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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 3
1993 1
1995 2
1996 3
1997 2
1998 4
1999 5
2000 6
2001 8
2002 13
2003 11
2004 22
2005 18
2006 20
2007 11
2008 15
2009 13
2010 23
2011 24
2012 24
2013 27
2014 26
2015 17
2016 14
2017 23
2018 21
2019 16
2020 19
2021 10
2022 11
2023 0
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372 results
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Page 1
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.
Vuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SEM, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pedersen A, Gravelle L, Tantawi S, Schambye H, Sethi T, MacKinnon AC. Vuong L, et al. Cancer Res. 2019 Apr 1;79(7):1480-1492. doi: 10.1158/0008-5472.CAN-18-2244. Epub 2019 Jan 23. Cancer Res. 2019. PMID: 30674531
To examine the role of galectin-3 inhibition in NSCLC, we tested the effects of galectin-3 depletion using genetic and pharmacologic approaches on syngeneic mouse lung adenocarcinoma and human lung adenocarcinoma xenografts. …
To examine the role of galectin-3 inhibition in NSCLC, we tested the effects of galectin-3 depletion using genet …
Progress in molecular-based management of differentiated thyroid cancer.
Xing M, Haugen BR, Schlumberger M. Xing M, et al. Lancet. 2013 Mar 23;381(9871):1058-69. doi: 10.1016/S0140-6736(13)60109-9. Epub 2013 Mar 22. Lancet. 2013. PMID: 23668556 Free PMC article. Review.
Diagnostic molecular markers, such as RET-PTC, RAS, and BRAF(V600E) mutations; galectin 3; and a new gene expression classifier, are outstanding examples that have improved diagnosis of thyroid nodules. ...
Diagnostic molecular markers, such as RET-PTC, RAS, and BRAF(V600E) mutations; galectin 3; and a new gene expression classifie …
Papillary thyroid carcinoma behavior: clues in the tumor microenvironment.
Bergdorf K, Ferguson DC, Mehrad M, Ely K, Stricker T, Weiss VL. Bergdorf K, et al. Endocr Relat Cancer. 2019 Jun;26(6):601-614. doi: 10.1530/ERC-19-0074. Endocr Relat Cancer. 2019. PMID: 30965283 Free PMC article.
In addition, dendritic cells positively correlate with tall cell morphology (OR = 4.5, CI = 1.6-13, P = 4.9 10-3) and neutrophils negatively correlate with follicular morphology (OR = 1.3 10-3, CI = 5.3 10-5-0.031, P = 4.1 10-5). TIDE analysis indicate …
In addition, dendritic cells positively correlate with tall cell morphology (OR = 4.5, CI = 1.6-13, P = 4.9 10-3) and neutrophils neg …
Mucins and mucin binding proteins in colorectal cancer.
Byrd JC, Bresalier RS. Byrd JC, et al. Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):77-99. doi: 10.1023/a:1025815113599. Cancer Metastasis Rev. 2004. PMID: 15000151 Review.
There are, however, cancer-associated increases in sialyl LeX and related structures on mucins and other glycoproteins that can serve as ligands for selectins, increasing the metastatic capacity of colon cancer cells. The endogenous galactoside-binding protein galectin- …
There are, however, cancer-associated increases in sialyl LeX and related structures on mucins and other glycoproteins that can serve as lig …
Galectin-3 and PTEN expression in pancreatic ductal adenocarcinoma, pancreatic neuroendocrine neoplasms and gastrointestinal tumors on fine-needle aspiration cytology.
Jiang K, Lawson D, Cohen C, Siddiqui MT. Jiang K, et al. Acta Cytol. 2014;58(3):281-7. doi: 10.1159/000362221. Epub 2014 May 13. Acta Cytol. 2014. PMID: 24854395 Free article.
OBJECTIVE: Galectin-3 has been implicated in the carcinogenesis of pancreatic ductal adenocarcinoma (PDAC). ...RESULTS: Forty-four of 46 PDAC FNA and 32 of 33 PDAC TMA demonstrated tumor-specific Galectin-3 positivity. In contrast, Galectin …
OBJECTIVE: Galectin-3 has been implicated in the carcinogenesis of pancreatic ductal adenocarcinoma (PDAC). ...RESULTS: …
Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors.
