Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1997 1
1998 1
2000 1
2002 2
2003 1
2005 3
2006 1
2009 1
2010 2
2011 4
2012 3
2014 2
2015 2
2016 1
2019 3
2020 2
2021 2
2022 0
Text availability
Article attribute
Article type
Publication date

Search Results

31 results
Results by year
Filters applied: . Clear all
Page 1
Evidence for the Fucoidan/P-Selectin Axis as a Therapeutic Target in Hypoxia-induced Pulmonary Hypertension.
Novoyatleva T, Kojonazarov B, Owczarek A, Veeroju S, Rai N, Henneke I, Böhm M, Grimminger F, Ghofrani HA, Seeger W, Weissmann N, Schermuly RT. Novoyatleva T, et al. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1407-1420. doi: 10.1164/rccm.201806-1170OC. Am J Respir Crit Care Med. 2019. PMID: 30557519
Objectives: We aimed to evaluate the therapeutic potential of targeting the fucoidan/P-selectin axis in PH. Methods: Mice with PH induced by chronic hypoxia (35 d) were given either fucoidan (from Fucus vesiculosus) or anti-P-selectin antibody (Rb40.34) during Days …
Objectives: We aimed to evaluate the therapeutic potential of targeting the fucoidan/P-selectin axis in PH. Methods: Mice with PH ind …
Fucoidan from Fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy.
Zhang J, Sun Z, Lin N, Lu W, Huang X, Weng J, Sun S, Zhang C, Yang Q, Zhou G, Guo H, Chi J. Zhang J, et al. Biomed Pharmacother. 2020 Oct;130:110534. doi: 10.1016/j.biopha.2020.110534. Epub 2020 Jul 22. Biomed Pharmacother. 2020. PMID: 32711244 Free article.
In vitro, H9C2 cells were treated with the same drugs at different concentrations and intervention times. in vivo and in vitro results demonstrated that DOX administration induced myocardial damage accompanied by acceleratory apoptosis and deficient autophagy in heart tiss …
In vitro, H9C2 cells were treated with the same drugs at different concentrations and intervention times. in vivo and in vitro results demon …
A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer's Disease, Aging, Cancer, Inflammation, and Diabetes.
Akter R, Afrose A, Rahman MR, Chowdhury R, Nirzhor SSR, Khan RI, Kabir MT. Akter R, et al. Int J Mol Sci. 2021 Apr 17;22(8):4180. doi: 10.3390/ijms22084180. Int J Mol Sci. 2021. PMID: 33920726 Free PMC article. Review.
It plays a crucial role in different molecular pathways linked to DNA repair, tumorigenesis, glycolysis, gluconeogenesis, neurodegeneration, cardiac hypertrophic responses, etc. Thus, it has emerged as an exciting target of several diseases such as cancer, neurodegenerativ …
It plays a crucial role in different molecular pathways linked to DNA repair, tumorigenesis, glycolysis, gluconeogenesis, neurodegeneration, …
Early Detection of Localized Immunity in Experimental Autoimmune Myocarditis Using [(99m)Tc]Fucoidan SPECT.
Vigne J, Cognet T, Guedj K, Morvan M, Merceron O, Louedec L, Choqueux C, Nicoletti A, Escoubet B, Chaubet F, Michel JB, Rouzet F. Vigne J, et al. Mol Imaging Biol. 2020 Jun;22(3):643-652. doi: 10.1007/s11307-019-01420-8. Mol Imaging Biol. 2020. PMID: 31432389
PURPOSE: The aim of the study was to evaluate the ability of technetium-99m-fucoidan ([(99m)Tc]fucoidan), a molecular imaging agent specific for selectins, in the assessment of early localized immunity in a rat model of experimental autoimmune myocarditis (EAM). ... …
PURPOSE: The aim of the study was to evaluate the ability of technetium-99m-fucoidan ([(99m)Tc]fucoidan), a molecular imaging …
Fucoidan reduces inflammatory response in a rat model of hepatic ischemia-reperfusion injury.
