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Year Number of Results
1997 1
1999 1
2002 2
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2012 4
2013 4
2014 9
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2017 6
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74 results

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Page 1
Intracellular galectin-3 is a lipopolysaccharide sensor that promotes glycolysis through mTORC1 activation.
Chen X, Yu C, Liu X, Liu B, Wu X, Wu J, Yan D, Han L, Tang Z, Yuan X, Wang J, Wang Y, Liu S, Shan L, Shang Y. Chen X, et al. Nat Commun. 2022 Dec 8;13(1):7578. doi: 10.1038/s41467-022-35334-x. Nat Commun. 2022. PMID: 36481721 Free PMC article.
Here we report that intracellular galectin-3 interacts with Rag GTPases and Ragulator on lysosomes. We show that galectin-3 senses lipopolysaccharide (LPS) to facilitate the interaction of Rag GTPases and Ragulator, leading to the activation of mTORC1. …
Here we report that intracellular galectin-3 interacts with Rag GTPases and Ragulator on lysosomes. We show that galectin
Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis.
Pejnovic N, Jeftic I, Jovicic N, Arsenijevic N, Lukic ML. Pejnovic N, et al. World J Gastroenterol. 2016 Nov 28;22(44):9706-9717. doi: 10.3748/wjg.v22.i44.9706. World J Gastroenterol. 2016. PMID: 27956794 Free PMC article. Review.
Increased adiposity and insulin resistance contribute to the progression from hepatic steatosis to NASH and fibrosis through the development of proinflammatory and profibrotic processes in the liver, including increased hepatic infiltration of innate and adaptive immune ce …
Increased adiposity and insulin resistance contribute to the progression from hepatic steatosis to NASH and fibrosis through the development …
Overexpression of Galectin-1 and Galectin-3 in hepatocellular carcinoma.
Setayesh T, Colquhoun SD, Wan YY. Setayesh T, et al. Liver Res. 2020 Dec;4(4):173-179. doi: 10.1016/j.livres.2020.11.001. Epub 2020 Nov 4. Liver Res. 2020. PMID: 34567824 Free PMC article.
Here, we summarize the roles of overly expressed Gal-1 and Gal-3 in the pathogenesis of hepatocellular carcinoma (HCC). The overexpression of Gal-1 and Gal-3 correlates with tumor growth, HCC cell migration and invasion, tumor aggressiveness, metastasis, and poor prognosis …
Here, we summarize the roles of overly expressed Gal-1 and Gal-3 in the pathogenesis of hepatocellular carcinoma (HCC). The overexpre …
M2-like tumor-associated macrophage-related biomarkers to construct a novel prognostic signature, reveal the immune landscape, and screen drugs in hepatocellular carcinoma.
Qu X, Zhao X, Lin K, Wang N, Li X, Li S, Zhang L, Shi Y. Qu X, et al. Front Immunol. 2022 Sep 13;13:994019. doi: 10.3389/fimmu.2022.994019. eCollection 2022. Front Immunol. 2022. PMID: 36177006 Free PMC article.
We aimed to detect novel M2-like TAM-related biomarkers in hepatocellular carcinoma (HCC) via integrative analysis of single-cell RNA-seq (scRNA-seq) and bulk RNA-seq data to construct a novel prognostic signature, reveal the "immune landscape", and screen drugs in HCC. .. …
We aimed to detect novel M2-like TAM-related biomarkers in hepatocellular carcinoma (HCC) via integrative analysis of single-cell RNA …
Comparison between galectin-3 and YKL-40 levels for the assessment of liver fibrosis in cirrhotic patients.
