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Year Number of Results
1992 1
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1999 2
2000 4
2001 2
2002 3
2003 3
2004 3
2005 4
2006 5
2007 4
2008 8
2009 6
2010 6
2011 10
2012 11
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2020 7
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Page 1
Galectin-3 and the skin.
Larsen L, Chen HY, Saegusa J, Liu FT. Larsen L, et al. J Dermatol Sci. 2011 Nov;64(2):85-91. doi: 10.1016/j.jdermsci.2011.07.008. Epub 2011 Aug 11. J Dermatol Sci. 2011. PMID: 21889881 Free PMC article. Review.
Galectin-3 is detected at different stages of melanoma development. In contrast, a marked decrease in the expression of galectin-3 is observed in non-melanoma skin cancers, such as squamous cell carcinoma (SCC) and basal cell carci
Galectin-3 is detected at different stages of melanoma development. In contrast, a marked decrease in the expression of
Galectin-3 regulation of wound healing and fibrotic processes: insights for chronic skin wound therapeutics.
McLeod K, Walker JT, Hamilton DW. McLeod K, et al. J Cell Commun Signal. 2018 Mar;12(1):281-287. doi: 10.1007/s12079-018-0453-7. Epub 2018 Jan 25. J Cell Commun Signal. 2018. PMID: 29372416 Free PMC article. Review.
Considered to have certain common properties associated with matricellular proteins, galectin-3 is expressed in the dermis and epidermis in healthy skin and is upregulated in skin healing, peaking at day 1 post wounding in mice. ...However, it appears …
Considered to have certain common properties associated with matricellular proteins, galectin-3 is expressed in the dermis and …
Galectin-3 Expression in Benign and Malignant Skin Diseases With Epidermal Hyperplasia.
Jiang ZX, Tan GZ, Shi ZR, Zhang YP, Han YF, Wang L. Jiang ZX, et al. Am J Dermatopathol. 2017 Oct;39(10):738-741. doi: 10.1097/DAD.0000000000000781. Am J Dermatopathol. 2017. PMID: 27922892
Galectin-3 has been suggested relative to tumor genesis, progression, and metastasis in basal cell carcinoma and squamous cell carcinoma that are the most common skin cancers characterized by malignant epidermal proliferation. ...Galectin-3 expr
Galectin-3 has been suggested relative to tumor genesis, progression, and metastasis in basal cell carcinoma and squamous cell
Decrease of galectin-3 in keratinocytes: A potential diagnostic marker and a critical contributor to the pathogenesis of psoriasis.
Shi ZR, Tan GZ, Cao CX, Han YF, Meng Z, Man XY, Jiang ZX, Zhang YP, Dang NN, Wei KH, Bu DF, Liu FT, Wang L. Shi ZR, et al. J Autoimmun. 2018 May;89:30-40. doi: 10.1016/j.jaut.2017.11.002. Epub 2017 Nov 20. J Autoimmun. 2018. PMID: 29167025
We report here that epidermal galectin-3 expression is significantly downregulated in lesional skin, but not in non-lesional skin in psoriasis patients, nor in a group of diseases known as psoriasiform dermatitis clinically and histologically si …
We report here that epidermal galectin-3 expression is significantly downregulated in lesional skin, but not in non-les …
Association of galectin-3 expression with melanoma progression and prognosis.
Brown ER, Doig T, Anderson N, Brenn T, Doherty V, Xu Y, Bartlett JM, Smyth JF, Melton DW. Brown ER, et al. Eur J Cancer. 2012 Apr;48(6):865-74. doi: 10.1016/j.ejca.2011.09.003. Epub 2011 Nov 7. Eur J Cancer. 2012. PMID: 22071132
METHODS: We evaluated the expression of galectin-3 in 53 cases of benign naevi, 31 cases of dysplastic naevi, 59 in-situ melanomas, 314 cases of primary melanoma and 69 metastatic melanomas using tissue microarray and immunohistochemistry. ...An …
METHODS: We evaluated the expression of galectin-3 in 53 cases of benign naevi, 31 cases of dysplastic naevi, 59 in-situ me
Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration.
