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1995 1
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2000 3
2001 4
2002 3
2003 5
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2005 3
2006 4
2007 2
2008 3
2009 2
2010 6
2011 6
2012 9
2013 18
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2015 29
2016 31
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2018 26
2019 35
2020 46
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248 results
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Page 1
Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update.
Suthahar N, Meijers WC, Silljé HHW, Ho JE, Liu FT, de Boer RA. Suthahar N, et al. Theranostics. 2018 Jan 1;8(3):593-609. doi: 10.7150/thno.22196. eCollection 2018. Theranostics. 2018. PMID: 29344292 Free PMC article. Review.
In the last decade, considerable interest in galectin-3 has emerged because of its potential role as a biotarget. ...Galectin-3 overexpression and secretion is associated with several diseases and is extensively studied in the context of fibrosis, hear …
In the last decade, considerable interest in galectin-3 has emerged because of its potential role as a biotarget. ...Galect
Galectin-3 and S100A9: Novel Diabetogenic Factors Mediating Pancreatic Cancer-Associated Diabetes.
Liao WC, Huang BS, Yu YH, Yang HH, Chen PR, Huang CC, Huang HY, Wu MS, Chow LP. Liao WC, et al. Diabetes Care. 2019 Sep;42(9):1752-1759. doi: 10.2337/dc19-0217. Epub 2019 Jul 1. Diabetes Care. 2019. PMID: 31262951
In the training set, serum galectin-3 and S100A9 levels were exclusively increased in patients with PCDM and distinguished PCDM from type 2 diabetes (area under the curve [AUC] galectin-3: 0.73 [95% CI 0.64-0.83]; S100A9: 0.79 [95% CI 0.70-0.87] …
In the training set, serum galectin-3 and S100A9 levels were exclusively increased in patients with PCDM and distinguished PCD …
Galectin-3 and risk of cardiovascular events and all-cause mortality in type 2 diabetes.
Tan KCB, Cheung CL, Lee ACH, Lam JKY, Wong Y, Shiu SWM. Tan KCB, et al. Diabetes Metab Res Rev. 2019 Feb;35(2):e3093. doi: 10.1002/dmrr.3093. Epub 2018 Nov 15. Diabetes Metab Res Rev. 2019. PMID: 30378236
Experimental data suggest that galectin-3 may play a role in atherogenesis. We have evaluated whether serum galectin-3 level is associated with cardiovascular outcome in type 2 diabetes. MATERIALS AND METHODS: Galectin-3 was measur …
Experimental data suggest that galectin-3 may play a role in atherogenesis. We have evaluated whether serum galectin- …
Current and future pharmacological therapies for NAFLD/NASH.
Sumida Y, Yoneda M. Sumida Y, et al. J Gastroenterol. 2018 Mar;53(3):362-376. doi: 10.1007/s00535-017-1415-1. Epub 2017 Dec 16. J Gastroenterol. 2018. PMID: 29247356 Free PMC article. Review.
GLP-1RA and SGLT2 inhibitors, which are currently approved for use in diabetes, have shown early efficacy in NASH, and also have beneficial cardiovascular or renal effects. ...Antifibrotic agents are a cysteine-cysteine motif chemokine receptor-2/5 antagonist (cenicriviroc …
GLP-1RA and SGLT2 inhibitors, which are currently approved for use in diabetes, have shown early efficacy in NASH, and also have bene …
Soluble CD163 was linked to galectin-3, diabetic retinopathy and antidepressants in type 1 diabetes.
Melin EO, Dereke J, Thunander M, Hillman M. Melin EO, et al. Endocr Connect. 2018 Dec;7(12):1343-1353. doi: 10.1530/EC-18-0336. Endocr Connect. 2018. PMID: 30400063 Free PMC article.
OBJECTIVE: Depression has been associated with diabetic retinopathy and increased plasma levels of galectin-3, a lectin expressed in activated macrophages. ...RESULTS: The prevalence of depression was 10%, antidepressant medication 8%, diabetic retinop …
OBJECTIVE: Depression has been associated with diabetic retinopathy and increased plasma levels of galectin-3, a lectin …
Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance.
