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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 2
1993 2
1994 1
1996 1
1997 1
1998 3
1999 2
2000 2
2001 4
2002 2
2003 1
2004 2
2005 5
2006 3
2007 2
2008 1
2009 4
2010 4
2011 4
2012 7
2013 3
2014 2
2015 1
2016 7
2017 3
2018 4
2019 9
2020 5
2021 4
2022 0
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81 results
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Page 1
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.
Katayama Y, Battista M, Kao WM, Hidalgo A, Peired AJ, Thomas SA, Frenette PS. Katayama Y, et al. Cell. 2006 Jan 27;124(2):407-21. doi: 10.1016/j.cell.2005.10.041. Cell. 2006. PMID: 16439213 Free article.
Here we demonstrate that enforced HSPC egress from BM niches depends critically on the nervous system. UDP-galactose ceramide galactosyltransferase-deficient (Cgt(-/-)) mice exhibit aberrant nerve conduction and display virtually no HSPC egress from BM following gra …
Here we demonstrate that enforced HSPC egress from BM niches depends critically on the nervous system. UDP-galactose ceramide …
Potential Beneficial Actions of Fucoidan in Brain and Liver Injury, Disease, and Intoxication-Potential Implication of Sirtuins.
Dimitrova-Shumkovska J, Krstanoski L, Veenman L. Dimitrova-Shumkovska J, et al. Mar Drugs. 2020 May 5;18(5):242. doi: 10.3390/md18050242. Mar Drugs. 2020. PMID: 32380741 Free PMC article. Review.
Increased interest in natural antioxidants has brought to light the fucoidans (sulfated polysaccharides present in brown marine algae) as highly valued nutrients as well as effective and safe therapeutics against several diseases. ...Another pathway whereby fucoidan
Increased interest in natural antioxidants has brought to light the fucoidans (sulfated polysaccharides present in brown marine algae …
Fucoidan: a promising agent for brain injury and neurodegenerative disease intervention.
Wang Y, Wang Q, Han X, Ma Y, Zhang Z, Zhao L, Guan F, Ma S. Wang Y, et al. Food Funct. 2021 May 11;12(9):3820-3830. doi: 10.1039/d0fo03153d. Food Funct. 2021. PMID: 33861265 Review.
In this review, we have discussed the pharmacokinetics of fucoidan as well as the molecular mechanisms by which fucoidan exerts its neuroprotective effect on some neurological disorders. ...Although the extraction process of fucoidan has been improved well, m …
In this review, we have discussed the pharmacokinetics of fucoidan as well as the molecular mechanisms by which fucoidan exert …
Raloxifene as Treatment for Various Types of Brain Injuries and Neurodegenerative Diseases: A Good Start.
Veenman L. Veenman L. Int J Mol Sci. 2020 Oct 14;21(20):7586. doi: 10.3390/ijms21207586. Int J Mol Sci. 2020. PMID: 33066585 Free PMC article. Review.
It appears that, apart from raloxifene, to date, four nonrelated compounds have shown comparable beneficial effects-fucoidan, pifithrin, SMM-189 (5-dihydroxy-phenyl]-phenyl-methanone), and translocator protein (TSPO) ligands. ...Regarding cell types, raloxifene protects ne …
It appears that, apart from raloxifene, to date, four nonrelated compounds have shown comparable beneficial effects-fucoidan, pifithr …
Fucoidan exerts antidepressant-like effects in mice via regulating the stability of surface AMPARs.
Li M, Sun X, Li Q, Li Y, Luo C, Huang H, Chen J, Gong C, Li Y, Zheng Y, Zhang S, Huang X, Chen H. Li M, et al. Biochem Biophys Res Commun. 2020 Jan 8;521(2):318-325. doi: 10.1016/j.bbrc.2019.10.043. Epub 2019 Oct 24. Biochem Biophys Res Commun. 2020. PMID: 31668812
However, the antidepressant effects of fucoidan on chronic stress-induced depressive-like behaviors have not been well elucidated. ...Furthermore, blocking BDNF abolished the antidepressant-like effects of fucoidan in mice. Therefore, our findings clearly indicate t …
However, the antidepressant effects of fucoidan on chronic stress-induced depressive-like behaviors have not been well elucidated. .. …
Fucoidan serves a neuroprotective effect in an Alzheimer's disease model.
