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Page 1
Anti-Inflammatory Activity of Fucoidan Extracts In Vitro.
Ahmad T, Eapen MS, Ishaq M, Park AY, Karpiniec SS, Stringer DN, Sohal SS, Fitton JH, Guven N, Caruso V, Eri R. Ahmad T, et al. Mar Drugs. 2021 Dec 11;19(12):702. doi: 10.3390/md19120702. Mar Drugs. 2021. PMID: 34940701 Free PMC article.
Fucoidans are sulfated, complex, fucose-rich polymers found in brown seaweeds. ...Fucoidan extracts exhibited no signs of cytotoxicity in THP-1 cells after incubation of 48 h. ...
Fucoidans are sulfated, complex, fucose-rich polymers found in brown seaweeds. ...Fucoidan extracts exhibited no signs of cyto
Combining mussel with fucoidan as a supplement for joint pain and prediabetes: Study protocol for a randomized, double-blinded, placebo-controlled trial.
Tay A, Jiang Y, Signal N, O'Brien D, Chen J, Murphy R, Lu J. Tay A, et al. Front Nutr. 2022 Sep 21;9:1000510. doi: 10.3389/fnut.2022.1000510. eCollection 2022. Front Nutr. 2022. PMID: 36211508 Free PMC article.
However, green-lipped mussel and fucoidan have never been combined. METHODS AND ANALYSIS: A parallel, two-arm, double-blind, randomized, placebo-controlled trial will be conducted in New Zealand to determine whether a food product supplemented with green-lipped mussel and …
However, green-lipped mussel and fucoidan have never been combined. METHODS AND ANALYSIS: A parallel, two-arm, double-blind, randomiz …
Antinociceptive effects of fucoidan in rat models of vincristine-induced neuropathic pain.
Hu C, Zhao YT, Zhang G, Xu MF. Hu C, et al. Mol Med Rep. 2017 Feb;15(2):975-980. doi: 10.3892/mmr.2016.6071. Epub 2016 Dec 23. Mol Med Rep. 2017. PMID: 28035379
Chemotherapeutic drugs commonly induce peripheral neuropathic pain, which limit their clinic use. In the present study, the effect of fucoidan on the development of vincristine-induced neuropathic pain was evaluated and the underlying mechanism was examined. …
Chemotherapeutic drugs commonly induce peripheral neuropathic pain, which limit their clinic use. In the present study, the effect of …
Fucoidan attenuates the existing allodynia and hyperalgesia in a rat model of neuropathic pain.
Hu C, Zhang G, Zhao YT. Hu C, et al. Neurosci Lett. 2014 Jun 13;571:66-71. doi: 10.1016/j.neulet.2014.04.030. Epub 2014 May 2. Neurosci Lett. 2014. PMID: 24792391 Free article.
The current study aimed to investigate the effects of fucoidan on the maintenance of neuropathic pain induced by L5 spinal nerve ligation (SNL) and the underlying mechanism related to the spinal neuroimmune responses. ...The analgesic effect of intrathecal fucoid
The current study aimed to investigate the effects of fucoidan on the maintenance of neuropathic pain induced by L5 spinal ner …
Enhanced Cellular Uptake in an Electrostatically Interacting Fucoidan-L-Arginine Fiber Complex.
Arunagiri V, Tsai HC, Darge HF, Hanurry EY, Lee CY, Lai JY, Wu SY. Arunagiri V, et al. Polymers (Basel). 2021 May 29;13(11):1795. doi: 10.3390/polym13111795. Polymers (Basel). 2021. PMID: 34072354 Free PMC article.
Fucoidan is an abundant marine sulfated polysaccharide extracted from the cell wall of brown macroalgae (seaweed). ...In addition, fucoidan was conjugated with cyanine 3 (Cy3) dye to track its cellular uptake. ...
Fucoidan is an abundant marine sulfated polysaccharide extracted from the cell wall of brown macroalgae (seaweed). ...In addition,
Muscle pain induced by static contraction in rats is modulated by peripheral inflammatory mechanisms.