Li P, Liu S, Lu M, Bandyopadhyay G, Oh D, Imamura T, Johnson AMF, Sears D, Shen Z, Cui B, Kong L, Hou S, Liang X, Iovino S, Watkins SM, Ying W, Osborn O, Wollam J, Brenner M, Olefsky JM. Li P, et al. Cell. 2016 Nov 3;167(4):973-984.e12. doi: 10.1016/j.cell.2016.10.025. Cell. 2016. PMID: 27814523 Free PMC article.
In obesity, macrophages and other immune cells accumulate in insulin target tissues, promoting a chronic inflammatory state and insulin resistance. Galectin-3 (Gal3), a lectin mainly secreted by macrophages, is elevated in both obese subjects and mice. ...
In obesity, macrophages and other immune cells accumulate in insulin target tissues, promoting a chronic inflammatory state and insulin resi …
Assessment of serum galectin-3, methylated arginine and Hs-CRP levels in type 2 diabetes and prediabetes.
Atalar MN, Abuşoğlu S, Ünlü A, Tok O, İpekçi SH, Baldane S, Kebapcılar L. Atalar MN, et al. Life Sci. 2019 Aug 15;231:116577. doi: 10.1016/j.lfs.2019.116577. Epub 2019 Jun 15. Life Sci. 2019. PMID: 31211997
PURPOSE: Galectin-3 is associated with the process of inflammation and fibrosis. The aim of this study was both to evaluate of galectin-3, methylated arginines and hs-CRP in subjects with type 2 diabetes and prediabetes and to investigate a rela …
PURPOSE: Galectin-3 is associated with the process of inflammation and fibrosis. The aim of this study was both to evaluate of …
Roles of galectin-3 in metabolic disorders and tumor cell metabolism.
Li YS, Li XT, Yu LG, Wang L, Shi ZY, Guo XL. Li YS, et al. Int J Biol Macromol. 2020 Jan 1;142:463-473. doi: 10.1016/j.ijbiomac.2019.09.118. Epub 2019 Oct 8. Int J Biol Macromol. 2020. PMID: 31604080 Review.
The galactoside-binding protein galectin-3 is commonly overexpressed by cancer cells and promotes cancer progression and metastasis. Over the past few years, evidence has emerged that galectin-3 is also overexpressed in several metabolic malfunction co …
The galactoside-binding protein galectin-3 is commonly overexpressed by cancer cells and promotes cancer progression and metas …
Soluble ST2 and Galectin-3 and Progression of CKD.
Alam ML, Katz R, Bellovich KA, Bhat ZY, Brosius FC, de Boer IH, Gadegbeku CA, Gipson DS, Hawkins JJ, Himmelfarb J, Kestenbaum BR, Kretzler M, Robinson-Cohen C, Steigerwalt SP, Tuegel C, Bansal N. Alam ML, et al. Kidney Int Rep. 2018 Sep 21;4(1):103-111. doi: 10.1016/j.ekir.2018.09.013. eCollection 2019 Jan. Kidney Int Rep. 2018. PMID: 30596173 Free PMC article.
We examined associations of sST2 and galectin-3 with kidney function decline in participants with chronic kidney disease (CKD). ...We used competing risk Cox regression models to study the association of sST2 and galectin-3 with CKD progression, adjust …
We examined associations of sST2 and galectin-3 with kidney function decline in participants with chronic kidney disease (CKD) …
Elevated Platelet Galectin-3 and Rho-Associated Protein Kinase Activity Are Associated with Hemodialysis Arteriovenous Shunt Dysfunction among Subjects with Diabetes Mellitus.
Chen PW, Hsu LW, Chang HY, Huang TC, Yu JR, Liao HY, Lee CH, Liu PY. Chen PW, et al. Biomed Res Int. 2019 Apr 8;2019:8952414. doi: 10.1155/2019/8952414. eCollection 2019. Biomed Res Int. 2019. PMID: 31080833 Free PMC article.
RESULTS: Higher platelet MYPT ratios and galectin-3 levels were identified at occluded arteriovenous shunts (MYPT ratio: 0.5 [0.3-1.4] vs. 0.4 [0.3-0.6], p = 0.01; galectin-3: 1.2 [0.4-1.6] vs. 0.7 [0.1-1.2], p = 0.0004). ...Biomarker rat …
RESULTS: Higher platelet MYPT ratios and galectin-3 levels were identified at occluded arteriovenous shunts (MYPT ratio: 0.5 [ …
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