Subaraja M, Anantha Krishnan D, Edwin Hillary V, William Raja TR, Mathew P, Ravikumar S, Gabriel Paulraj M, Ignacimuthu S. Subaraja M, et al. Front Biosci (Elite Ed). 2020 Jan 1;12:1-34. doi: 10.2741/E855. Front Biosci (Elite Ed). 2020. PMID: 31585867 Free article.
The present study was carried out to evaluate the protective effects of fucoidan in monocrotophos induced AD in Drosophila melanogaster. In silico studies showed that fucoidan exhibited binding energy of -9.3 kcal with proteins. ...Together, the findings show that …
The present study was carried out to evaluate the protective effects of fucoidan in monocrotophos induced AD in Drosophila melanogast …
Fucoidan inhibits Ca2+ responses induced by a wide spectrum of agonists for G-protein-coupled receptors.
Wu H, Gao S, Fu M, Sakurai T, Terakawa S. Wu H, et al. Mol Med Rep. 2018 Jan;17(1):1428-1436. doi: 10.3892/mmr.2017.8035. Epub 2017 Nov 13. Mol Med Rep. 2018. PMID: 29138822 Free PMC article.
Similarly, the expressions of purinergic receptor P2Y, G-protein coupled (P2YR)1, P2YR2 and P2YR11 were significantly downregulated within cells pretreated with 1.0 mg/ml fucoidan for 3 h, and 0.5 mg/ml fucoidan significantly inhibited P2YR1 and P2YR11 expression. T …
Similarly, the expressions of purinergic receptor P2Y, G-protein coupled (P2YR)1, P2YR2 and P2YR11 were significantly downregulated within c …
Pretreated fucoidan confers neuroprotection against transient global cerebral ischemic injury in the gerbil hippocampal CA1 area via reducing of glial cell activation and oxidative stress.
Kim H, Ahn JH, Song M, Kim DW, Lee TK, Lee JC, Kim YM, Kim JD, Cho JH, Hwang IK, Yan BC, Won MH, Park JH. Kim H, et al. Biomed Pharmacother. 2019 Jan;109:1718-1727. doi: 10.1016/j.biopha.2018.11.015. Epub 2018 Nov 20. Biomed Pharmacother. 2019. PMID: 30551426 Free article.
Pretreatment with 50 mg/kg of fucoidan, not 25 mg/kg of fucoidan, attenuated tGCI-induced hyperactivity and protected CA1 pyramidal neurons from tGCI. ...Additionally, treatment with diethyldithiocarbamate (an inhibitor of SODs) to the fucoidan-treated gerbil …
Pretreatment with 50 mg/kg of fucoidan, not 25 mg/kg of fucoidan, attenuated tGCI-induced hyperactivity and protected CA1 pyra …
Fucoidan-Rich Substances from Ecklonia cava Improve Trimethyltin-Induced Cognitive Dysfunction via Down-Regulation of Amyloid beta Production/Tau Hyperphosphorylation.
Park SK, Kang JY, Kim JM, Yoo SK, Han HJ, Chung DH, Kim DO, Kim GH, Heo HJ. Park SK, et al. Mar Drugs. 2019 Oct 17;17(10):591. doi: 10.3390/md17100591. Mar Drugs. 2019. PMID: 31627432 Free PMC article.
Ecklonia cava (E. cava) was investigated to compare the effect of polyphenol and fucoidan extract and mixture (polyphenol:fucoidan = 4:6) on cognitive function. ...After a behavioral test, the inhibitory effect of lipid peroxidation and cholinergic system act …
Ecklonia cava (E. cava) was investigated to compare the effect of polyphenol and fucoidan extract and mixture (polyphenol:fucoidan
Antinociceptive effects of fucoidan in rat models of vincristine-induced neuropathic pain.
Hu C, Zhao YT, Zhang G, Xu MF. Hu C, et al. Mol Med Rep. 2017 Feb;15(2):975-980. doi: 10.3892/mmr.2016.6071. Epub 2016 Dec 23. Mol Med Rep. 2017. PMID: 28035379
However, repeated fucoidan administration attenuated vincristine-induced mechanical and cold allodynia in a dose-dependent manner. ...These results suggested that the antinociceptive effects of fucoidan may be through activation of GABAB receptor, and fucoidan
However, repeated fucoidan administration attenuated vincristine-induced mechanical and cold allodynia in a dose-dependent manner. .. …
81 results