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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1998 1
2000 3
2001 4
2002 3
2003 5
2004 3
2005 3
2006 4
2007 2
2008 3
2009 2
2010 6
2011 6
2012 9
2013 18
2014 25
2015 29
2016 32
2017 26
2018 26
2019 37
2020 48
2021 49
2022 40
2023 38
2024 20

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387 results

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Page 1
Chitinase-3 like-protein-1 function and its role in diseases.
Zhao T, Su Z, Li Y, Zhang X, You Q. Zhao T, et al. Signal Transduct Target Ther. 2020 Sep 14;5(1):201. doi: 10.1038/s41392-020-00303-7. Signal Transduct Target Ther. 2020. PMID: 32929074 Free PMC article. Review.
CHI3L1 has been strongly associated with diseases including asthma, arthritis, sepsis, diabetes, liver fibrosis, and coronary artery disease. Moreover, following its initial identification in the culture supernatant of the MG63 osteosarcoma cell line, CHI3L1 has been shown …
CHI3L1 has been strongly associated with diseases including asthma, arthritis, sepsis, diabetes, liver fibrosis, and coronary artery …
Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot.
Li Y, Li T, Zhou Z, Xiao Y. Li Y, et al. Rev Endocr Metab Disord. 2022 Jun;23(3):569-577. doi: 10.1007/s11154-021-09704-7. Epub 2022 Jan 27. Rev Endocr Metab Disord. 2022. PMID: 35083706 Free PMC article. Review.
We summarized the roles of Galectin-3 in diabetes and its complications, as well as the underlying mechanisms. Clinical research has determined that the circulating level of Galectin-3 is closely related to diabetes and its complications, …
We summarized the roles of Galectin-3 in diabetes and its complications, as well as the underlying mechanisms. Clinical …
Intracellular galectin-3 is a lipopolysaccharide sensor that promotes glycolysis through mTORC1 activation.
Chen X, Yu C, Liu X, Liu B, Wu X, Wu J, Yan D, Han L, Tang Z, Yuan X, Wang J, Wang Y, Liu S, Shan L, Shang Y. Chen X, et al. Nat Commun. 2022 Dec 8;13(1):7578. doi: 10.1038/s41467-022-35334-x. Nat Commun. 2022. PMID: 36481721 Free PMC article.
Here we report that intracellular galectin-3 interacts with Rag GTPases and Ragulator on lysosomes. We show that galectin-3 senses lipopolysaccharide (LPS) to facilitate the interaction of Rag GTPases and Ragulator, leading to the activation of mTORC1. …
Here we report that intracellular galectin-3 interacts with Rag GTPases and Ragulator on lysosomes. We show that galectin
Galectin-3 and S100A9: Novel Diabetogenic Factors Mediating Pancreatic Cancer-Associated Diabetes.
Liao WC, Huang BS, Yu YH, Yang HH, Chen PR, Huang CC, Huang HY, Wu MS, Chow LP. Liao WC, et al. Diabetes Care. 2019 Sep;42(9):1752-1759. doi: 10.2337/dc19-0217. Epub 2019 Jul 1. Diabetes Care. 2019. PMID: 31262951
In the training set, serum galectin-3 and S100A9 levels were exclusively increased in patients with PCDM and distinguished PCDM from type 2 diabetes (area under the curve [AUC] galectin-3: 0.73 [95% CI 0.64-0.83]; S100A9: 0.79 [95% CI 0.70-0.87] …
In the training set, serum galectin-3 and S100A9 levels were exclusively increased in patients with PCDM and distinguished PCD …
Current and future pharmacological therapies for NAFLD/NASH.
Sumida Y, Yoneda M. Sumida Y, et al. J Gastroenterol. 2018 Mar;53(3):362-376. doi: 10.1007/s00535-017-1415-1. Epub 2017 Dec 16. J Gastroenterol. 2018. PMID: 29247356 Free PMC article. Review.