Santos DFDSD, Melo Aquino B, Jorge CO, Azambuja G, Schiavuzzo JG, Krimon S, Neves JDS, Parada CA, Oliveira-Fusaro MCG. Santos DFDSD, et al. Neuroscience. 2017 Sep 1;358:58-69. doi: 10.1016/j.neuroscience.2017.06.041. Epub 2017 Jun 30. Neuroscience. 2017. PMID: 28673715
Muscle pain is an important health issue and frequently related to static force exertion. The aim of this study is to evaluate whether peripheral inflammatory mechanisms are involved with static contraction-induced muscle pain in rats. To this end, we developed a mo …
Muscle pain is an important health issue and frequently related to static force exertion. The aim of this study is to evaluate whethe …
Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain.
McNamee KE, Burleigh A, Gompels LL, Feldmann M, Allen SJ, Williams RO, Dawbarn D, Vincent TL, Inglis JJ. McNamee KE, et al. Pain. 2010 May;149(2):386-392. doi: 10.1016/j.pain.2010.03.002. Epub 2010 Mar 29. Pain. 2010. PMID: 20350782
TrkAd5 was highly effective at suppressing pain in both phases. Induction of NGF in the post-operative phase of pain was TNF-dependent as anti-TNF reduced NGF expression in the joint and abrogated pain. However, TNF was not regulated in the late OA joints, an …
TrkAd5 was highly effective at suppressing pain in both phases. Induction of NGF in the post-operative phase of pain was TNF-d …
Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils.
Ahn JH, Shin MC, Kim DW, Kim H, Song M, Lee TK, Lee JC, Kim H, Cho JH, Kim YM, Kim JD, Choi SY, Won MH, Park JH. Ahn JH, et al. Int J Mol Sci. 2019 Jan 28;20(3):554. doi: 10.3390/ijms20030554. Int J Mol Sci. 2019. PMID: 30696078 Free PMC article.
Fucoidan, a natural sulfated polysaccharide, displays various biological activities including antioxidant properties. ...Gerbils received HFD for 12 weeks and fucoidan (50 mg/kg) daily for the last 5 days during HFD exposure, and they were subjected to 5-min tGCI. .
Fucoidan, a natural sulfated polysaccharide, displays various biological activities including antioxidant properties. ...Gerbils rece
Antifibrotic effect of brown algae-derived fucoidans on osteoarthritic fibroblast-like synoviocytes.
Piñeiro-Ramil M, Flórez-Fernández N, Ramil-Gómez O, Torres MD, Dominguez H, Blanco FJ, Meijide-Faílde R, Vaamonde-García C. Piñeiro-Ramil M, et al. Carbohydr Polym. 2022 Apr 15;282:119134. doi: 10.1016/j.carbpol.2022.119134. Epub 2022 Jan 12. Carbohydr Polym. 2022. PMID: 35123730 Free article.
Synovial fibrosis is a pathological process which contributes to joint pain and stiffness in several musculoskeletal disorders. Fucoidans, sulfated polysaccharides found in brown algae, have recently emerged as promising therapeutic agents. ...Altogether, our result …
Synovial fibrosis is a pathological process which contributes to joint pain and stiffness in several musculoskeletal disorders. Fu
Effects of fucoidan from Fucus vesiculosus in reducing symptoms of osteoarthritis: a randomized placebo-controlled trial.
Myers SP, Mulder AM, Baker DG, Robinson SR, Rolfe MI, Brooks L, Fitton JH. Myers SP, et al. Biologics. 2016 May 26;10:81-8. doi: 10.2147/BTT.S95165. eCollection 2016. Biologics. 2016. PMID: 27307702 Free PMC article.
PURPOSE: Preliminary investigation of a fucoidan with demonstrated reduction in the symptoms of osteoarthritis (OA) of the hip and knee. ...There were no changes in the blood measurements that were of any clinical significance during the course of the study. CONCLUSION: Th …
PURPOSE: Preliminary investigation of a fucoidan with demonstrated reduction in the symptoms of osteoarthritis (OA) of the hip and kn …
31 results