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Year Number of Results
1997 1
1999 1
2002 2
2004 1
2005 1
2006 1
2008 2
2010 2
2011 2
2012 4
2013 4
2014 9
2015 6
2016 3
2017 6
2018 2
2019 3
2020 11
2021 6
2022 1
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Overexpression of Galectin-1 and Galectin-3 in hepatocellular carcinoma.
Setayesh T, Colquhoun SD, Wan YY. Setayesh T, et al. Liver Res. 2020 Dec;4(4):173-179. doi: 10.1016/j.livres.2020.11.001. Epub 2020 Nov 4. Liver Res. 2020. PMID: 34567824 Free PMC article.
Among the 11 Gals identified in humans, the roles of Gal-1 and Gal-3 have been extensively investigated in various tumors. Here, we summarize the roles of overly expressed Gal-1 and Gal-3 in the pathogenesis of hepatocellular carcinoma (HCC). ...Additional re …
Among the 11 Gals identified in humans, the roles of Gal-1 and Gal-3 have been extensively investigated in various tumors. Here, we s …
Comparison between galectin-3 and YKL-40 levels for the assessment of liver fibrosis in cirrhotic patients.
Del Turco S, De Simone P, Ghinolfi D, Gaggini M, Basta G. Del Turco S, et al. Arab J Gastroenterol. 2021 Sep;22(3):187-192. doi: 10.1016/j.ajg.2021.03.002. Epub 2021 Jun 1. Arab J Gastroenterol. 2021. PMID: 34088622
This study aimed to evaluate the plasma protein profiles of Galectin-3 and YKL-40 in patients with cirrhosis (with and without hepatocellular carcinoma [HCC]) who underwent deceased-donor liver transplantation (LT), before and after surgery. ...CONCLUS …
This study aimed to evaluate the plasma protein profiles of Galectin-3 and YKL-40 in patients with cirrhosis (with and without …
Galectin-3 not Galectin-9 as a candidate prognosis marker for hepatocellular carcinoma.
Kong F, Jin M, Cao D, Jia Z, Liu Y, Jiang J. Kong F, et al. PeerJ. 2020 Sep 16;8:e9949. doi: 10.7717/peerj.9949. eCollection 2020. PeerJ. 2020. PMID: 32995093 Free PMC article.
The objective of this study was to estimate the expression of Gal-3 and Gal-9 in order to evaluate their relation to hepatocellular carcinoma (HCC) -related clinical features and their prognostic values. ...CONCLUSION: Gal-3 was expected to serve as a novel p …
The objective of this study was to estimate the expression of Gal-3 and Gal-9 in order to evaluate their relation to hepatocellula
Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis.
Pejnovic N, Jeftic I, Jovicic N, Arsenijevic N, Lukic ML. Pejnovic N, et al. World J Gastroenterol. 2016 Nov 28;22(44):9706-9717. doi: 10.3748/wjg.v22.i44.9706. World J Gastroenterol. 2016. PMID: 27956794 Free PMC article. Review.
Experimental models of dietary-induced NAFLD/NASH in mice on different genetic backgrounds or knockout mice with different immune reactivity are used for elucidating the pathogenesis of NASH and liver fibrosis. Galectin-3 (Gal-3), a unique chimera-type …
Experimental models of dietary-induced NAFLD/NASH in mice on different genetic backgrounds or knockout mice with different immune reactivity …
Galectin-3 is not useful for hepatocellular carcinoma surveillance in cirrhotic patients but it may be a marker of cirrhosis development.
Nassar ES, Elkalbashawy YA, Kamal A, Zakaria NHE. Nassar ES, et al. Clin Exp Hepatol. 2021 Mar;7(1):74-78. doi: 10.5114/ceh.2021.104385. Epub 2021 Mar 15. Clin Exp Hepatol. 2021. PMID: 34027118 Free PMC article.

Serum galectin-3 levels were determined in all subjects using ELISA. RESULTS: Serum galectin-3 level was significantly higher in HCC patients than in those with chronic hepatitis C (p < 0.001). ...But on comparing HCC patients with cirrhotic patient

Serum galectin-3 levels were determined in all subjects using ELISA. RESULTS: Serum galectin-3 level was signifi …
Galectin-3 and matrix metalloproteinase-9: Perspective in management of hepatocellular carcinoma.
