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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 2
1992 1
1993 3
1994 3
1995 5
1996 8
1997 1
1998 9
1999 4
2000 6
2001 8
2002 9
2003 5
2004 11
2005 11
2006 22
2007 18
2008 18
2009 22
2010 18
2011 21
2012 28
2013 26
2014 15
2015 28
2016 24
2017 23
2018 22
2019 36
2020 32
2021 26
2022 17
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422 results
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Page 1
Galectin-3 in T cell-mediated immunopathology and autoimmunity.
Srejovic IM, Lukic ML. Srejovic IM, et al. Immunol Lett. 2021 May;233:57-67. doi: 10.1016/j.imlet.2021.03.009. Epub 2021 Mar 19. Immunol Lett. 2021. PMID: 33753135
Galectin-3 (Gal-3) is the only member of galectin family able to form pentamers and heterodimers with chemokines. ...As a regulator of immune response and T-cell activity, Gal-3 appears to have important role in development of auto
Galectin-3 (Gal-3) is the only member of galectin family able to form pentamers and heterodimers with chemokines
Galectin-3 modulation of T-cell activation: mechanisms of membrane remodelling.
Gilson RC, Gunasinghe SD, Johannes L, Gaus K. Gilson RC, et al. Prog Lipid Res. 2019 Oct;76:101010. doi: 10.1016/j.plipres.2019.101010. Epub 2019 Nov 1. Prog Lipid Res. 2019. PMID: 31682868 Review.
Galectin-3 (Gal3) is a multifaceted protein which belongs to a family of lectins and binds beta-galactosides. ...In this review, we seek to give an overview of the mechanisms by which Gal3 alters the spatial organization of cell membranes and how these proces
Galectin-3 (Gal3) is a multifaceted protein which belongs to a family of lectins and binds beta-galactosides. ...In this revie
Papillary thyroid carcinoma behavior: clues in the tumor microenvironment.
Bergdorf K, Ferguson DC, Mehrad M, Ely K, Stricker T, Weiss VL. Bergdorf K, et al. Endocr Relat Cancer. 2019 Jun;26(6):601-614. doi: 10.1530/ERC-19-0074. Endocr Relat Cancer. 2019. PMID: 30965283 Free PMC article.
Computational immunogenomic analysis was performed on 568 PTC samples in The Cancer Genome Atlas using CIBERSORT, TIMER and TIDE deconvolution analytic tools for characterizing immune cell composition. Immune cell infiltrates were correlated with histologic type, mu …
Computational immunogenomic analysis was performed on 568 PTC samples in The Cancer Genome Atlas using CIBERSORT, TIMER and TIDE deconvoluti …
Selective effects of ginseng pectins on galectin-3-mediated T cell activation and apoptosis.
Xue H, Zhao Z, Lin Z, Geng J, Guan Y, Song C, Zhou Y, Tai G. Xue H, et al. Carbohydr Polym. 2019 Sep 1;219:121-129. doi: 10.1016/j.carbpol.2019.05.023. Epub 2019 May 8. Carbohydr Polym. 2019. PMID: 31151509
Galectin-3 (Gal-3) can induce T-cell activation and apoptosis and plays a role in tumor immune tolerance. Here, we demonstrate that ginseng pectins selectively inhibit Gal-3-induced T-cell apoptosis, while not affecting T
Galectin-3 (Gal-3) can induce T-cell activation and apoptosis and plays a role in tumor immune tolerance.
Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor.
Curti BD, Koguchi Y, Leidner RS, Rolig AS, Sturgill ER, Sun Z, Wu Y, Rajamanickam V, Bernard B, Hilgart-Martiszus I, Fountain CB, Morris G, Iwamoto N, Shimada T, Chang S, Traber PG, Zomer E, Horton JR, Shlevin H, Redmond WL. Curti BD, et al. J Immunother Cancer. 2021 Apr;9(4):e002371. doi: 10.1136/jitc-2021-002371. J Immunother Cancer. 2021. PMID: 33837055 Free PMC article. Clinical Trial.
