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Anti-Allergic Activity of Fucoidan Can Be Enhanced by Coexistence with Quercetin.
Mizuno M, Fujioka A, Bitani S, Minato KI, Sakakibara H. Mizuno M, et al. Int J Mol Sci. 2022 Oct 12;23(20):12163. doi: 10.3390/ijms232012163. Int J Mol Sci. 2022. PMID: 36293027 Free PMC article.
Therefore, the purpose of this study was to search for food ingredients in vegetables that enhance type I hypersensitivity suppression effect when consumed together with fucoidan. ...The simultaneous intake of fucoidan and vegetables containing high contents …
Therefore, the purpose of this study was to search for food ingredients in vegetables that enhance type I hypersensitivity suppressio …
Fucoidan from seaweed Fucus vesiculosus inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis.
Tian T, Chang H, He K, Ni Y, Li C, Hou M, Chen L, Xu Z, Chen B, Ji M. Tian T, et al. Int Immunopharmacol. 2019 Oct;75:105823. doi: 10.1016/j.intimp.2019.105823. Epub 2019 Aug 15. Int Immunopharmacol. 2019. PMID: 31422184
However, the effects of fucoidan on atopic dermatitis (AD) have not been elucidated. To assess this, 2,4-dinitrofluorobenzene (DNFB)-treated BALB/c mice were painted with fucoidan. ...In addition, fucoidan significantly suppressed the serum levels of IgE and …
However, the effects of fucoidan on atopic dermatitis (AD) have not been elucidated. To assess this, 2,4-dinitrofluorobenzene (DNFB)- …
F-fucoidan from Saccharina japonica is a novel inducer of galectin-9 and exhibits anti-allergic activity.
Tanino Y, Hashimoto T, Ojima T, Mizuno M. Tanino Y, et al. J Clin Biochem Nutr. 2016 Jul;59(1):25-30. doi: 10.3164/jcbn.15-144. Epub 2016 May 21. J Clin Biochem Nutr. 2016. PMID: 27499575 Free PMC article.
Oral treatment with F-fucoidan suppressed allergic symptoms through the induction of galectin-9. This is the first report that F-fucoidan can induce the secretion of galectin-9....
Oral treatment with F-fucoidan suppressed allergic symptoms through the induction of galectin-9. This is the first report that F-f
Effects of oligo-fucoidan on the immune response, inflammatory status and pulmonary function in patients with asthma: a randomized, double-blind, placebo-controlled trial.
Yeh CW, Shih CJ, Liu TC, Chiou YL. Yeh CW, et al. Sci Rep. 2022 Oct 28;12(1):18150. doi: 10.1038/s41598-022-21527-3. Sci Rep. 2022. PMID: 36307493 Free PMC article. Clinical Trial.
Twenty asthmatic patients were randomly divided into two groups: (1) control group: receiving regular asthma treatment and supplementation with placebo; (2) fucoidan group: receiving regular asthma treatment and supplementation with oligo-fucoidan. ...During treatme …
Twenty asthmatic patients were randomly divided into two groups: (1) control group: receiving regular asthma treatment and supplementation w …
The role of algal fucoidans in potential anti-allergic therapeutics.
Vo TS. Vo TS. Int J Biol Macromol. 2020 Dec 15;165(Pt A):1093-1098. doi: 10.1016/j.ijbiomac.2020.09.252. Epub 2020 Oct 5. Int J Biol Macromol. 2020. PMID: 33031853 Review.
Marine environment covers a huge source of extremely potential secondary metabolites for drug discovery. Among them, fucoidans from brown seaweeds have been evidenced to possess various biological activities and health benefit effects. Notably, a great deal of interest has …
Marine environment covers a huge source of extremely potential secondary metabolites for drug discovery. Among them, fucoidans from b …
Oral Administration of Fucoidan Can Exert Anti-Allergic Activity after Allergen Sensitization by Enhancement of Galectin-9 Secretion in Blood.
