acute lung
Evidence for the Fucoidan/P-Selectin Axis as a Therapeutic Target in Hypoxia-induced Pulmonary Hypertension.
Novoyatleva T, Kojonazarov B, Owczarek A, Veeroju S, Rai N, Henneke I, Böhm M, Grimminger F, Ghofrani HA, Seeger W, Weissmann N, Schermuly RT. Novoyatleva T, et al. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1407-1420. doi: 10.1164/rccm.201806-1170OC. Am J Respir Crit Care Med. 2019. PMID: 30557519
Objectives: We aimed to evaluate the therapeutic potential of targeting the fucoidan/P-selectin axis in PH. Methods: Mice with PH induced by chronic hypoxia (35 d) were given either fucoidan (from Fucus vesiculosus) or anti-P-selectin antibody (Rb40.34) during Days …
Objectives: We aimed to evaluate the therapeutic potential of targeting the fucoidan/P-selectin axis in PH. Methods: Mice with PH ind …
Fucoidan downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
Kim IH, Nam TJ. Kim IH, et al. Oncol Rep. 2018 Mar;39(3):1516-1522. doi: 10.3892/or.2018.6193. Epub 2018 Jan 4. Oncol Rep. 2018. PMID: 29328495
Fucoidan, a sulfated polysaccharide present in brown seaweed, has demonstrated anticancer activity in lung, breast, liver and colon cells. ...Fucoidan treatment (0-1,000 g/ml) was administered for 24 h in HT-29 cells. ...
Fucoidan, a sulfated polysaccharide present in brown seaweed, has demonstrated anticancer activity in lung, breast, liver and
Spray-dried fucoidan microparticles for pulmonary delivery of antitubercular drugs.
Cunha L, Rosa da Costa AM, Lourenço JP, Buttini F, Grenha A. Cunha L, et al. J Microencapsul. 2018 Jun;35(4):392-405. doi: 10.1080/02652048.2018.1513089. J Microencapsul. 2018. PMID: 30112917
Pulmonary tuberculosis accounts for 80% of cases and the delivery of antitubercular drugs into the lungs allows targeting the infected organ and, possibly, reducing systemic drug toxicity. ...Fucoidan is composed of fucose and sulphated sugar residues, moieties desc …
Pulmonary tuberculosis accounts for 80% of cases and the delivery of antitubercular drugs into the lungs allows targeting the infecte …
Fucoidan-Based Nanoparticles with Inherently Therapeutic Efficacy for Cancer Treatment.
Chiang CS, Huang BJ, Chen JY, Chieng WW, Lim SH, Lee W, Shyu WC, Jeng LB. Chiang CS, et al. Pharmaceutics. 2021 Nov 23;13(12):1986. doi: 10.3390/pharmaceutics13121986. Pharmaceutics. 2021. PMID: 34959268 Free PMC article.
The anticancer properties of fucoidan have been widely studied in cancer research. However, the lack of safety information on the parenteral administration of fucoidan and its rapid clearance from the system have limited its application. Herein, we assessed the ther …
The anticancer properties of fucoidan have been widely studied in cancer research. However, the lack of safety information on the par …
Fucoidan attenuates hyperoxia-induced lung injury in newborn rats by mediating lung fibroblasts differentiate into myofibroblasts.
Zhang Y, Du H, Yu X, Zhu J. Zhang Y, et al. Ann Transl Med. 2020 Nov;8(22):1501. doi: 10.21037/atm-20-6601. Ann Transl Med. 2020. PMID: 33313246 Free PMC article.
This study aimed to explore whether fucoidan could alleviate hyperoxia-induced lung injury in newborn rats. ...Also, fucoidan treatment significantly inhibited cell apoptosis with the elevated expression of Bcl-2/Bax in cultured lung fibroblasts. ...
This study aimed to explore whether fucoidan could alleviate hyperoxia-induced lung injury in newborn rats. ...Also, fucoid
Fucoidan induces Toll-like receptor 4-regulated reactive oxygen species and promotes endoplasmic reticulum stress-mediated apoptosis in lung cancer.
Hsu HY, Lin TY, Lu MK, Leng PJ, Tsao SM, Wu YC. Hsu HY, et al. Sci Rep. 2017 Mar 23;7:44990. doi: 10.1038/srep44990. Sci Rep. 2017. PMID: 28332554 Free PMC article.
Furthermore, ATF4 knockdown abolishes fucoidan-induced CHOP expression and rescues cell viability. Specifically, fucoidan increases intracellular reactive oxygen species (ROS), which increase ATF4 and CHOP in lung cancer cells. ...Together, these results indi …
Furthermore, ATF4 knockdown abolishes fucoidan-induced CHOP expression and rescues cell viability. Specifically, fucoidan incr …
Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells.
Hsu HY, Lin TY, Hu CH, Shu DTF, Lu MK. Hsu HY, et al. Cancer Lett. 2018 Sep 28;432:112-120. doi: 10.1016/j.canlet.2018.05.006. Epub 2018 May 8. Cancer Lett. 2018. PMID: 29746926
In addition, we observed an increasing number of clinical results that suggest combined cisplatin and fucoidan exerts a greater anti-tumorigenic effect in patients with lung cancer in Taiwan. Together, our current results support the potential of combined fucoida
In addition, we observed an increasing number of clinical results that suggest combined cisplatin and fucoidan exerts a greater anti- …
96 results