Del Turco S, De Simone P, Ghinolfi D, Gaggini M, Basta G. Del Turco S, et al. Arab J Gastroenterol. 2021 Sep;22(3):187-192. doi: 10.1016/j.ajg.2021.03.002. Epub 2021 Jun 1. Arab J Gastroenterol. 2021. PMID: 34088622
This study aimed to evaluate the plasma protein profiles of Galectin-3 and YKL-40 in patients with cirrhosis (with and without hepatocellular carcinoma [HCC]) who underwent deceased-donor liver transplantation (LT), before and after surgery. ...CONCLUS …
This study aimed to evaluate the plasma protein profiles of Galectin-3 and YKL-40 in patients with cirrhosis (with and without …
Galectin-3 not Galectin-9 as a candidate prognosis marker for hepatocellular carcinoma.
Kong F, Jin M, Cao D, Jia Z, Liu Y, Jiang J. Kong F, et al. PeerJ. 2020 Sep 16;8:e9949. doi: 10.7717/peerj.9949. eCollection 2020. PeerJ. 2020. PMID: 32995093 Free PMC article.
The objective of this study was to estimate the expression of Gal-3 and Gal-9 in order to evaluate their relation to hepatocellular carcinoma (HCC) -related clinical features and their prognostic values. ...Multivariate analysis showed that multiple tumor (HR = 1.94, 95% C …
The objective of this study was to estimate the expression of Gal-3 and Gal-9 in order to evaluate their relation to hepatocellular c …
Galectin-3 inhibition as a potential therapeutic target in non-alcoholic steatohepatitis liver fibrosis.
Kram M. Kram M. World J Hepatol. 2023 Feb 27;15(2):201-207. doi: 10.4254/wjh.v15.i2.201. World J Hepatol. 2023. PMID: 36926236 Free PMC article. Review.
Nonalcoholic fatty liver disease continues to be one of the major health challenges facing the world, with estimates of non-alcoholic steatohepatitis (NASH) prevalence in over 25 percent of the world's population. ...Galectin-3 inhibition is being explored as …
Nonalcoholic fatty liver disease continues to be one of the major health challenges facing the world, with estimates of non-alcoholic …
Unraveling the pathophysiologic role of galectin-3 in chronically injured liver.
Ezhilarasan D. Ezhilarasan D. J Cell Physiol. 2023 Apr;238(4):673-686. doi: 10.1002/jcp.30956. Epub 2023 Feb 6. J Cell Physiol. 2023. PMID: 36745560 Review.
Galectin-3 (Gal-3) previously referred to as S-type lectins, is a soluble protein that specifically binds to beta-galactoside carbohydrates with high specificity. Gal-3 plays a pivotal role in a variety of pathophysiological processes such as cell proliferation, inf
Galectin-3 (Gal-3) previously referred to as S-type lectins, is a soluble protein that specifically binds to beta-galactoside
Galectin-3 and matrix metalloproteinase-9: Perspective in management of hepatocellular carcinoma.
Eisa NH, Ebrahim MA, Ragab M, Eissa LA, El-Gayar AM. Eisa NH, et al. J Oncol Pharm Pract. 2015 Oct;21(5):323-30. doi: 10.1177/1078155214532698. Epub 2014 Apr 24. J Oncol Pharm Pract. 2015. PMID: 24769518
In addition, galectin-3 level significantly increased in HCC patients with poor prognosis suffering from portal vein invasion (P = 0.014). ...CONCLUSION: MMP-9 and galectin-3 could be used as a guide for prognosis of HCC since they may play a role in H …
In addition, galectin-3 level significantly increased in HCC patients with poor prognosis suffering from portal vein invasion …
Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma.
Hsu DK, Dowling CA, Jeng KC, Chen JT, Yang RY, Liu FT. Hsu DK, et al. Int J Cancer. 1999 May 17;81(4):519-26. doi: 10.1002/(sici)1097-0215(19990517)81:4<519::aid-ijc3>3.0.co;2-0. Int J Cancer. 1999. PMID: 10225438 Free article.
In addition, galectin-3 was abundantly expressed in cirrhotic liver in peripheral distribution within regenerating nodules. Such galectin-3 expression in rapidly proliferating hepatocytes in cirrhotic liver may be a result of the high mit …
In addition, galectin-3 was abundantly expressed in cirrhotic liver in peripheral distribution within regenerating nodu …
74 results