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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 2
1992 1
1993 3
1994 3
1995 5
1996 8
1997 1
1998 9
1999 4
2000 6
2001 8
2002 9
2003 5
2004 11
2005 11
2006 22
2007 18
2008 18
2009 22
2010 18
2011 21
2012 28
2013 26
2014 15
2015 28
2016 24
2017 23
2018 22
2019 35
2020 30
2021 26
2022 32
2023 27
2024 11

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466 results

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Page 1
Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases.
Fan Y, Song S, Li Y, Dhar SS, Jin J, Yoshimura K, Yao X, Wang R, Scott AW, Pizzi MP, Wu J, Ma L, Calin GA, Hanash S, Wang L, Curran M, Ajani JA. Fan Y, et al. Cancer Res. 2023 Nov 15;83(22):3726-3738. doi: 10.1158/0008-5472.CAN-23-0783. Cancer Res. 2023. PMID: 37738407 Free PMC article.
Here, we found that CD47 was highly expressed on malignant PC cells, and elevated CD47 was associated with poor prognosis. Galectin-3 (Gal3) expression correlated with CD47 expression, and coexpression of Gal3 and CD47 was significantly associated with diffuse type, …
Here, we found that CD47 was highly expressed on malignant PC cells, and elevated CD47 was associated with poor prognosis. Galectin- …
Galectin-3 in T cell-mediated immunopathology and autoimmunity.
Srejovic IM, Lukic ML. Srejovic IM, et al. Immunol Lett. 2021 May;233:57-67. doi: 10.1016/j.imlet.2021.03.009. Epub 2021 Mar 19. Immunol Lett. 2021. PMID: 33753135
Galectin-3 (Gal-3) is the only member of galectin family able to form pentamers and heterodimers with chemokines. ...These differences in action of Gal-3 are related to the localization of Gal-3 in the cell, types of receptors through which it acts, or the types of
Galectin-3 (Gal-3) is the only member of galectin family able to form pentamers and heterodimers with chemokines. ...These dif
Galectin-3 regulates T-cell functions.
Hsu DK, Chen HY, Liu FT. Hsu DK, et al. Immunol Rev. 2009 Jul;230(1):114-27. doi: 10.1111/j.1600-065X.2009.00798.x. Immunol Rev. 2009. PMID: 19594632 Review.
These include viral transactivating factors, T-cell receptor (TCR) ligation, and calcium ionophores. In addition, galectin-3 is constitutively expressed in human regulatory T cells and CD4+ memory T cells. ...The rapid expansion of the field of galecti …
These include viral transactivating factors, T-cell receptor (TCR) ligation, and calcium ionophores. In addition, galectin
Galectin-3 modulation of T-cell activation: mechanisms of membrane remodelling.
Gilson RC, Gunasinghe SD, Johannes L, Gaus K. Gilson RC, et al. Prog Lipid Res. 2019 Oct;76:101010. doi: 10.1016/j.plipres.2019.101010. Epub 2019 Nov 1. Prog Lipid Res. 2019. PMID: 31682868 Review.
Galectin-3 (Gal3) is a multifaceted protein which belongs to a family of lectins and binds beta-galactosides. ...Its multivalent capacity allows Gal3 to interact specifically with different membrane proteins and lipids, influencing endocytosis, trafficking and T
Galectin-3 (Gal3) is a multifaceted protein which belongs to a family of lectins and binds beta-galactosides. ...Its multivale
Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration.
Tabel M, Wolf A, Szczepan M, Xu H, Jägle H, Moehle C, Chen M, Langmann T. Tabel M, et al. J Neuroinflammation. 2022 Sep 17;19(1):229. doi: 10.1186/s12974-022-02589-6. J Neuroinflammation. 2022. PMID: 36115971 Free PMC article.
Here, we hypothesized that genetic deficiency of galectin-3 or its modulation via TD139 dampens mononuclear phagocyte reactivity and delays retinal degeneration. METHODS: Galectin-3 expression in AMD patients was analyzed by immunohistochemical stainin …
Here, we hypothesized that genetic deficiency of galectin-3 or its modulation via TD139 dampens mononuclear phagocyte reactivi …
Berberine alleviates oxidized low-density lipoprotein-induced macrophage activation by downregulating galectin-3 via the NF-kappaB and AMPK signaling pathways.
Pei C, Zhang Y, Wang P, Zhang B, Fang L, Liu B, Meng S. Pei C, et al. Phytother Res. 2019 Feb;33(2):294-308. doi: 10.1002/ptr.6217. Epub 2018 Nov 6. Phytother Res. 2019. PMID: 30402951 Free PMC article. Clinical Trial.
Galectin-3 expression was measured by real-time PCR, Western blotting, and confocal microscopy. ...BBR suppressed ox-LDL-induced upregulation of galectin-3 and macrophage activation. Overexpression of galectin-3 intervened the inhibitory
Galectin-3 expression was measured by real-time PCR, Western blotting, and confocal microscopy. ...BBR suppressed ox-LDL-induc
Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation.
Mohammadpour H, Tsuji T, MacDonald CR, Sarow JL, Rosenheck H, Daneshmandi S, Choi JE, Qiu J, Matsuzaki J, Witkiewicz AK, Attwood K, Blazar BR, Odunsi K, Repasky EA, McCarthy PL. Mohammadpour H, et al. Cell Rep. 2023 Mar 28;42(3):112250. doi: 10.1016/j.celrep.2023.112250. Epub 2023 Mar 15. Cell Rep. 2023. PMID: 36924493 Free PMC article.
Despite an increase in our knowledge of the pathobiology of acute graft versus host disease (aGvHD), the mechanisms regulating the proliferation and function of donor T cells remain unclear. Here, we show that activated donor T cells express galectin-3 (Gal-3) after …
Despite an increase in our knowledge of the pathobiology of acute graft versus host disease (aGvHD), the mechanisms regulating the prolifera …
The immunological potential of galectin-1 and -3.
Dhirapong A, Lleo A, Leung P, Gershwin ME, Liu FT. Dhirapong A, et al. Autoimmun Rev. 2009 Mar;8(5):360-3. doi: 10.1016/j.autrev.2008.11.009. Epub 2008 Dec 6. Autoimmun Rev. 2009. PMID: 19064001 Review.
Top Reads.
[No authors listed] [No authors listed] J Immunol. 2019 Nov 15;203(10):2559-2560. doi: 10.4049/jimmunol.1990020. J Immunol. 2019. PMID: 31685699 No abstract available.
Intracellular Galectin-3 Is Essential for OX40-Mediated Memory CD8(+) T Cell Development.
Amani MF, Rolig AS, Redmond WL. Amani MF, et al. J Immunol. 2020 Oct 1;205(7):1857-1866. doi: 10.4049/jimmunol.1901052. Epub 2020 Aug 26. J Immunol. 2020. PMID: 32848035
Interestingly, TCR stimulation in the presence of IL-2 upregulates intracellular expression of the beta-galactoside binding protein, Galectin-3 (Gal-3). Gal-3 has been shown to regulate Th1/Th2 polarization of CD4(+) T cells; however, the extent to which Gal-3 regul …
Interestingly, TCR stimulation in the presence of IL-2 upregulates intracellular expression of the beta-galactoside binding protein, Gale
466 results