Eisa NH, Ebrahim MA, Ragab M, Eissa LA, El-Gayar AM. Eisa NH, et al. J Oncol Pharm Pract. 2015 Oct;21(5):323-30. doi: 10.1177/1078155214532698. Epub 2014 Apr 24. J Oncol Pharm Pract. 2015. PMID: 24769518
In addition, galectin-3 level significantly increased in HCC patients with poor prognosis suffering from portal vein invasion (P = 0.014). ...CONCLUSION: MMP-9 and galectin-3 could be used as a guide for prognosis of HCC since they may play a role in H …
In addition, galectin-3 level significantly increased in HCC patients with poor prognosis suffering from portal vein invasion …
Galectin-3 favours tumour metastasis via the activation of β-catenin signalling in hepatocellular carcinoma.
Song M, Pan Q, Yang J, He J, Zeng J, Cheng S, Huang Y, Zhou ZQ, Zhu Q, Yang C, Han Y, Tang Y, Chen H, Weng DS, Xia JC. Song M, et al. Br J Cancer. 2020 Nov;123(10):1521-1534. doi: 10.1038/s41416-020-1022-4. Epub 2020 Aug 17. Br J Cancer. 2020. PMID: 32801345 Free PMC article.
BACKGROUND: High probability of metastasis limited the long-term survival of patients with hepatocellular carcinoma (HCC). Our previous study revealed that Galectin-3 was closely associated with poor prognosis in HCC patients. ...In animal models, Galectin
BACKGROUND: High probability of metastasis limited the long-term survival of patients with hepatocellular carcinoma (HCC). Our previo …
Pentraxin-3 is not related to disease severity in cirrhosis and hepatocellular carcinoma patients.
Feder S, Haberl EM, Spirk M, Weiss TS, Wiest R, Buechler C. Feder S, et al. Clin Exp Med. 2020 May;20(2):289-297. doi: 10.1007/s10238-020-00617-4. Epub 2020 Feb 20. Clin Exp Med. 2020. PMID: 32078718 Free PMC article.
The acute-phase protein pentraxin-3 (PTX3) is a component of the innate immune system. Inflammation and tissue injury increased PTX3 in the injured liver, and accordingly, circulating PTX3 was induced in patients with chronic liver diseases. ...PTX3 in the he …
The acute-phase protein pentraxin-3 (PTX3) is a component of the innate immune system. Inflammation and tissue injury increased PTX3 …
Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma.
Hsu DK, Dowling CA, Jeng KC, Chen JT, Yang RY, Liu FT. Hsu DK, et al. Int J Cancer. 1999 May 17;81(4):519-26. doi: 10.1002/(sici)1097-0215(19990517)81:4<519::aid-ijc3>3.0.co;2-0. Int J Cancer. 1999. PMID: 10225438 Free article.
In addition, galectin-3 was abundantly expressed in cirrhotic liver in peripheral distribution within regenerating nodules. Such galectin-3 expression in rapidly proliferating hepatocytes in cirrhotic liver may be a result of the high mit …
In addition, galectin-3 was abundantly expressed in cirrhotic liver in peripheral distribution within regenerating nodu …
Galectin-3 regulates hepatic progenitor cell expansion during liver injury.
Hsieh WC, Mackinnon AC, Lu WY, Jung J, Boulter L, Henderson NC, Simpson KJ, Schotanus B, Wojtacha D, Bird TG, Medine CN, Hay DC, Sethi T, Iredale JP, Forbes SJ. Hsieh WC, et al. Gut. 2015 Feb;64(2):312-21. doi: 10.1136/gutjnl-2013-306290. Epub 2014 May 16. Gut. 2015. PMID: 24837171
HPCs exist in a niche composed of myofibroblasts, macrophages and laminin matrix. Galectin-3 (Gal-3) is a beta-galactoside-binding lectin that binds to laminin and is expressed in injured liver in mice and humans. ...CONCLUSIONS: We conclude that Gal- …
HPCs exist in a niche composed of myofibroblasts, macrophages and laminin matrix. Galectin-3 (Gal-3) is a beta-galactos …
63 results