GLP-1RA and SGLT2 inhibitors, which are currently approved for use in diabetes, have shown early efficacy in NASH, and also have beneficial cardiovascular or renal effects. ...Antifibrotic agents are a cysteine-cysteine motif chemokine receptor-2/5 antagonist (cenicriviroc …
GLP-1RA and SGLT2 inhibitors, which are currently approved for use in diabetes, have shown early efficacy in NASH, and also have bene …
Berberine alleviates oxidized low-density lipoprotein-induced macrophage activation by downregulating galectin-3 via the NF-kappaB and AMPK signaling pathways.
Pei C, Zhang Y, Wang P, Zhang B, Fang L, Liu B, Meng S. Pei C, et al. Phytother Res. 2019 Feb;33(2):294-308. doi: 10.1002/ptr.6217. Epub 2018 Nov 6. Phytother Res. 2019. PMID: 30402951 Free PMC article. Clinical Trial.
Galectin-3 expression was measured by real-time PCR, Western blotting, and confocal microscopy. ...BBR suppressed ox-LDL-induced upregulation of galectin-3 and macrophage activation. Overexpression of galectin-3 intervened the inhibitory
Galectin-3 expression was measured by real-time PCR, Western blotting, and confocal microscopy. ...BBR suppressed ox-LDL-induc
Association of circulating galectin-3 with gestational diabetes mellitus, progesterone, and insulin resistance.
Zhang Z, Kang X, Guo Y, Zhang J, Xie J, Shao S, Xiang Y, Chen G, Yu X. Zhang Z, et al. J Diabetes. 2021 Jan;13(1):54-62. doi: 10.1111/1753-0407.13088. Epub 2020 Sep 2. J Diabetes. 2021. PMID: 32671973
BACKGROUND/OBJECTIVE: Because galectin-3 has been proposed to regulate obesity and insulin resistance in mice, we hypothesized that circulating galectin-3 levels are associated with presence of gestational diabetes mellitus (GDM), progest …
BACKGROUND/OBJECTIVE: Because galectin-3 has been proposed to regulate obesity and insulin resistance in mice, we hypothesized …
Association between serum Galectin-3 and periodontitis in patients with type 2 diabetes mellitus.
Zhang Y, Wei M, Xia T, Yin W, Mao S. Zhang Y, et al. Hua Xi Kou Qiang Yi Xue Za Zhi. 2023 Dec 1;41(6):653-661. doi: 10.7518/hxkq.2023.2023192. Hua Xi Kou Qiang Yi Xue Za Zhi. 2023. PMID: 38597030 Free PMC article. Chinese, English.
OBJECTIVES: This study aims to investigate the correlation between serum Galectin-3 levels and the risk of periodontitis in patients with type 2 diabetes mellitus (T2DM). ...OBJECTIVE: This study aims to investigate the correlation between serum Gal
OBJECTIVES: This study aims to investigate the correlation between serum Galectin-3 levels and the risk of periodontitis in pa …
Galectin-3 and risk of cardiovascular events and all-cause mortality in type 2 diabetes.
Tan KCB, Cheung CL, Lee ACH, Lam JKY, Wong Y, Shiu SWM. Tan KCB, et al. Diabetes Metab Res Rev. 2019 Feb;35(2):e3093. doi: 10.1002/dmrr.3093. Epub 2018 Nov 15. Diabetes Metab Res Rev. 2019. PMID: 30378236
Experimental data suggest that galectin-3 may play a role in atherogenesis. We have evaluated whether serum galectin-3 level is associated with cardiovascular outcome in type 2 diabetes. MATERIALS AND METHODS: Galectin-3 was measur …
Experimental data suggest that galectin-3 may play a role in atherogenesis. We have evaluated whether serum galectin- …
Galectin-3 in T cell-mediated immunopathology and autoimmunity.
Srejovic IM, Lukic ML. Srejovic IM, et al. Immunol Lett. 2021 May;233:57-67. doi: 10.1016/j.imlet.2021.03.009. Epub 2021 Mar 19. Immunol Lett. 2021. PMID: 33753135
Galectin-3 (Gal-3) is the only member of galectin family able to form pentamers and heterodimers with chemokines. ...Recent data also indicate Gal-3 involvement in development atherosclerosis. In pathogenesis of diabetes type 1 and autoimmune components of
Galectin-3 (Gal-3) is the only member of galectin family able to form pentamers and heterodimers with chemokines. ...Recent da
387 results