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Fucoidan attenuates radioiodine-induced salivary gland dysfunction in mice.
Kim YM, Kim JM, Kim JW, Choi ME, Kim SK, Choi JS. Kim YM, et al. BMC Oral Health. 2019 Aug 30;19(1):198. doi: 10.1186/s12903-019-0894-2. BMC Oral Health. 2019. PMID: 31470847 Free PMC article.
Changes in salivary (99m)Technetium (Tc)-pertechnetate parameters using single-photon emission computed tomography were followed. RESULTS: Salivary flow rates and lag times in the fucoidan group were improved compared to the RI-treated group. Histologic examinations of SGs …
Changes in salivary (99m)Technetium (Tc)-pertechnetate parameters using single-photon emission computed tomography were followed. RESULTS: S …
Fucoidan (Undaria pinnatifida)/Polydopamine Composite-Modified Surface Promotes Osteogenic Potential of Periodontal Ligament Stem Cells.
Kwack KH, Ji JY, Park B, Heo JS. Kwack KH, et al. Mar Drugs. 2022 Feb 28;20(3):181. doi: 10.3390/md20030181. Mar Drugs. 2022. PMID: 35323480 Free PMC article.
Current research explores the osteoinductive and osteoconductive properties of fucoidan-based composites for bone tissue engineering applications. The utility of fucoidan in a bone tissue regeneration environment necessitates a better understanding of how fucoida
Current research explores the osteoinductive and osteoconductive properties of fucoidan-based composites for bone tissue engineering …
Preparation of triamcinolone acetonide-loaded chitosan/fucoidan hydrogel and its potential application as an oral mucosa patch.
Zheng W, Hao Y, Wang D, Huang H, Guo F, Sun Z, Shen P, Sui K, Yuan C, Zhou Q. Zheng W, et al. Carbohydr Polym. 2021 Nov 15;272:118493. doi: 10.1016/j.carbpol.2021.118493. Epub 2021 Jul 29. Carbohydr Polym. 2021. PMID: 34420748
However, most of the current oral mucosa patches still have some limitations, particularly instant, poor mechanical strength and conformability, low adhesion to tissue, and foreign body sensation. Herein, triamcinolone acetonide (TA)-loaded chitosan/fucoidan (CF) composite …
However, most of the current oral mucosa patches still have some limitations, particularly instant, poor mechanical strength and conformabil …
Fucoidan affects oral squamous cell carcinoma cell functions in vitro by regulating FLNA-derived circular RNA.
Zhang N, Gao L, Ren W, Li S, Zhang D, Song X, Zhao C, Zhi K. Zhang N, et al. Ann N Y Acad Sci. 2020 Feb;1462(1):65-78. doi: 10.1111/nyas.14190. Epub 2019 Sep 8. Ann N Y Acad Sci. 2020. PMID: 31495936
The present study aimed to investigate the effectiveness of fucoidan in treating OSCC. In in vitro studies, we found that fucoidan inhibited OSCC growth and suppressed migration and invasion of OSCC cells. ...Indeed, fucoidan increased the expression of circF …
The present study aimed to investigate the effectiveness of fucoidan in treating OSCC. In in vitro studies, we found that fucoidan
Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo.
Park J, Cha JD, Choi KM, Lee KY, Han KM, Jang YS. Park J, et al. Int Immunopharmacol. 2017 Feb;43:91-98. doi: 10.1016/j.intimp.2016.12.006. Epub 2016 Dec 14. Int Immunopharmacol. 2017. PMID: 27987467
Studies have been focused on natural products with antibacterial and anti-inflammatory activities, such as fucoidan. Many in vivo studies have evaluated the effect of fucoidan on tumor growth, diabetes, obesity, ischemia reperfusion, and oxidative stress. However, t …
Studies have been focused on natural products with antibacterial and anti-inflammatory activities, such as fucoidan. Many in vivo stu …
Antitumor Effects of Fucoidan Via Apoptotic and Autophagic Induction on HSC-3 Oral Squamous CellCarcinoma.
Chantree P, Surarak T, Sangpairoj K, Aguilar P, Hitakomate E. Chantree P, et al. Asian Pac J Cancer Prev. 2020 Aug 1;21(8):2469-2477. doi: 10.31557/APJCP.2020.21.8.2469. Asian Pac J Cancer Prev. 2020. PMID: 32856880 Free PMC article.
OBJECTIVE: Many studies suggested that fucoidan has anticancer potential. The objective of the present study was to determine the cytotoxic effects and mechanism of cell death induced by fucoidan extracted from Fucus vesiculosus on HSC-3 oral squamous cell carcinoma …
OBJECTIVE: Many studies suggested that fucoidan has anticancer potential. The objective of the present study was to determine the cyt …
Oxidized low-density lipoprotein increases interleukin-8 production in human gingival epithelial cell line Ca9-22.
Suzuki K, Sakiyama Y, Usui M, Obama T, Kato R, Itabe H, Yamamoto M. Suzuki K, et al. J Periodontal Res. 2010 Aug;45(4):488-95. doi: 10.1111/j.1600-0765.2009.01263.x. Epub 2010 Apr 19. J Periodontal Res. 2010. PMID: 20412422
Production of PGE(2) by Ca9-22 cells was enhanced by co-incubation with OxLDL and interleukin-1 beta (IL-1 beta). Scavenger receptor inhibitors, fucoidan and dextran sulfate, inhibited the OxLDL-induced IL-8 and PGE(2) production in the presence of IL-1 beta. ...
Production of PGE(2) by Ca9-22 cells was enhanced by co-incubation with OxLDL and interleukin-1 beta (IL-1 beta). Scavenger receptor inhibit …
Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae.
Francischetti IM, Ma D, Andersen JF, Ribeiro JM. Francischetti IM, et al. PLoS One. 2014 Sep 10;9(9):e107295. doi: 10.1371/journal.pone.0107295. eCollection 2014. PLoS One. 2014. PMID: 25207644 Free PMC article.
Notably, lectin activity was inhibited by low concentrations of dextran sulfate 50-500 K, fucoidan, heparin, laminin, heparin sulfate proteoglycan, sialyl-containing glycans (e.g. 3'-sialyl Lewis X, and 6'-sialyl lactose), and gangliosides (e.g. GM3, GD1, GD1b, GTB1, GM1, …
Notably, lectin activity was inhibited by low concentrations of dextran sulfate 50-500 K, fucoidan, heparin, laminin, heparin sulfate …