Gordon-Alonso M, Hirsch T, Wildmann C, van der Bruggen P. Gordon-Alonso M, et al. Nat Commun. 2017 Oct 6;8(1):793. doi: 10.1038/s41467-017-00925-6. Nat Commun. 2017. PMID: 28986561 Free PMC article.
This mechanism requires extracellular galectin-3, a lectin secreted by tumors. Galectins bind the glycans of glycoproteins and form lattices by oligomerization. We demonstrate that galectin-3 binds the glycans of the extracellular matrix and those deco …
This mechanism requires extracellular galectin-3, a lectin secreted by tumors. Galectins bind the glycans of glycoproteins and …
Immunohistochemical galectin-3 expression in non-melanoma skin cancers.
Kapucuoglu N, Basak PY, Bircan S, Sert S, Akkaya VB. Kapucuoglu N, et al. Pathol Res Pract. 2009;205(2):97-103. doi: 10.1016/j.prp.2008.09.001. Epub 2008 Oct 31. Pathol Res Pract. 2009. PMID: 18951731
Galectin-3 expression was evaluated by immunohistochemistry in 31 SCCs, 30 BCCs, and 29 non-tumoral skin samples. Galectin-3 expression was higher in normal epidermis than in non-melanoma skin cancers, except for cytoplasmic immuno
Galectin-3 expression was evaluated by immunohistochemistry in 31 SCCs, 30 BCCs, and 29 non-tumoral skin samples. Ga
Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners.
Gallardo-Vara E, Ruiz-Llorente L, Casado-Vela J, Ruiz-Rodríguez MJ, López-Andrés N, Pattnaik AK, Quintanilla M, Bernabeu C. Gallardo-Vara E, et al. Cells. 2019 Sep 13;8(9):1082. doi: 10.3390/cells8091082. Cells. 2019. PMID: 31540324 Free PMC article.
Among these, we validated the interaction of endoglin with galectin-3, a secreted member of the lectin family with capacity to bind membrane glycoproteins, and with tripartite motif-containing protein 21 (TRIM21), an E3 ubiquitin-protein ligase. Using human endothel …
Among these, we validated the interaction of endoglin with galectin-3, a secreted member of the lectin family with capacity to …
Diagnostic and prognostic role of galectin 3 expression in cutaneous melanoma.
Abdou AG, Hammam MA, Farargy SE, Farag AG, El Shafey EN, Farouk S, Elnaidany NF. Abdou AG, et al. Am J Dermatopathol. 2010 Dec;32(8):809-14. doi: 10.1097/DAD.0b013e3181e02f29. Am J Dermatopathol. 2010. PMID: 20885286
Galectin-3 is a member of the galectin gene family and is expressed at elevated levels in a variety of neoplastic cell types. ...This study was carried out on 21 cases of melanoma and 20 benign pigmented naevi. Galectin-3 was expressed in
Galectin-3 is a member of the galectin gene family and is expressed at elevated levels in a variety of neoplastic cell
Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer.
Mollenhauer J, Deichmann M, Helmke B, Müller H, Kollender G, Holmskov U, Ligtenberg T, Krebs I, Wiemann S, Bantel-Schaal U, Madsen J, Bikker F, Klauck SM, Otto HF, Moldenhauer G, Poustka A. Mollenhauer J, et al. Int J Cancer. 2003 Jun 10;105(2):149-57. doi: 10.1002/ijc.11072. Int J Cancer. 2003. PMID: 12673672 Free article.
To improve the understanding of DMBT1/galectin-3 action in cancer, we carried out studies in skin cancer of different origins. ...Immunohistochemical analyses demonstrated absence of DMBT1/galectin-3 expression from melanocytes but induction of …
To improve the understanding of DMBT1/galectin-3 action in cancer, we carried out studies in skin cancer of different o …
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