Mizuno M, Sakaguchi K, Sakane I. Mizuno M, et al. Biomolecules. 2020 Feb 9;10(2):258. doi: 10.3390/biom10020258. Biomolecules. 2020. PMID: 32050429 Free PMC article.
A previous study revealed that fucoidan inhibited mast cell degranulation through the upregulation of galectin-9 in blood. ...Fucoidan increased galectin-9 mRNA expression only in colonic epithelial cells. ...
A previous study revealed that fucoidan inhibited mast cell degranulation through the upregulation of galectin-9 in blood. ...Fuco
Immunomodulation and mechanisms of fucoidan from Cladosiphon okamuranus ameliorates atopic dermatitis symptoms.
Chen BR, Hsu KT, Hsu WH, Lee BH, Li TL, Chan YL, Wu CJ. Chen BR, et al. Int J Biol Macromol. 2021 Oct 31;189:537-543. doi: 10.1016/j.ijbiomac.2021.08.001. Epub 2021 Aug 18. Int J Biol Macromol. 2021. PMID: 34416266
Therefore, there are many patients who seek complementary and alternative treatments such as healthy food. We report that fucoidan from Cladosiphon okamuranus (COP) exhibit exceptional immuno-modulatory effects significantly improving atopic dermatitis (AD) at both in vitr …
Therefore, there are many patients who seek complementary and alternative treatments such as healthy food. We report that fucoidan fr …
Sulfated polysaccharides as bioactive agents from marine algae.
Ngo DH, Kim SK. Ngo DH, et al. Int J Biol Macromol. 2013 Nov;62:70-5. doi: 10.1016/j.ijbiomac.2013.08.036. Epub 2013 Aug 28. Int J Biol Macromol. 2013. PMID: 23994790 Review.
Marine algae are rich in sulfated polysaccharides (SPs) such as carrageenans in red algae, fucoidans in brown algae and ulvans in green algae. These SPs exhibit many health beneficial nutraceutical effects such as antioxidant, anti-allergic, anti-human immunodeficiency vir …
Marine algae are rich in sulfated polysaccharides (SPs) such as carrageenans in red algae, fucoidans in brown algae and ulvans in gre …
Fucoidan suppresses IgE production in peripheral blood mononuclear cells from patients with atopic dermatitis.
Iwamoto K, Hiragun T, Takahagi S, Yanase Y, Morioke S, Mihara S, Kameyoshi Y, Hide M. Iwamoto K, et al. Arch Dermatol Res. 2011 Aug;303(6):425-31. doi: 10.1007/s00403-010-1115-7. Epub 2010 Dec 30. Arch Dermatol Res. 2011. PMID: 21191796
In this study, we examined the effect of fucoidan on IgE production in human peripheral blood mononuclear cells (PBMC) in vitro. ...The inhibitory effects of fucoidan were similarly observed for both PBMC from patients with AD and those with healthy donors. ...
In this study, we examined the effect of fucoidan on IgE production in human peripheral blood mononuclear cells (PBMC) in vitro. ...T …
The Oligo Fucoidan Inhibits Platelet-Derived Growth Factor-Stimulated Proliferation of Airway Smooth Muscle Cells.
Yang CH, Tsao CF, Ko WS, Chiou YL. Yang CH, et al. Mar Drugs. 2016 Jan 9;14(1):15. doi: 10.3390/md14010015. Mar Drugs. 2016. PMID: 26761017 Free PMC article.
Further, oligo-fucoidan supplementation reduced PDGF-stimulated extracellular signal-regulated kinase (ERK1/2), Akt, and nuclear factor (NF)-kappaB phosphorylation. Taken together, oligo-fucoidan supplementation might reduce proliferation of PDGF-treated ASMCs throu …
Further, oligo-fucoidan supplementation reduced PDGF-stimulated extracellular signal-regulated kinase (ERK1/2), Akt, and nuclear fact …
34 results