Li XJ, Ye QF. Li XJ, et al. Can J Physiol Pharmacol. 2015 Nov;93(11):999-1005. doi: 10.1139/cjpp-2015-0120. Epub 2015 Jun 1. Can J Physiol Pharmacol. 2015. PMID: 26485583
Fucoidan has also shown protective effects on I/R-injured kidney and heart. However, whether fucoidan can attenuate hepatic I/R injury has not been examined. To clarify the role of fucoidan in hepatic I/R injury, Sprague-Dawley rats were subjected to s
Fucoidan has also shown protective effects on I/R-injured kidney and heart. However, whether fucoidan can attenuate hep
Therapeutic potential of fucoidan in myocardial ischemia.
Manzo-Silberman S, Louedec L, Meilhac O, Letourneur D, Michel JB, Elmadbouh I. Manzo-Silberman S, et al. J Cardiovasc Pharmacol. 2011 Dec;58(6):626-32. doi: 10.1097/FJC.0b013e3182308c64. J Cardiovasc Pharmacol. 2011. PMID: 22146406
Fucoidan, a sulfated polysaccharide extracted from brown seaweed, is a candidate for the treatment of ischemic diseases. ...Consequently, fucoidan may be useful for myocardial ischemic patients....
Fucoidan, a sulfated polysaccharide extracted from brown seaweed, is a candidate for the treatment of ischemic diseases. ...Co
Fucoidan from Undaria pinnatifida prevents vascular dysfunction through PI3K/Akt/eNOS-dependent mechanisms in the l-NAME-induced hypertensive rat model.
Li X, Li J, Li Z, Sang Y, Niu Y, Zhang Q, Ding H, Yin S. Li X, et al. Food Funct. 2016 May 18;7(5):2398-408. doi: 10.1039/c6fo00288a. Epub 2016 May 6. Food Funct. 2016. PMID: 27153123
Despite major scientific advances in its prevention, treatment and care, hypertension remains a serious condition that might lead to long-term complications such as heart disease and stroke. The great majority of forms of hypertension eventually result from an incre …
Despite major scientific advances in its prevention, treatment and care, hypertension remains a serious condition that might lead to long-te …
Cardioprotective effects of fucoidan against hypoxia-induced apoptosis in H9c2 cardiomyoblast cells.
Zhang SM, Xie ZP, Xu ML, Shi LF. Zhang SM, et al. Pharm Biol. 2015;53(9):1352-7. doi: 10.3109/13880209.2014.982298. Epub 2015 Apr 15. Pharm Biol. 2015. PMID: 25874385
CONTEXT: Cardiomyocyte apoptosis plays a critical role in the progress of heart diseases. Fucoidan, a complex-sulfated polysaccharide, has been reported to possess potential cardioprotective efficacy in vivo. OBJECTIVE: The present study determines whether …
CONTEXT: Cardiomyocyte apoptosis plays a critical role in the progress of heart diseases. Fucoidan, a complex-sulfated …
Sulfated polysaccharide fucoidan ameliorates experimental autoimmune myocarditis in rats.
Tanaka K, Ito M, Kodama M, Tomita M, Kimura S, Hoyano M, Mitsuma W, Hirono S, Hanawa H, Aizawa Y. Tanaka K, et al. J Cardiovasc Pharmacol Ther. 2011 Mar;16(1):79-86. doi: 10.1177/1074248410378751. Epub 2010 Dec 30. J Cardiovasc Pharmacol Ther. 2011. PMID: 21193680
A 21-day infusion of physiological saline or fucoidan was administrated intraperitoneally to the rats with sham operation (sham-saline, n = 5; sham-fucoidan, n = 6) or those with cardiac myosin injection (EAM-saline, n = 10; EAM-fucoidan, n = 10). After 3 wee …
A 21-day infusion of physiological saline or fucoidan was administrated intraperitoneally to the rats with sham operation (sham-salin …
Algal fucoidan, unlike heparin, has thrombolytic activity in a murine arterial thrombosis model.
Min SK, Han SM, Kim HT, Kwon OC, Lee S, Kim JK. Min SK, et al. Blood Coagul Fibrinolysis. 2012 Jul;23(5):359-66. doi: 10.1097/MBC.0b013e3283518815. Blood Coagul Fibrinolysis. 2012. PMID: 22576287
Thrombolytic effects of fucoidans were investigated in the FeCl3-induced arterial thrombus mouse model and compared with heparin and tissue plasminogen activator (t-PA). ...In the mice given either a low-molecular-weight UPS fucoidan or fucoidan source from F …
Thrombolytic effects of fucoidans were investigated in the FeCl3-induced arterial thrombus mouse model and compared with heparin and …
31 results