BACKGROUND: PD-1/PD-L1 engagement and overexpression of galectin-3 (Gal-3) are critical mechanisms of tumor-induced immune suppression that contribute to immunotherapy resistance. ...Increased baseline expression of Gal-3+ tumor cells and PD-1+CD8+ …
BACKGROUND: PD-1/PD-L1 engagement and overexpression of galectin-3 (Gal-3) are critical mechanisms of tumor-induced imm …
Galectin-3 regulates T-cell functions.
Hsu DK, Chen HY, Liu FT. Hsu DK, et al. Immunol Rev. 2009 Jul;230(1):114-27. doi: 10.1111/j.1600-065X.2009.00798.x. Immunol Rev. 2009. PMID: 19594632 Review.
These include viral transactivating factors, T-cell receptor (TCR) ligation, and calcium ionophores. In addition, galectin-3 is constitutively expressed in human regulatory T cells and CD4+ memory T cells. ...The rapid expansion of the fi …
These include viral transactivating factors, T-cell receptor (TCR) ligation, and calcium ionophores. In addition, galectin
Intracellular Galectin-3 Is Essential for OX40-Mediated Memory CD8+ T Cell Development.
Amani MF, Rolig AS, Redmond WL. Amani MF, et al. J Immunol. 2020 Oct 1;205(7):1857-1866. doi: 10.4049/jimmunol.1901052. Epub 2020 Aug 26. J Immunol. 2020. PMID: 32848035 Free article.
Interestingly, TCR stimulation in the presence of IL-2 upregulates intracellular expression of the beta-galactoside binding protein, Galectin-3 (Gal-3). Gal-3 has been shown to regulate Th1/Th2 polarization of CD4(+) T cells; however, the extent …
Interestingly, TCR stimulation in the presence of IL-2 upregulates intracellular expression of the beta-galactoside binding protein, Gale
Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.
Rios FJ, Zou ZG, Harvey AP, Harvey KY, Nosalski R, Anyfanti P, Camargo LL, Lacchini S, Ryazanov AG, Ryazanova L, McGrath S, Guzik TJ, Goodyear CS, Montezano AC, Touyz RM. Rios FJ, et al. Cardiovasc Res. 2020 Mar 1;116(3):721-735. doi: 10.1093/cvr/cvz164. Cardiovasc Res. 2020. PMID: 31250885 Free PMC article.
These processes were associated with infiltration of inflammatory cells (F4/80+CD206+ cardiac macrophages) and increased galectin-3 expression. Cardiac [Mg2+]i, but not [Ca2+]i, was reduced in TRPM7+/deltakinase mice. ...Vascular functional and inflammatory response …
These processes were associated with infiltration of inflammatory cells (F4/80+CD206+ cardiac macrophages) and increased galectin- …
Berberine alleviates oxidized low-density lipoprotein-induced macrophage activation by downregulating galectin-3 via the NF-κB and AMPK signaling pathways.
Pei C, Zhang Y, Wang P, Zhang B, Fang L, Liu B, Meng S. Pei C, et al. Phytother Res. 2019 Feb;33(2):294-308. doi: 10.1002/ptr.6217. Epub 2018 Nov 6. Phytother Res. 2019. PMID: 30402951 Free PMC article. Clinical Trial.
Galectin-3 expression was measured by real-time PCR, Western blotting, and confocal microscopy. ...BBR suppressed ox-LDL-induced upregulation of galectin-3 and macrophage activation. Overexpression of galectin-3 intervened the inhibitory
Galectin-3 expression was measured by real-time PCR, Western blotting, and confocal microscopy. ...BBR suppressed ox-LDL-induc
Proteomics analysis of bladder cancer exosomes.
Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. Welton JL, et al. Mol Cell Proteomics. 2010 Jun;9(6):1324-38. doi: 10.1074/mcp.M000063-MCP201. Epub 2010 Mar 11. Mol Cell Proteomics. 2010. PMID: 20224111 Free PMC article.
Exosomes are nanometer-sized vesicles, secreted by various cell types, present in biological fluids that are particularly rich in membrane proteins. ...Validation of 18 MS protein identifications (including basigin, galectin-3, trophoblast glycoprotein (5T4), …
Exosomes are nanometer-sized vesicles, secreted by various cell types, present in biological fluids that are particularly rich in mem …
422 results