Ajani JA, Estrella JS, Chen Q, Correa AM, Ma L, Scott AW, Jin J, Liu B, Xie M, Sudo K, Shiozaki H, Badgwell B, Weston B, Lee JH, Bhutani MS, Onodera H, Suzuki K, Suzuki A, Ding S, Hofstetter WL, Johnson RL, Bresalier RS, Song S. Ajani JA, et al. Br J Cancer. 2018 Jan;118(1):52-61. doi: 10.1038/bjc.2017.388. Epub 2017 Nov 14. Br J Cancer. 2018. PMID: 29136404 Free PMC article.
BACKGROUND: Overexpression of Galectin-3 (Gal-3), a beta-galactoside binding protein, has been noted in many tumour types but its functional significance and clinical utility in gastric adenocarcinoma (GAC) are not well known. ...Gal-3 overexpre …
BACKGROUND: Overexpression of Galectin-3 (Gal-3), a beta-galactoside binding protein, has been noted in many tumour typ …
Galectin-3 immunoprofile in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands.
Ferrazzo KL, Alves SM Jr, Santos E, Martins MT, de Sousa SM. Ferrazzo KL, et al. Oral Oncol. 2007 Jul;43(6):580-5. doi: 10.1016/j.oraloncology.2006.06.010. Epub 2006 Sep 25. Oral Oncol. 2007. PMID: 16996782
In normal salivary glands there was strong nuclear and cytoplasmic staining for galectin-3 in ductal luminal cells. ACC showed specific staining in luminal cells mainly in the nuclei. In the tubular subtype of ACC, galectin-3 strongly stained luminal c …
In normal salivary glands there was strong nuclear and cytoplasmic staining for galectin-3 in ductal luminal cells. ACC showed …
Diagnostic utility of CK19 and galectin-3 in differentiating papillary thyroid carcinoma from nonneoplastic lesions of thyroid.
Prasad PA, Raju K. Prasad PA, et al. J Cancer Res Ther. 2022 Apr-Jun;18(3):644-649. doi: 10.4103/jcrt.jcrt_563_21. J Cancer Res Ther. 2022. PMID: 35900535
There was a statistically significant association (P = 0.003) of galectin-3 expression between PTC and nonneoplastic cases. CONCLUSION: Galectin-3 expression can be used to differentiate PTC from nonneoplastic lesions of thyroid in ambiguous cases. …
There was a statistically significant association (P = 0.003) of galectin-3 expression between PTC and nonneoplastic cases. CO …
Expression and Distribution of Galectin-3 in Chromophobe and Papillary Carcinomas.
Cioca A, Muntean D, Bungardean C, Raica M, Cimpean AM. Cioca A, et al. Anticancer Res. 2018 Jan;38(1):259-263. doi: 10.21873/anticanres.12216. Anticancer Res. 2018. PMID: 29277781
Moreover, the optimal therapy for patients with non-clear renal cell carcinoma (RCC) is unknown yet. Although elevated levels of Galectin-3 (Gal-3) were associated with poor prognosis in conventional RCC, the impact of this protein on carcinogenesis of chromo …
Moreover, the optimal therapy for patients with non-clear renal cell carcinoma (RCC) is unknown yet. Although elevated levels of Galectin …
Galectin-3 expression in uterine endometrioid adenocarcinoma: comparison of staining in conventional tumor glands and in areas of MELF pattern myometrial invasion.
Stewart CJ, Crook ML. Stewart CJ, et al. Int J Gynecol Pathol. 2010 Nov;29(6):555-61. doi: 10.1097/PGP.0b013e3181e4ee4ea. Int J Gynecol Pathol. 2010. PMID: 20881856
Cytoplasmic galectin-3 was present in all tumors although <50% of cells were stained in approximately one-third of the cases. ...As MELF pattern invasion is associated with the loss of galectin-3 expression, there may be implications for the use of …
Cytoplasmic galectin-3 was present in all tumors although <50% of cells were stained in approximately one-third of the case …
372 results